2021 San Francisco 49ers season

The 2021 season is the San Francisco 49ers' 72nd season in the National Football League and their fifth under the head coach Kyle Shanahan. They finished the regular season with 10 wins and 7 lossses, and advanced to the playoffs as the 6th seed. In the playoffs, they upset the 3rd-seeded Dallas Cowboys (who had 12 wins and 5 losses) and the 1-seed Green Bay Packers (13 wins and 4 losses), but lost in the NFC title game to division rival Los Angeles Rams.
Regular season.
Schedule.
The 49ers' 2021 schedule was announced on May 12.
Note: Intra-division opponents are in bold text.