and the fourth panel with a vertical line and a horizontal line. A response to recognizing the meme was "Is this Loss?" The meme saw a resurgence around 2017. Brian Feldman declared it as "the Internet's Longest-Running Miscarriage 'Joke. In 2016, the podcast Reply All discussed the strip in their analysis of a variant of "Loss" that was used as a joke about the results in the 2016 United States presidential election. The hosts described it as a pattern that viewers would never recognize unless they were already familiar with it, and said that because the strip was stark and iconic, that also made it easy to parody. On June 2, 2018, the tenth anniversary of "Loss", the original strip was replaced by an edit of the comic titled "Found". While almost all of the comic remained the same, in the last panel Ethan instead looks at the audience with a smirk on his face. A day later, the original strip was restored with no explanation for the replacement. Julia Alexander from Polygon considered "Found" to be an acknowledgement of the status "Loss" had achieved as a meme, comparing the evolution of the strip to Pepe the Frog. Similarly, on June 2, 2019, the strip was replaced by an edit of the comic titled "Cross". This edit replaced the last panel with one where the birth was successful, however the child's face is a minimalist version of the comic itself. References External links The original strip 2008 in webcomics 2008 works Internet memes introduced in 2008 Medicine and health in fiction