"estimated without reference to their Chinese context."" (Cooper & Sivin 1973: 203). They selected 8 widely used human drugs from the 37 listed in ""Bencao gangmu"" chapter 52: human hair, nails, teeth, milk, blood, semen, saliva, and bone. For each substance, Cooper and Sivin first analyzed the ""Bencao gangmu"" information about drug preparation and use, and then commented on the known chemical composition of the human drug and other ingredients in the prescriptions. Cooper & Sivin (1973: 259-60, Table 8.1) applied the criteria of clinical pharmacology to analyze the possible medicinal value of the ""Bencao gangmu"" pharmacopeia's human drug prescriptions"
"from ""soma"", body, it thus makes a desmosome a ""binding body"". Desmosomes are one of the stronger cell-to-cell adhesion types and are found in tissue that experience intense mechanical stress, such as cardiac muscle tissue, bladder tissue, gastrointestinal mucosa, and epithelia. Desmosomes are composed of desmosome-intermediate filament complexes (DIFC), which is a network of cadherin proteins, linker proteins and keratin intermediate filaments. The DIFCs can be broken into three regions: the extracellular core region, or desmoglea, the outer dense plaque, or ODP, and the inner dense plaque, or IDP. The extracellular core region, approximately 34 nm in length, contains desmoglein"
"Hard tissue Hard tissue (also termed calcified tissue) is tissue which is mineralized and has a firm intercellular matrix. The hard tissues of humans are bone, tooth enamel, dentin, and cementum. The term is in contrast to soft tissue. Bone is a rigid organ that constitutes part of the vertebral skeleton. Bones support and protect the various organs of the body, produce red and white blood cells, store minerals and also enable mobility. Bone tissue is a type of dense connective tissue. Bones come in a variety of shapes and sizes and have a complex internal and external structure. They"
"is the thickest of the human body, measuring up to 8 mm in thickness, and contains approximately 100.000 hairs. Hair lines make scalp reconstruction difficult because the hair lines must be respected to attain a satisfying aesthetic result. The subCutis is a layer of fat, enclosed in compartments formed by rigid fibrous septa. Their inelasticity prevents bleeding vessels from collapsing and retracting under the skin to achieve haemostasis. All large blood vessels and nerves of the scalp are located in this layer. The next layer is the galea Aponeurotica, which separates the underlying bone and the overlying layers. The large"
"of the pulp canal. Hard tissue Hard tissue (also termed calcified tissue) is tissue which is mineralized and has a firm intercellular matrix. The hard tissues of humans are bone, tooth enamel, dentin, and cementum. The term is in contrast to soft tissue. Bone is a rigid organ that constitutes part of the vertebral skeleton. Bones support and protect the various organs of the body, produce red and white blood cells, store minerals and also enable mobility. Bone tissue is a type of dense connective tissue. Bones come in a variety of shapes and sizes and have a complex internal"
"Toxic heavy metal A toxic heavy metal is any relatively dense metal or metalloid that is noted for its potential toxicity, especially in environmental contexts. The term has particular application to cadmium, mercury, lead and arsenic, all of which appear in the World Health Organization's list of 10 chemicals of major public concern. Other examples include manganese, chromium, cobalt, nickel, copper, zinc, selenium, silver, antimony and thallium. Heavy metals are found naturally in the earth. They become concentrated as a result of human caused activities and can enter plant, animal, and human tissues via inhalation, diet, and manual handling. Then,"
"cases the sclerites are fused to various degrees. Thorax The thorax or chest (from the Greek θώραξ ""thorax"" ""breastplate, cuirass, corslet"" via ) is a part of the anatomy of humans and various other animals located between the neck and the abdomen. The thorax includes the thoracic cavity and the thoracic wall. It contains organs including the heart, lungs, and thymus gland, as well as muscles and various other internal structures. Many diseases may affect the chest, and one of the most common symptoms is chest pain. In humans and other hominids, the thorax is the chest region of the"
"organ of the body. In humans, it accounts for about 12 to 15 percent of total body weight and covers 1.5-2m of surface area. The human skin (integument) is composed of at least two major layers of tissue: the epidermis and dermis. (The hypodermis or subcutaneous layer is not part of the skin.) The epidermis is the outermost layer, providing the initial barrier to the external environment. Beneath this, the dermis comprises two sections, the papillary and reticular layers, and contains connective tissues, vessels, glands, follicles, hair roots, sensory nerve endings, and muscular tissue. The deepest layer, the hypodermis, is"
"Collagen Collagen is the main structural protein in the extracellular space in the various connective tissues in the body. As the main component of connective tissue, it is the most abundant protein in mammals, making 25% to 35% of the whole-body protein content. Collagen consists of amino acids wound together to form triple-helices l of elongated fibrils. It is mostly found in fibrous tissues such as tendons, ligaments and skin. Depending upon the degree of mineralization, collagen tissues may be either rigid (bone) or compliant (tendon) or have a gradient from rigid to compliant (cartilage). It is also abundant in"
"Corpus callosum The corpus callosum (Latin for ""tough body""), also callosal commissure, is a wide, thick, nerve tract consisting of a flat bundle of commissural fibers, beneath the cerebral cortex in the brain. The corpus callosum is only found in placental mammals. It spans part of the longitudinal fissure, connects the left and right cerebral hemispheres, enabling communication between them. It is the largest white matter structure in the human brain, about ten centimetres in length and consisting of 200–300 million axonal projections. A number of separate nerve tracts, classed as subregions, of the corpus callosum connect different parts of"
"the softest known substances, and diamond, the hardest naturally occurring substance. It bonds readily with other small atoms, including other carbon atoms, and is capable of forming multiple stable covalent bonds with suitable multivalent atoms. Carbon is known to form almost ten million different compounds, a large majority of all chemical compounds. Carbon also has the highest sublimation point of all elements. At atmospheric pressure it has no melting point, as its triple point is at and , so it sublimes at about 3,900 K. Graphite is much more reactive than diamond at standard conditions, despite being more thermodynamically stable,"
"Thorax The thorax or chest (from the Greek θώραξ ""thorax"" ""breastplate, cuirass, corslet"" via ) is a part of the anatomy of humans and various other animals located between the neck and the abdomen. The thorax includes the thoracic cavity and the thoracic wall. It contains organs including the heart, lungs, and thymus gland, as well as muscles and various other internal structures. Many diseases may affect the chest, and one of the most common symptoms is chest pain. In humans and other hominids, the thorax is the chest region of the body between the neck and the abdomen, along"
"Tooth enamel Tooth enamel is one of the four major tissues that make up the tooth in humans and many other animals, including some species of fish. It makes up the normally visible part of the tooth, covering the crown. The other major tissues are dentin, cementum, and dental pulp. It is a very hard, white to off-white, highly mineralised substance that acts as a barrier to protect the tooth but can become susceptible to degradation, especially by acids from food and drink. Enamel is the hardest substance in the human body and contains the highest percentage of minerals, 96%,"
"g in men, ~2.3 g in women Of the 94 naturally occurring chemical elements, 60 are listed in the table above. Of the remaining 34, it is not known how many occur in the human body. Most of the elements needed for life are relatively common in the Earth's crust. Aluminium, the third most common element in the Earth's crust (after oxygen and silicon), serves no function in living cells, but is harmful in large amounts. Transferrins can bind aluminium. The composition of the human body is expressed in terms of chemicals: The composition of the human body can be"
"Keratin Keratin () is one of a family of fibrous structural proteins. It is the key structural material making up hair, horns, claws, hooves, and the outer layer of human skin. Keratin is also the protein that protects epithelial cells from damage or stress. Keratin is extremely insoluble in water and organic solvents. Keratin monomers assemble into bundles to form intermediate filaments, which are tough and form strong unmineralized epidermal appendages found in reptiles, birds, amphibians, and mammals. The only other biological matter known to approximate the toughness of keratinized tissue is chitin. Keratin derives from Greek ' from '"
"made up of various salts. Enamel is the hardest substance in the human body and contains the highest percentage of minerals, 96%, with water and organic material composing the rest. The primary mineral is hydroxyapatite, which is a crystalline calcium phosphate. Enamel is formed on the tooth while the tooth is developing within the gum, before it erupts into the mouth. Once fully formed, it does not contain blood vessels or nerves. Remineralisation of teeth can repair damage to the tooth to a certain degree but damage beyond that cannot be repaired by the body. The maintenance and repair of"
"(""proper"", ""unalterable"", ""unbreakable"") and sometimes called adamant, diamond is the hardest known naturally occurring material, scoring 10 on the Mohs scale of mineral hardness. Diamond is extremely strong owing to the structure of its carbon atoms, where each carbon atom has four neighbors joined to it with covalent bonds. The material boron nitride, when in a form structurally identical to diamond (zincblende structure), is nearly as hard as diamond; a currently hypothetical material, beta carbon nitride, may also be as hard or harder in one form. It has been shown that some diamond aggregates having nanometer grain size are harder"
"considered a physiological minimum for human males. Irrespective of the location from which they are obtained, the fat cells in humans are composed almost entirely of pure triglycerides with an average density of about 0.9 kilograms per litre. Most modern body composition laboratories today use the value of 1.1 kilograms per litre for the density of the “fat free mass”, a theoretical tissue composed of 72% water (density = 0.993), 21% protein (density = 1.340) and 7% mineral (density = 3.000) by weight. With a well engineered weighing system, body density can be determined with great accuracy by completely submerging"
"organisms. Composition of the human body Body composition may be analyzed in terms of molecular type e.g., water, protein, connective tissue, fats (or lipids), hydroxylapatite (in bones), carbohydrates (such as glycogen and glucose) and DNA. In terms of tissue type, the body may be analyzed into water, fat, muscle, bone, etc. In terms of cell type, the body contains hundreds of different types of cells, but notably, the largest ""number"" of cells contained in a human body (though not the largest mass of cells) are not human cells, but bacteria residing in the normal human gastrointestinal tract. Almost 99% of"
"Bone marrow Bone marrow is a semi-solid tissue which may be found within the spongy or cancellous portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production or hematopoiesis. It is composed of hematopoietic cells, marrow adipose tissue, and supportive stromal cells. In adult humans, bone marrow is primarily located in the ribs, vertebrae, sternum, and bones of the pelvis. On average, bone marrow constitutes 4% of the total body mass of humans; in an adult having 65 kilograms of mass (143 lb), bone marrow typically accounts for approximately . Human marrow"
"aggregated diamond nanorods, which is harder than bulk diamond and is currently the hardest (~150 GPa) material known. Superhard material A superhard material is a material with a hardness value exceeding 40 gigapascals (GPa) when measured by the Vickers hardness test. They are highly incompressible solids with high electron density and high bond covalency. As a result of their unique properties, these materials are of great interest in many industrial areas including, but not limited to, abrasives, polishing and cutting tools and wear-resistant and protective coatings. Diamond is the hardest known material to date, with a Vickers hardness in the"
"Composition of the human body Body composition may be analyzed in terms of molecular type e.g., water, protein, connective tissue, fats (or lipids), hydroxylapatite (in bones), carbohydrates (such as glycogen and glucose) and DNA. In terms of tissue type, the body may be analyzed into water, fat, muscle, bone, etc. In terms of cell type, the body contains hundreds of different types of cells, but notably, the largest ""number"" of cells contained in a human body (though not the largest mass of cells) are not human cells, but bacteria residing in the normal human gastrointestinal tract. Almost 99% of the"
"in platinum ores. Osmium is the least abundant stable element in the earth's crust, found only in minor traces in platinum ores. Hassium is produced only in nuclear reactors and has never been observed in nature nor isolated in pure form. Iron is an essential nutrient for all living organisms, from archaea to humans. It is a major component in hemoglobin, a protein that makes blood red and transfers oxygen to muscles, and is also found in many other proteins. Ruthenium, osmium, and hassium have no known role in the human body. Group 8 element Group 8 is a group"
"skin is the second largest organ in the human body (the inside of the small intestine is 15 to 20 times larger). For the average adult human, the skin has a surface area of between 1.5-2.0 square meters (16.1-21.5 sq ft.). The thickness of the skin varies considerably over all parts of the body, and between men and women and the young and the old. An example is the skin on the forearm which is on average 1.3 mm in the male and 1.26 mm in the female. The average square inch (6.5 cm²) of skin holds 650 sweat glands,"
"The human body contains about 12 mg of manganese, mostly in the bones. The soft tissue remainder is concentrated in the liver and kidneys. In the human brain, the manganese is bound to manganese metalloproteins, most notably glutamine synthetase in astrocytes. Manganese is also important in photosynthetic oxygen evolution in chloroplasts in plants. The oxygen-evolving complex (OEC) is a part of photosystem II contained in the thylakoid membranes of chloroplasts; it is responsible for the terminal photooxidation of water during the light reactions of photosynthesis, and has a metalloenzyme core containing four atoms of manganese. To fulfill this requirement, most"
"and target), electrodes in gas tungsten arc welding, superalloys, and radiation shielding. Tungsten's hardness and high density give it military applications in penetrating projectiles. Tungsten compounds are also often used as industrial catalysts. Tungsten is the only metal from the third transition series that is known to occur in biomolecules that are found in a few species of bacteria and archaea. It is the heaviest element known to be essential to any living organism. Tungsten interferes with molybdenum and copper metabolism and is somewhat toxic to animal life. In its raw form, tungsten is a hard steel-grey metal that is"
"respiratory system and skin, called chronic beryllium disease or berylliosis. The body's immune system recognises the beryllium as foreign particles and mounts an attack against them, usually in the lungs where they are breathed in. This can cause fever, fatigue, weakness, night sweats and difficulty in breathing. Boron (B) is the chemical element with atomic number 5, occurring as B and B. At standard temperature and pressure, boron is a trivalent metalloid that has several different allotropes. Amorphous boron is a brown powder formed as a product of many chemical reactions. Crystalline boron is a very hard, black material with"
"by the body, as is the case with many examples of ingested metal objects. With sufficient force (as in firing of bullets), a foreign body can become lodged into nearly any tissue. One of the most common locations for a foreign body is the alimentary tract. It is possible for foreign bodies to enter the tract from the mouth, or from the rectum. Both children and adults experience problems caused by foreign objects getting stuck in their bodies. Young children, in particular, are naturally curious and may intentionally put shiny objects, such as coins or button batteries, into their mouths."
"HAZMAT Class 8 Corrosive substances A corrosive material is a liquid or solid that causes full thickness destruction of human skin at the site of contact within a specified period of time. A liquid that has a severe corrosion rate on steel or aluminum based on the criteria in 49CFR 173.137(c)(2) is also a corrosive material. 454 kg (1001 lbs) or more gross weight of a corrosive material. Although the corrosive class includes both acids and bases, the hazardous materials load and segregation chart does not make any reference to the separation of various incompatible corrosive materials from each other."
"element in the human body by weight, about equal in abundance to potassium, and slightly greater than sodium and chlorine. A human body contains about 140 grams of sulfur. In plants and animals, the amino acids cysteine and methionine contain most of the sulfur, and the element is present in all polypeptides, proteins, and enzymes that contain these amino acids. In humans, methionine is an essential amino acid that must be ingested. However, save for the vitamins biotin and thiamine, cysteine and all sulfur-containing compounds in the human body can be synthesized from methionine. The enzyme sulfite oxidase is needed"
"Test (biology) In biology, a test is the hard shell of some spherical marine animals, notably sea urchins and microorganisms such as testate foraminiferans, radiolarians, and testate amoebae. The anatomical term ""test"" derives from the Latin ""testa"" (which means a rounded bowl, amphora or bottle). It is distinct from the term ""test"" as in ""examination"", which derives from ""testis"", related to the idea of testimony. The test is a skeletal structure, made of hard material such as calcium carbonate, silica, chitin or composite materials. As such, it allows the protection of the internal organs and the attachment of soft flesh."
"Superhard material A superhard material is a material with a hardness value exceeding 40 gigapascals (GPa) when measured by the Vickers hardness test. They are highly incompressible solids with high electron density and high bond covalency. As a result of their unique properties, these materials are of great interest in many industrial areas including, but not limited to, abrasives, polishing and cutting tools and wear-resistant and protective coatings. Diamond is the hardest known material to date, with a Vickers hardness in the range of 70–150 GPa. Diamond demonstrates both high thermal conductivity and electrically insulating properties and much attention has"
"of other neurons, muscles, or glands at their termination points. A nervous system emerges from the assemblage of neurons that are connected to each other. In vertebrates, the nervous system can be split into two parts, the central nervous system (brain and spinal cord), and the peripheral nervous system. In many species — including all vertebrates — the nervous system is the most complex organ system in the body, with most of the complexity residing in the brain. The human brain alone contains around one hundred billion neurons and one hundred trillion synapses; it consists of thousands of distinguishable substructures,"