Cosimo I de' Medici, Grand Duke of Tuscany

Cosimo I de' Medici (12 June 1519 – 21 April 1574) was Duke of Florence from 1537 to 1574 and then the first Medici Grand Duke of Tuscany from 1569. He was the son of Giovanni dalle Bande Nere and Maria Salviati. 
Marriage and family.
In 1539, he married Eleonora di Toledo (1522–1562). She died, with her sons Giovanni and Garzia, in 1562, aged forty. All three of them died from malaria while traveling to Pisa.
Before his first marriage, Cosimo fathered an illegitimate daughter with an unknown woman:
With Eleonora, Cosimo fathered eleven children:
After Eleonora's death in 1562, Cosimo fathered two children with his mistress Eleonora degli Albrizzi:
In 1570, Cosimo married Camilla Martelli: