id stringlengths 11 22 | document_id stringlengths 11 22 | passages list | entities list | events list | coreferences list | relations list |
|---|---|---|---|---|---|---|
PMID-7511490 | PMID-7511490 | [
{
"id": "PMID-7511490__text",
"type": "abstract",
"text": [
"Additional tests of interest to the dermatologist.\nThe carcinoid syndrome and its clinical manifestations have been discussed. The standard laboratory test for making that diagnosis is urinary 5-HIAA levels but newer, more sensitive tes... | [
{
"id": "PMID-7511490_T1",
"type": "Organism_substance",
"text": [
"urinary"
],
"offsets": [
[
185,
192
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-15193260 | PMID-15193260 | [
{
"id": "PMID-15193260__text",
"type": "abstract",
"text": [
"Dynein light chain 1, a p21-activated kinase 1-interacting substrate, promotes cancerous phenotypes. \nWe identified dynein light chain 1 (DLC1) as a physiologic substrate of p21-activated kinase 1 (Pak1). Pak1-DLC1 interaction plays an... | [
{
"id": "PMID-15193260_T3",
"type": "Cancer",
"text": [
"cancerous"
],
"offsets": [
[
79,
88
]
],
"normalized": []
},
{
"id": "PMID-15193260_T10",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
254,
... | [] | [] | [] |
PMC-3173373-caption-02 | PMC-3173373-caption-02 | [
{
"id": "PMC-3173373-caption-02__text",
"type": "caption",
"text": [
"Parameters derived from normalized averaged data across participants\n"
],
"offsets": [
[
0,
69
]
]
}
] | [] | [] | [] | [] |
PMID-10913166 | PMID-10913166 | [
{
"id": "PMID-10913166__text",
"type": "abstract",
"text": [
"TEL, a putative tumor suppressor, modulates cell growth and cell morphology of ras-transformed cells while repressing the transcription of stromelysin-1. \nTEL is a member of the ETS family of transcription factors that interacts with t... | [
{
"id": "PMID-10913166_T2",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
16,
21
]
],
"normalized": []
},
{
"id": "PMID-10913166_T3",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
44,
48
... | [] | [] | [] |
PMID-12484699 | PMID-12484699 | [
{
"id": "PMID-12484699__text",
"type": "abstract",
"text": [
"Regulation of transforming growth factor-beta signaling and vascular diseases.\nPURPOSE: Members of the transforming growth factor (TGF)-beta superfamily play critical roles in regulation of various cellular functions. Dysregulation of ... | [
{
"id": "PMID-12484699_T2",
"type": "Multi-tissue_structure",
"text": [
"vascular"
],
"offsets": [
[
60,
68
]
],
"normalized": []
},
{
"id": "PMID-12484699_T4",
"type": "Cell",
"text": [
"cellular"
],
"offsets": [
[
... | [] | [] | [] |
PMC-2727579-sec-09 | PMC-2727579-sec-09 | [
{
"id": "PMC-2727579-sec-09__text",
"type": "sec",
"text": [
"Conclusions and policy implications\nEarly postnatal home visit is one strategy for providing critical interventions to improve newborn survival. Given the compelling data in this study, we recommend that in developing countries, especi... | [] | [] | [] | [] |
PMC-2837610-sec-05 | PMC-2837610-sec-05 | [
{
"id": "PMC-2837610-sec-05__text",
"type": "sec",
"text": [
"1. Background\nThe United Republic of Tanzania, is among the many countries in sub-Saharan Africa facing a human resources crisis in its health sector, with a small and inequitably distributed health workforce [1] that shoulders a dispr... | [] | [] | [] | [] |
PMC-3267723-sec-02 | PMC-3267723-sec-02 | [
{
"id": "PMC-3267723-sec-02__text",
"type": "sec",
"text": [
"Results\n\n"
],
"offsets": [
[
0,
9
]
]
}
] | [] | [] | [] | [] |
PMID-16268479 | PMID-16268479 | [
{
"id": "PMID-16268479__text",
"type": "abstract",
"text": [
"Domain 5 of cleaved high molecular weight kininogen inhibits endothelial cell migration through Akt.\nDomain 5 (D5) of cleaved high molecular weight kininogen (HKa) inhibits angiogenesis in vivo and endothelial cell migration in vitro, ... | [
{
"id": "PMID-16268479_T2",
"type": "Cell",
"text": [
"endothelial cell"
],
"offsets": [
[
61,
77
]
],
"normalized": []
},
{
"id": "PMID-16268479_T6",
"type": "Cell",
"text": [
"endothelial cell"
],
"offsets": [
[
... | [] | [] | [] |
PMC-2719750-sec-10 | PMC-2719750-sec-10 | [
{
"id": "PMC-2719750-sec-10__text",
"type": "sec",
"text": [
"Quantitative reverse transcription PCR\nReverse transcription was performed using 0.2 mug of total RNA from muscle of 10 week-old and 19 month-old C57Bl6 mice (five animals per group), a Core kit (RT-RTCK-03, Eurogentec) according to ma... | [
{
"id": "PMC-2719750-sec-10_T1",
"type": "Tissue",
"text": [
"muscle"
],
"offsets": [
[
107,
113
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-11121230 | PMID-11121230 | [
{
"id": "PMID-11121230__text",
"type": "abstract",
"text": [
"RNA damage and inhibition of neoplastic endothelial cell growth: effects of human and amphibian ribonucleases.\nAngiogenesis defines the many steps involved in the growth and migration of endothelial cell-derived blood vessels. This pro... | [
{
"id": "PMID-11121230_T1",
"type": "Cell",
"text": [
"neoplastic endothelial cell"
],
"offsets": [
[
29,
56
]
],
"normalized": []
},
{
"id": "PMID-11121230_T4",
"type": "Cell",
"text": [
"endothelial cell"
],
"offsets": [
... | [] | [] | [] |
PMID-12610665 | PMID-12610665 | [
{
"id": "PMID-12610665__text",
"type": "abstract",
"text": [
"Arteriogenesis: the development and growth of collateral arteries.\nIn patients with atherosclerotic vascular diseases, collateral vessels bypassing major arterial obstructions have frequently been observed. This may explain why some pa... | [
{
"id": "PMID-12610665_T1",
"type": "Multi-tissue_structure",
"text": [
"collateral arteries"
],
"offsets": [
[
46,
65
]
],
"normalized": []
},
{
"id": "PMID-12610665_T3",
"type": "Multi-tissue_structure",
"text": [
"vascular"
]... | [] | [] | [] |
PMID-20978953 | PMID-20978953 | [
{
"id": "PMID-20978953__text",
"type": "abstract",
"text": [
"Role of stromal myofibroblasts in invasive breast cancer: stromal expression of alpha-smooth muscle actin correlates with worse clinical outcome. \nBACKGROUND: Recently, the desmoplastic reaction has been implicated as having an importa... | [
{
"id": "PMID-20978953_T1",
"type": "Cell",
"text": [
"stromal myofibroblasts"
],
"offsets": [
[
8,
30
]
],
"normalized": []
},
{
"id": "PMID-20978953_T2",
"type": "Cancer",
"text": [
"invasive breast cancer"
],
"offsets": [... | [] | [] | [] |
PMID-16165242 | PMID-16165242 | [
{
"id": "PMID-16165242__text",
"type": "abstract",
"text": [
"Enhancement of skin permeation of ketotifen by supersaturation generated by amorphous form of the drug.\nPressure sensitive adhesive (PSA) matrices containing amorphous ketotifen were prepared and evaluated for enhanced skin permeabilit... | [
{
"id": "PMID-16165242_T1",
"type": "Organ",
"text": [
"skin"
],
"offsets": [
[
15,
19
]
],
"normalized": []
},
{
"id": "PMID-16165242_T2",
"type": "Organ",
"text": [
"skin"
],
"offsets": [
[
219,
223
... | [] | [] | [] |
PMID-7474113 | PMID-7474113 | [
{
"id": "PMID-7474113__text",
"type": "abstract",
"text": [
"The inhibition of cultured myoblast differentiation by the simian virus 40 large T antigen occurs after myogenin expression and Rb up-regulation and is not exerted by transformation-competent cytoplasmic mutants. \nWe have investigated t... | [
{
"id": "PMID-7474113_T1",
"type": "Cell",
"text": [
"myoblast"
],
"offsets": [
[
27,
35
]
],
"normalized": []
},
{
"id": "PMID-7474113_T6",
"type": "Organism_substance",
"text": [
"cytoplasmic"
],
"offsets": [
[
... | [] | [] | [] |
PMID-17462601 | PMID-17462601 | [
{
"id": "PMID-17462601__text",
"type": "abstract",
"text": [
"An antibody directed against PDGF receptor beta enhances the antitumor and the anti-angiogenic activities of an anti-VEGF receptor 2 antibody.\nPlatelet-derived growth factor (PDGF) and its receptors (PDGFR) play important roles in tumo... | [
{
"id": "PMID-17462601_T2",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
65,
70
]
],
"normalized": []
},
{
"id": "PMID-17462601_T7",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
265,
2... | [] | [] | [] |
PMID-19369582 | PMID-19369582 | [
{
"id": "PMID-19369582__text",
"type": "abstract",
"text": [
"Characterization of the metabolic changes underlying growth factor angiogenic activation: identification of new potential therapeutic targets.\nAngiogenesis is a fundamental process to normal and abnormal tissue growth and repair, which... | [
{
"id": "PMID-19369582_T1",
"type": "Tissue",
"text": [
"tissue"
],
"offsets": [
[
204,
210
]
],
"normalized": []
},
{
"id": "PMID-19369582_T2",
"type": "Cell",
"text": [
"endothelial cells"
],
"offsets": [
[
2... | [] | [] | [] |
PMID-10589785 | PMID-10589785 | [
{
"id": "PMID-10589785__text",
"type": "abstract",
"text": [
"The antiangiogenic agent linomide inhibits the growth rate of von Hippel-Lindau paraganglioma xenografts to mice.\nThe aim of this study was to ascertain the potential usefulness of the antiangiogenic compound linomide for treatment of ... | [
{
"id": "PMID-10589785_T2",
"type": "Cancer",
"text": [
"von Hippel-Lindau paraganglioma xenografts"
],
"offsets": [
[
62,
104
]
],
"normalized": []
},
{
"id": "PMID-10589785_T5",
"type": "Cancer",
"text": [
"von Hippel-Lindau (VHL)... | [] | [] | [] |
PMID-12140030 | PMID-12140030 | [
{
"id": "PMID-12140030__text",
"type": "abstract",
"text": [
"Optimizing treatment of choroidal neovascularization feeder vessels associated with age-related macular degeneration.\nPURPOSE: To optimize the method of treating choroidal neovascularization (CNV) associated with age-related macular de... | [
{
"id": "PMID-12140030_T1",
"type": "Multi-tissue_structure",
"text": [
"choroidal"
],
"offsets": [
[
24,
33
]
],
"normalized": []
},
{
"id": "PMID-12140030_T2",
"type": "Multi-tissue_structure",
"text": [
"feeder vessels"
],
... | [] | [] | [] |
PMID-21596785 | PMID-21596785 | [
{
"id": "PMID-21596785__text",
"type": "abstract",
"text": [
"mirAct: a web tool for evaluating microRNA activity based on gene expression data.\nMicroRNAs (miRNAs) are critical regulators in the complex cellular networks. The mirAct web server (http://sysbio.ustc.edu.cn/software/mirAct) is a tool... | [
{
"id": "PMID-21596785_T1",
"type": "Multi-tissue_structure",
"text": [
"cellular networks"
],
"offsets": [
[
141,
158
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-11238633 | PMID-11238633 | [
{
"id": "PMID-11238633__text",
"type": "abstract",
"text": [
"IL-12 inhibition of endothelial cell functions and angiogenesis depends on lymphocyte-endothelial cell cross-talk.\nIn vivo IL-12-dependent tumor inhibition rests on the ability of IL-12 to activate a CD8-mediated cytotoxicity, inhibit ... | [
{
"id": "PMID-11238633_T2",
"type": "Cell",
"text": [
"endothelial cell"
],
"offsets": [
[
20,
36
]
],
"normalized": []
},
{
"id": "PMID-11238633_T3",
"type": "Cell",
"text": [
"lymphocyte"
],
"offsets": [
[
75... | [] | [] | [] |
PMID-10823148 | PMID-10823148 | [
{
"id": "PMID-10823148__text",
"type": "abstract",
"text": [
"Application of microsatellite PCR techniques in the identification of mixed up tissue specimens in surgical pathology.\nA fragment of tumour was erroneously mixed up with an endometrial biopsy. Micro-satellite polymerase chain reaction ... | [
{
"id": "PMID-10823148_T1",
"type": "Tissue",
"text": [
"tissue specimens"
],
"offsets": [
[
79,
95
]
],
"normalized": []
},
{
"id": "PMID-10823148_T2",
"type": "Cancer",
"text": [
"tumour"
],
"offsets": [
[
13... | [] | [] | [] |
PMID-16310808 | PMID-16310808 | [
{
"id": "PMID-16310808__text",
"type": "abstract",
"text": [
"Effect of thalidomide affecting VEGF secretion, cell migration, adhesion and capillary tube formation of human endothelial EA.hy 926 cells.\nAngiogenesis, new blood vessel formation, is a multistep process, precisely regulated by pro-an... | [
{
"id": "PMID-16310808_T3",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
48,
52
]
],
"normalized": []
},
{
"id": "PMID-16310808_T4",
"type": "Tissue",
"text": [
"capillary tube"
],
"offsets": [
[
77,
... | [] | [] | [] |
PMID-15811263 | PMID-15811263 | [
{
"id": "PMID-15811263__text",
"type": "abstract",
"text": [
"[Uncommon etiology of gastrointestinal bleeding: duodenal metastases from renal cell carcinoma].\nBecause of its unpredictable behavior, renal cell carcinoma is one of the most controversial neoplasms. On the one hand, patients frequent... | [
{
"id": "PMID-15811263_T1",
"type": "Organism_subdivision",
"text": [
"gastrointestinal"
],
"offsets": [
[
22,
38
]
],
"normalized": []
},
{
"id": "PMID-15811263_T2",
"type": "Cancer",
"text": [
"duodenal metastases"
],
"off... | [] | [] | [] |
PMID-16855378 | PMID-16855378 | [
{
"id": "PMID-16855378__text",
"type": "abstract",
"text": [
"Differential mechanisms of radiosensitization by 2-deoxy-D-glucose in the monolayers and multicellular spheroids of a human glioma cell line.\nIn vitro studies using monolayer cultures of human tumor cell lines have shown that 2-DG sele... | [
{
"id": "PMID-16855378_T2",
"type": "Cell",
"text": [
"monolayers"
],
"offsets": [
[
74,
84
]
],
"normalized": []
},
{
"id": "PMID-16855378_T3",
"type": "Cell",
"text": [
"multicellular spheroids"
],
"offsets": [
[
... | [] | [] | [] |
PMID-15725689 | PMID-15725689 | [
{
"id": "PMID-15725689__text",
"type": "abstract",
"text": [
"Role of thrombogenic factors in the development of atherosclerosis.\nHemostatic factors play a crucial role in generating thrombotic plugs at sites of vascular damage (atherothrombosis). However, whether hemostatic factors contribute di... | [
{
"id": "PMID-15725689_T3",
"type": "Pathological_formation",
"text": [
"thrombotic plugs"
],
"offsets": [
[
121,
137
]
],
"normalized": []
},
{
"id": "PMID-15725689_T4",
"type": "Multi-tissue_structure",
"text": [
"vascular"
],... | [] | [] | [] |
PMID-9206208 | PMID-9206208 | [
{
"id": "PMID-9206208__text",
"type": "abstract",
"text": [
"[Expression of metastasis suppressor gene nm23 in human hepatocellular carcinoma]. \nFor the purpose of investigating the relationship between the metastatic potential of the tumor as well as the expression of nm23-H1 mRNA, and for deter... | [
{
"id": "PMID-9206208_T3",
"type": "Cancer",
"text": [
"hepatocellular carcinoma"
],
"offsets": [
[
56,
80
]
],
"normalized": []
},
{
"id": "PMID-9206208_T4",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
... | [] | [] | [] |
PMID-18662848 | PMID-18662848 | [
{
"id": "PMID-18662848__text",
"type": "abstract",
"text": [
"Reversal of the malignant phenotype of ovarian cancer A2780 cells through transfection with wild-type PTEN gene. \nOBJECTIVE: PTEN (phosphatase and tensin homologue deleted on chromosome 10) is a tumor suppressor gene identified on huma... | [
{
"id": "PMID-18662848_T1",
"type": "Cell",
"text": [
"ovarian cancer A2780 cells"
],
"offsets": [
[
39,
65
]
],
"normalized": []
},
{
"id": "PMID-18662848_T5",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
... | [] | [] | [] |
PMID-2541348 | PMID-2541348 | [
{
"id": "PMID-2541348__text",
"type": "abstract",
"text": [
"Energy supply of the mitotic cell cycle and the Na+/H+-antiport in ascites tumors.\nThe activation of Na+ transport is due to the exchange of protons formed via glucose conversion into lactate for Na+, i.e., to the stimulation of the Na+... | [
{
"id": "PMID-2541348_T3",
"type": "Cancer",
"text": [
"ascites tumors"
],
"offsets": [
[
67,
81
]
],
"normalized": []
},
{
"id": "PMID-2541348_T13",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
402,
... | [] | [] | [] |
PMID-10771470 | PMID-10771470 | [
{
"id": "PMID-10771470__text",
"type": "abstract",
"text": [
"Active hair growth (anagen) is associated with angiogenesis.\nAfter the completion of skin development, angiogenesis, i.e., the growth of new capillaries from pre-existing blood vessels, is held to occur in the skin only under pathologi... | [
{
"id": "PMID-10771470_T1",
"type": "Multi-tissue_structure",
"text": [
"hair"
],
"offsets": [
[
7,
11
]
],
"normalized": []
},
{
"id": "PMID-10771470_T2",
"type": "Organ",
"text": [
"skin"
],
"offsets": [
[
85... | [] | [] | [] |
PMC-3256136-sec-15 | PMC-3256136-sec-15 | [
{
"id": "PMC-3256136-sec-15__text",
"type": "sec",
"text": [
"Discussion\nWe estimated the future acceptability of PrEP, examining the attitudes and preferences of potential user groups from different countries towards hypothetical and known PrEP attributes. Our results show that participants were... | [
{
"id": "PMC-3256136-sec-15_T1",
"type": "Organism_subdivision",
"text": [
"oral"
],
"offsets": [
[
2701,
2705
]
],
"normalized": []
}
] | [] | [] | [] |
PMC-3041925-caption-05 | PMC-3041925-caption-05 | [
{
"id": "PMC-3041925-caption-05__text",
"type": "caption",
"text": [
"Intact mass analysis of a mixed population of proteins. A mixture of the membrane protein KCNJ12, the soluble TEV protease used to cleave the fusion tag, and the membrane protein HVCN1, which occurred as a contaminant from an ea... | [
{
"id": "PMC-3041925-caption-05_T1",
"type": "Cellular_component",
"text": [
"membrane"
],
"offsets": [
[
73,
81
]
],
"normalized": []
},
{
"id": "PMC-3041925-caption-05_T2",
"type": "Cellular_component",
"text": [
"membrane"
],... | [] | [] | [] |
PMID-18835936 | PMID-18835936 | [
{
"id": "PMID-18835936__text",
"type": "abstract",
"text": [
"Angiogenesis associated with visceral and subcutaneous adipose tissue in severe human obesity.\nOBJECTIVE: The expansion of adipose tissue is linked to the development of its vasculature. However, the regulation of adipose tissue angiog... | [
{
"id": "PMID-18835936_T1",
"type": "Tissue",
"text": [
"visceral"
],
"offsets": [
[
29,
37
]
],
"normalized": []
},
{
"id": "PMID-18835936_T2",
"type": "Tissue",
"text": [
"subcutaneous adipose tissue"
],
"offsets": [
... | [] | [] | [] |
PMID-16101297 | PMID-16101297 | [
{
"id": "PMID-16101297__text",
"type": "abstract",
"text": [
"A novel conotoxin from Conus delessertii with posttranslationally modified lysine residues.\nA major peptide, de13a from the crude venom of Conus delessertii collected in the Yucatan Channel, Mexico, was purified. The peptide had a high... | [
{
"id": "PMID-16101297_T1",
"type": "Organism_substance",
"text": [
"venom"
],
"offsets": [
[
130,
135
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-20676141 | PMID-20676141 | [
{
"id": "PMID-20676141__text",
"type": "abstract",
"text": [
"Adenovirus 5 E1A enhances histone deacetylase inhibitors-induced apoptosis through Egr-1-mediated Bim upregulation. \nHistone deacetylase inhibitors (HDACi) are potent anti-cancer agents for variety of cancer types. Suberoylanilide hydr... | [
{
"id": "PMID-20676141_T7",
"type": "Cancer",
"text": [
"cancer"
],
"offsets": [
[
172,
178
]
],
"normalized": []
},
{
"id": "PMID-20676141_T8",
"type": "Cancer",
"text": [
"cancer"
],
"offsets": [
[
201,
... | [] | [] | [] |
PMID-12823209 | PMID-12823209 | [
{
"id": "PMID-12823209__text",
"type": "abstract",
"text": [
"Prognostic value of p53 protein expression and vascular endothelial growth factor expression in resected squamous cell carcinoma of the esophagus.\nThe most common genetic alterations found in a wide variety of cancers are p53 tumor sup... | [
{
"id": "PMID-12823209_T3",
"type": "Cancer",
"text": [
"squamous cell carcinoma"
],
"offsets": [
[
105,
128
]
],
"normalized": []
},
{
"id": "PMID-12823209_T4",
"type": "Organ",
"text": [
"esophagus"
],
"offsets": [
[... | [] | [] | [] |
PMID-10487573 | PMID-10487573 | [
{
"id": "PMID-10487573__text",
"type": "abstract",
"text": [
"External beam radiotherapy for subretinal neovascularization in age-related macular degeneration: is this treatment efficient?\nPURPOSE: Control of the natural course of subretinal neovascularization (SRNV) in age-related macular degene... | [
{
"id": "PMID-10487573_T1",
"type": "Immaterial_anatomical_entity",
"text": [
"subretinal"
],
"offsets": [
[
31,
41
]
],
"normalized": []
},
{
"id": "PMID-10487573_T2",
"type": "Tissue",
"text": [
"macular"
],
"offsets": [
... | [] | [] | [] |
PMID-7828172 | PMID-7828172 | [
{
"id": "PMID-7828172__text",
"type": "abstract",
"text": [
"Differential effects of carbachol on calcium entry and release in CHO cells expressing the m3 muscarinic receptor.\nCalcium signalling was examined in CHO-k1 cells that stably express the m3 subtype of the muscarinic receptor. The calciu... | [
{
"id": "PMID-7828172_T1",
"type": "Cell",
"text": [
"CHO cells"
],
"offsets": [
[
66,
75
]
],
"normalized": []
},
{
"id": "PMID-7828172_T2",
"type": "Cell",
"text": [
"CHO-k1 cells"
],
"offsets": [
[
150,
... | [] | [] | [] |
PMID-15202612 | PMID-15202612 | [
{
"id": "PMID-15202612__text",
"type": "abstract",
"text": [
"Novel insights into the pathogenesis of uric acid nephrolithiasis.\nPURPOSE OF REVIEW:\nThe factors involved in the pathogenesis of uric acid nephrolithiasis are well known. A low urinary pH is the most significant element in the genera... | [
{
"id": "PMID-15202612_T1",
"type": "Organism_substance",
"text": [
"urinary"
],
"offsets": [
[
178,
185
]
],
"normalized": []
},
{
"id": "PMID-15202612_T2",
"type": "Organism_substance",
"text": [
"urine"
],
"offsets": [
... | [] | [] | [] |
PMID-12884381 | PMID-12884381 | [
{
"id": "PMID-12884381__text",
"type": "abstract",
"text": [
"Stereoselective synthesis of 1-aminoalkanephosphonic acids with two chiral centers and their activity towards leucine aminopeptidase.\nThe stereoselective synthesis of 1-amino-2-alkylalkanephosphonic acids, namely, compounds bearing two... | [
{
"id": "PMID-12884381_T1",
"type": "Organ",
"text": [
"kidney"
],
"offsets": [
[
609,
615
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-21135106 | PMID-21135106 | [
{
"id": "PMID-21135106__text",
"type": "abstract",
"text": [
"The disintegrin-like and cysteine-rich domains of ADAM-9 mediate interactions between melanoma cells and fibroblasts. \nA characteristic of malignant cells is their capacity to invade their surrounding and to metastasize to distant orga... | [
{
"id": "PMID-21135106_T4",
"type": "Cell",
"text": [
"melanoma cells"
],
"offsets": [
[
86,
100
]
],
"normalized": []
},
{
"id": "PMID-21135106_T5",
"type": "Cell",
"text": [
"fibroblasts"
],
"offsets": [
[
10... | [] | [] | [] |
PMC-3012732-sec-15 | PMC-3012732-sec-15 | [
{
"id": "PMC-3012732-sec-15__text",
"type": "sec",
"text": [
"Reagents and antibodies\nMaxisorp strips (NunC, Roskilde, Denmark), GST-PNMA2 recombinant protein (Abnova, Taipei, Taiwan); 3,3',5,5-tetramethylbenzidine (TMB) + substrate (Dako, Glostrup, Denmark), Peroxidase with dakocytomation peroxi... | [] | [] | [] | [] |
PMID-6920468 | PMID-6920468 | [
{
"id": "PMID-6920468__text",
"type": "abstract",
"text": [
"Relationship of self-concept during late pregnancy to neonatal perception and parenting profile.\nThirty-one gravidas were studied to examine the relationship between a woman's feelings about herself during late pregnancy, her perception... | [] | [] | [] | [] |
PMID-15327827 | PMID-15327827 | [
{
"id": "PMID-15327827__text",
"type": "abstract",
"text": [
"Convergence of p53 and TGF-beta signaling networks. \np53 is a protein with many talents. One of the most fundamental is the ability to act as essential growth checkpoint that protects cells against cellular transformation. p53 does so ... | [
{
"id": "PMID-15327827_T4",
"type": "Cell",
"text": [
"cells"
],
"offsets": [
[
184,
189
]
],
"normalized": []
},
{
"id": "PMID-15327827_T5",
"type": "Cell",
"text": [
"cellular"
],
"offsets": [
[
198,
... | [] | [] | [] |
PMC-3052613-caption-01 | PMC-3052613-caption-01 | [
{
"id": "PMC-3052613-caption-01__text",
"type": "caption",
"text": [
"Modified radiology-guided percutaneous gastrostomy technique.\nA. 21G fine needle punctured localized collection of air, which was visible in collapsed stomach under fluoroscopy-guided gastrostomy. Needle tip is then gradually w... | [
{
"id": "PMC-3052613-caption-01_T1",
"type": "Organ",
"text": [
"stomach"
],
"offsets": [
[
151,
158
]
],
"normalized": []
},
{
"id": "PMC-3052613-caption-01_T2",
"type": "Organ",
"text": [
"stomach"
],
"offsets": [
[
... | [] | [] | [] |
PMID-10080451 | PMID-10080451 | [
{
"id": "PMID-10080451__text",
"type": "abstract",
"text": [
"Ventricular fibrillation due to long QT syndrome probably caused by clindamycin.\nProlongation of QT time interval may be provoked by a limited number of drugs, especially macrolide antibiotics. We describe a case of QT time interval pr... | [
{
"id": "PMID-10080451_T1",
"type": "Multi-tissue_structure",
"text": [
"Ventricular"
],
"offsets": [
[
0,
11
]
],
"normalized": []
},
{
"id": "PMID-10080451_T2",
"type": "Multi-tissue_structure",
"text": [
"ventricular"
],
... | [] | [] | [] |
PMID-19752254 | PMID-19752254 | [
{
"id": "PMID-19752254__text",
"type": "abstract",
"text": [
"Magnesium for treatment of asthma in children.\nQUESTION: Magnesium is considered adjuvant therapy for moderate to severe asthma exacerbations in adults, but can it be used to treat children? ANSWER: Magnesium seems to be beneficial in ... | [
{
"id": "PMID-19752254_T1",
"type": "Organism_subdivision",
"text": [
"epigastric"
],
"offsets": [
[
381,
391
]
],
"normalized": []
},
{
"id": "PMID-19752254_T2",
"type": "Organism_subdivision",
"text": [
"facial"
],
"offset... | [] | [] | [] |
PMC-3168770-caption-05 | PMC-3168770-caption-05 | [
{
"id": "PMC-3168770-caption-05__text",
"type": "caption",
"text": [
"Challenges to creating and implementing a perioperative glycemic control protocol.\n"
],
"offsets": [
[
0,
83
]
]
}
] | [] | [] | [] | [] |
PMC-2769146-sec-05 | PMC-2769146-sec-05 | [
{
"id": "PMC-2769146-sec-05__text",
"type": "sec",
"text": [
"3.2.\nCell line and culture\nDU145 (prostate cancer) cell line was used in this assay. DU145 was grown in DMEM/F-12 medium (Gibco BRL Life Technologies, San Diego, CA., USA) supplemented with 10% fetal calf serum and kept in a humidifie... | [
{
"id": "PMC-2769146-sec-05_T1",
"type": "Cell",
"text": [
"Cell line"
],
"offsets": [
[
5,
14
]
],
"normalized": []
},
{
"id": "PMC-2769146-sec-05_T2",
"type": "Cell",
"text": [
"DU145 (prostate cancer) cell line"
],
"offse... | [] | [] | [] |
PMID-1505125 | PMID-1505125 | [
{
"id": "PMID-1505125__text",
"type": "abstract",
"text": [
"NIH3T3 transfectant containing human K-ras oncogene shows enhanced metastatic activity after in vivo tumor growth or co-culture with fibroblasts. \nA clone of NIH3T3 transformant (H-3), obtained by transfecting genomic DNA of a human col... | [
{
"id": "PMID-1505125_T1",
"type": "Cell",
"text": [
"NIH3T3 transfectant"
],
"offsets": [
[
0,
19
]
],
"normalized": []
},
{
"id": "PMID-1505125_T4",
"type": "Cancer",
"text": [
"tumor"
],
"offsets": [
[
101,
... | [] | [] | [] |
PMID-2607031 | PMID-2607031 | [
{
"id": "PMID-2607031__text",
"type": "abstract",
"text": [
"Screening method for insecticidal activity using first instars of black blow fly (Diptera: Calliphoridae).\nA bioassay method suitable for rapid mass screening of fermentation and synthetic organic compounds for insecticidal activity is ... | [
{
"id": "PMID-2607031_T1",
"type": "Organism_substance",
"text": [
"serum"
],
"offsets": [
[
350,
355
]
],
"normalized": []
}
] | [] | [] | [] |
PMID-11587364 | PMID-11587364 | [
{
"id": "PMID-11587364__text",
"type": "abstract",
"text": [
"Oncogenic mechanisms of Evi-1 protein. \nAlthough Evi-1 is thought to promote growth or block differentiation in some cell types, its biological functions have not been elucidated. To explore the mechanisms underlying Evi-1-induced onco... | [
{
"id": "PMID-11587364_T3",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
117,
121
]
],
"normalized": []
},
{
"id": "PMID-11587364_T8",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
391,
395
... | [] | [] | [] |
PMID-9671543 | PMID-9671543 | [
{
"id": "PMID-9671543__text",
"type": "abstract",
"text": [
"Acylase I-catalyzed deacetylation of N-acetyl-L-cysteine and S-alkyl-N-acetyl-L-cysteines.\nThe aminoacylase that catalyzes the hydrolysis of N-acetyl-L-cysteine (NAC) was identified as acylase I after purification by column chromatograp... | [
{
"id": "PMID-9671543_T1",
"type": "Organism_substance",
"text": [
"kidney cytosol"
],
"offsets": [
[
273,
287
]
],
"normalized": []
},
{
"id": "PMID-9671543_T2",
"type": "Organ",
"text": [
"kidney"
],
"offsets": [
[
... | [] | [] | [] |
PMID-16773443 | PMID-16773443 | [
{
"id": "PMID-16773443__text",
"type": "abstract",
"text": [
"Fluoro-Jade B staining following zymosan microinjection into the spinal cord white matter.\n1. The fluorescein derivate Fluoro-Jade B (FJB), which primarily labels dead or dying neurons, was used to study the acute focal inflammation in... | [
{
"id": "PMID-16773443_T1",
"type": "Multi-tissue_structure",
"text": [
"spinal cord white matter"
],
"offsets": [
[
65,
89
]
],
"normalized": []
},
{
"id": "PMID-16773443_T2",
"type": "Cell",
"text": [
"neurons"
],
"offsets... | [] | [] | [] |
PMID-19953879 | PMID-19953879 | [
{
"id": "PMID-19953879__text",
"type": "abstract",
"text": [
"[Reconstruction of hepatic artery in adult to adult living donor liver transplantation in 104 patients].\nOBJECTIVE:\nTo report the experience of hepatic artery reconstruction with adult-to-adult living donor liver transplantation (ALDL... | [
{
"id": "PMID-19953879_T1",
"type": "Multi-tissue_structure",
"text": [
"hepatic artery"
],
"offsets": [
[
19,
33
]
],
"normalized": []
},
{
"id": "PMID-19953879_T2",
"type": "Organ",
"text": [
"liver"
],
"offsets": [
... | [] | [] | [] |
PMID-10978899 | PMID-10978899 | [
{
"id": "PMID-10978899__text",
"type": "abstract",
"text": [
"Urokinase receptor: a molecular organizer in cellular communication.\nIn a variety of cell types, the glycolipid-anchored urokinase receptor (uPAR) is colocalized pericellularly with components of the plasminogen activation system and e... | [
{
"id": "PMID-10978899_T2",
"type": "Cell",
"text": [
"cellular"
],
"offsets": [
[
45,
53
]
],
"normalized": []
},
{
"id": "PMID-10978899_T3",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
85,
89
... | [] | [] | [] |
PMID-2314900 | PMID-2314900 | [
{
"id": "PMID-2314900__text",
"type": "abstract",
"text": [
"Overexpression confers an oncogenic potential upon the eph gene. \nThe eph gene encodes a putative receptor tyrosine kinase for an as yet unknown ligand. Some human cancer cells have been found to overexpress eph mRNAs without gene ampli... | [
{
"id": "PMID-2314900_T5",
"type": "Cell",
"text": [
"cancer cells"
],
"offsets": [
[
164,
176
]
],
"normalized": []
},
{
"id": "PMID-2314900_T7",
"type": "Cell",
"text": [
"NIH3T3 cells"
],
"offsets": [
[
264,... | [] | [] | [] |
PMC-3245051-caption-01 | PMC-3245051-caption-01 | [
{
"id": "PMC-3245051-caption-01__text",
"type": "caption",
"text": [
"The growth in the number of database publications per year. Each bar shows the number of research articles with the keyword 'database' appearing in the article title in the given year. The count only covers articles indexed in P... | [] | [] | [] | [] |
PMID-2704697 | PMID-2704697 | [
{
"id": "PMID-2704697__text",
"type": "abstract",
"text": [
"Early post-mortem metabolism and muscle shortening in the Pectoralis major muscle of broiler chickens.\nThree experiments were conducted to examine the effects of sodium pentobarbital (SP), iodoacetate (IO), tubocurarine (TC), and surgic... | [
{
"id": "PMID-2704697_T1",
"type": "Organ",
"text": [
"muscle"
],
"offsets": [
[
33,
39
]
],
"normalized": []
},
{
"id": "PMID-2704697_T2",
"type": "Organ",
"text": [
"muscle"
],
"offsets": [
[
75,
81
... | [] | [] | [] |
PMID-16398404 | PMID-16398404 | [
{
"id": "PMID-16398404__text",
"type": "abstract",
"text": [
"The differential regulation of human telomerase reverse transcriptase and vascular endothelial growth factor may contribute to the clinically more aggressive behavior of p63-positive breast carcinomas.\np63, a p53 homologue, is a myoepi... | [
{
"id": "PMID-16398404_T4",
"type": "Cancer",
"text": [
"p63-positive breast carcinomas"
],
"offsets": [
[
170,
200
]
],
"normalized": []
},
{
"id": "PMID-16398404_T8",
"type": "Cell",
"text": [
"myoepithelial cell"
],
"offs... | [] | [] | [] |
PMID-19236257 | PMID-19236257 | [
{
"id": "PMID-19236257__text",
"type": "abstract",
"text": [
"Aflibercept (AVE0005): an alternative strategy for inhibiting tumour angiogenesis by vascular endothelial growth factors.\nBACKGROUND: Aberrant angiogenesis is a landmark feature in cancer, which is important for proliferation, growth a... | [
{
"id": "PMID-19236257_T3",
"type": "Cancer",
"text": [
"tumour"
],
"offsets": [
[
62,
68
]
],
"normalized": []
},
{
"id": "PMID-19236257_T5",
"type": "Cancer",
"text": [
"cancer"
],
"offsets": [
[
181,
... | [] | [] | [] |
PMID-9778569 | PMID-9778569 | [
{
"id": "PMID-9778569__text",
"type": "abstract",
"text": [
"Glucose and lactate metabolism in C6 glioma cells: evidence for the preferential utilization of lactate for cell oxidative metabolism.\n13C and 1H nuclear magnetic resonance spectroscopy (NMR) was used to investigate the metabolism of L-... | [
{
"id": "PMID-9778569_T3",
"type": "Cell",
"text": [
"C6 glioma cells"
],
"offsets": [
[
34,
49
]
],
"normalized": []
},
{
"id": "PMID-9778569_T5",
"type": "Cell",
"text": [
"cell"
],
"offsets": [
[
108,
... | [] | [] | [] |
PMID-17960624 | PMID-17960624 | [
{
"id": "PMID-17960624__text",
"type": "abstract",
"text": [
"Ovarian cancers overexpress the antimicrobial protein hCAP-18 and its derivative LL-37 increases ovarian cancer cell proliferation and invasion.\nThe role of the pro-inflammatory peptide, LL-37, and its pro-form, human cationic antimicr... | [
{
"id": "PMID-17960624_T1",
"type": "Cancer",
"text": [
"Ovarian cancers"
],
"offsets": [
[
0,
15
]
],
"normalized": []
},
{
"id": "PMID-17960624_T4",
"type": "Cell",
"text": [
"ovarian cancer cell"
],
"offsets": [
[
... | [] | [] | [] |
PMID-17662274 | PMID-17662274 | [
{
"id": "PMID-17662274__text",
"type": "abstract",
"text": [
"Subcellular localisation of BAG-1 and its regulation of vitamin D receptor-mediated transactivation and involucrin expression in oral keratinocytes: implications for oral carcinogenesis. \nIn oral cancers, cytoplasmic BAG-1 overexpressi... | [
{
"id": "PMID-17662274_T4",
"type": "Cell",
"text": [
"oral keratinocytes"
],
"offsets": [
[
129,
147
]
],
"normalized": []
},
{
"id": "PMID-17662274_T5",
"type": "Organism_subdivision",
"text": [
"oral"
],
"offsets": [
... | [] | [] | [] |
PMID-9840923 | PMID-9840923 | [
{
"id": "PMID-9840923__text",
"type": "abstract",
"text": [
"Tumors of the retinal pigment epithelium metastasize to inguinal lymph nodes and spleen in tyrosinase-related protein 1/SV40 T antigen transgenic mice. \nThe pigment epithelium of the retina (RPE) is derived from the optic cup and is ess... | [
{
"id": "PMID-9840923_T1",
"type": "Cancer",
"text": [
"Tumors"
],
"offsets": [
[
0,
6
]
],
"normalized": []
},
{
"id": "PMID-9840923_T2",
"type": "Tissue",
"text": [
"retinal pigment epithelium"
],
"offsets": [
[
... | [] | [] | [] |
PMC-3087566-caption-11 | PMC-3087566-caption-11 | [
{
"id": "PMC-3087566-caption-11__text",
"type": "caption",
"text": [
"Representative time histories of the estimated SatO2 levels of normal cortex (black) and tumor (grey) from all six patients.\n"
],
"offsets": [
[
0,
125
]
]
}
] | [
{
"id": "PMC-3087566-caption-11_T1",
"type": "Multi-tissue_structure",
"text": [
"cortex"
],
"offsets": [
[
70,
76
]
],
"normalized": []
},
{
"id": "PMC-3087566-caption-11_T2",
"type": "Cancer",
"text": [
"tumor"
],
"offsets... | [] | [] | [] |
PMID-2418866 | PMID-2418866 | [
{
"id": "PMID-2418866__text",
"type": "abstract",
"text": [
"Retinal revascularisation in diabetic retinopathy.\nThe case history of a 33-year-old diabetic patient who has had diabetes for 24 years is presented. When first seen in 1975 he had bilateral proliferative retinopathy with new vessels in... | [
{
"id": "PMID-2418866_T2",
"type": "Multi-tissue_structure",
"text": [
"vessels"
],
"offsets": [
[
226,
233
]
],
"normalized": []
},
{
"id": "PMID-2418866_T3",
"type": "Tissue",
"text": [
"capillary"
],
"offsets": [
[
... | [] | [] | [] |
PMID-17432972 | PMID-17432972 | [
{
"id": "PMID-17432972__text",
"type": "abstract",
"text": [
"The relationship between brain activity and peak grip force is modulated by corticospinal system integrity after subcortical stroke.\nIn healthy human subjects, the relative contribution of cortical regions to motor performance varies w... | [
{
"id": "PMID-17432972_T1",
"type": "Organ",
"text": [
"brain"
],
"offsets": [
[
25,
30
]
],
"normalized": []
},
{
"id": "PMID-17432972_T2",
"type": "Multi-tissue_structure",
"text": [
"cortical regions"
],
"offsets": [
... | [] | [] | [] |
PMID-3492269 | PMID-3492269 | [
{
"id": "PMID-3492269__text",
"type": "abstract",
"text": [
"Growth state-dependent regulation of protein kinase C in normal and transformed murine cells. \nWe determined whether growth state can influence the action of protein kinase C by measuring protein kinase C activity in growing and station... | [
{
"id": "PMID-3492269_T3",
"type": "Cell",
"text": [
"cells"
],
"offsets": [
[
87,
92
]
],
"normalized": []
},
{
"id": "PMID-3492269_T6",
"type": "Cell",
"text": [
"cells"
],
"offsets": [
[
275,
280
... | [] | [] | [] |
PMID-10890377 | PMID-10890377 | [
{
"id": "PMID-10890377__text",
"type": "abstract",
"text": [
"The value of serum S-100beta and interleukins as tumour markers in advanced melanoma. \nRecently serum S-100beta has shown promise as a tumour marker in melanoma; however, its use as a prognostic marker in the advanced stage needs to be... | [
{
"id": "PMID-10890377_T1",
"type": "Organism_substance",
"text": [
"serum"
],
"offsets": [
[
13,
18
]
],
"normalized": []
},
{
"id": "PMID-10890377_T4",
"type": "Cancer",
"text": [
"tumour"
],
"offsets": [
[
4... | [] | [] | [] |
End of preview. Expand
in Data Studio
Dataset Card for AnatEM
The extended Anatomical Entity Mention corpus (AnatEM) consists of 1212 documents (approx. 250,000 words) manually annotated to identify over 13,000 mentions of anatomical entities. Each annotation is assigned one of 12 granularity-based types such as Cellular component, Tissue and Organ, defined with reference to the Common Anatomy Reference Ontology.
Citation Information
@article{pyysalo2014anatomical,
title={Anatomical entity mention recognition at literature scale},
author={Pyysalo, Sampo and Ananiadou, Sophia},
journal={Bioinformatics},
volume={30},
number={6},
pages={868--875},
year={2014},
publisher={Oxford University Press}
}
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