"Non-communicable disease A non-communicable disease (NCD) is a disease that is not transmissible directly from one person to another. NCDs include Parkinson's disease, autoimmune diseases, strokes, most heart diseases, most cancers, diabetes, chronic kidney disease, osteoarthritis, osteoporosis, Alzheimer's disease, cataracts, and others. NCDs may be chronic or acute. Most are non-infectious, although there are some non-communicable infectious diseases, such as parasitic diseases in which the parasite's life cycle does not include direct host-to-host transmission. NCDs are the leading cause of death globally. In 2012, they caused 68% of all deaths (38 million) up from 60% in 2000. About half were"
"denied by NHS England's Freedom of Information Officer in October 2015. At the time NHS England also asked one of the authors to corroborate Hunt's figures who refused to do so, stating that it would interfere with the peer review of the unpublished paper; in response they reframed the figure as being based on earlier studies on its website in August 2015. In October 2015, Hunt was accused by the editor of ""The BMJ"" Fiona Godlee of repeatedly misrepresenting a study published in the journal in the same year by Freemantle et al. on the weekend effect to parliament and"
"2013 highlighting particular hospitals with more than one such event. NHS Improvement has produced monthly and cumulative annual reports since 2015, when the definition of what constitutes a Never Event in the NHS also changed to require not only actual patient harm but also the potential for significant actual harm. Annual counts have therefore increased, and comparing recent with older data is misleading. The definition continues to undergo more minor change. A provisional report for the 10 month period April 1st 2017 to 31st Jan 2018 acknowledged 393 never events within NHS England, including 172 wrong site surgeries, 97 retained"
"risk of preventable death."" In May 2015 it was reported that Luke Henry and Stephanie Rudwick, the parents of a child suffering from Tuberous Sclerosis were trying to sell their home in Brighton to raise the money to pay for treatment for their daughter Bethany who has tumours on her brain, kidneys and liver and suffers from up to fifty epileptic fits a day. It authorises and pays for treatment of narcolepsy with sodium oxybate by means of individual funding requests on the basis of exceptional circumstances. In May 2016 the High Court ordered NHS England to provide funding to"
"highlighted by NHS England as having 3 of the 148 reported never events in the period from April to September 2013. The trust was one of five to benefit from a five-year, £12.5m programme announced by Jeremy Hunt in July 2015 to bring in Virginia Mason Medical Center to assist English hospitals using their clinical engagement and culture tools including the Patient Safety Alert System and electronic dashboard. Hunt said “The achievements at Virginia Mason over the past decade are truly inspirational and I’m delighted they will now help NHS staff to learn the lessons that made their hospital one"
"neurodegeneration. In 2014, she was elected van Geest Professor of Clinical Neurosciences at the University of Cambridge and in 2017 was awarded the Cambridge Centre of UK Dementia Research Institute of which she is director. She is Honorary Consultant Neurologist at Addenbrooke's Hospital, with a specialist interest in dementia. Her background is in modelling prion diseases in mice, looking at mechanisms of neurotoxicity and developing new therapeutic approaches. Her group have shown that early synaptic changes in mice with prion disease can be reversed, resulting in recovery of synaptic and cognitive function and behavioural deficits, long term neuroprotection, and life"
"of neurodevelopmental disorder. On 4 November 2009, Lord Hameed, the charity's president, tabled a motion in the House of Lords asking the Government what measures have been taken to prevent cerebral palsy which now costs the NHS £4 billion every year. The total annual cost of brain disorders (covering 19 groups of disorders) has been estimated to be €798 billion for the EU alone. The charity's most recent research projects include: Little Foundation The Little Foundation is a London-based charity operating internationally. Named in honour of William Little, the English surgeon who described what became known as 'Little's disease', a"
"in the UK loses their life to meningitis and everyone affected gets the support they need. Without a vaccine to protect against all types of meningitis there is still much to do and Meningitis Now continues to counter the misconceptions that meningitis is a disease of the past and that it only affects babies and young children - in fact, anyone of any age can contract meningitis. Meningitis Now's goals remain to save lives and prevent disability through improving prevention and rapid diagnosis and rebuilding futures and improving quality of life through increased recognition of the impact of meningitis and"
"successes, word of mouth, and media coverage, the penny stock newsletter grew rapidly, selling over 30,000 subscriptions by May 27, 2009. In his mid to late teens, Peter Leeds began feeling the effects of his multiple sclerosis, which had not yet been diagnosed. He experienced unexplained bouts of numbness in his limbs, dizziness, fatigue, and weakness. The symptoms would occur each year, and last for weeks at a time, before he would return to normal. Despite dramatically worsening symptoms with each progressive attack, it was not until 2005 that Peter Leeds received the official diagnosis based on two rounds of"
"of the accident and emergency department. In August 2014, Brett and Naghemeh King took their 5-year-old son Ashya from the hospital, where he was being treated for medulloblastoma, without doctor's knowledge. Brett King claimed this was in order to avoid the proposed treatment of chemotherapy and photon beam radiation therapy which he feared would result in brain damage to Ashya. The family's preferred treatment was proton beam therapy which is currently unavailable in the United Kingdom except through an NHS overseas referral programme to fund treatment in America or Europe for specific indications. Although clinicians at Southampton felt proton beam"
"The first follow-up study was published in ""PLoS ONE"" in 2010; it was conducted in the UK and found no evidence of XMRV in CFS patients. The publication sparked what ""The Economist"" dubbed a transatlantic ""fight"". Supporters of the two teams traded accusations of conflicts of interest, technical sloppiness, and failure to care about patients. The Reno Gazette-Journal reported that Mikovits stated the ""PLoS ONE"" study team biased their study so as to not find the virus in its samples, and that Mikovits ""suspected insurance companies in the United Kingdom are behind attempts to sully the findings of the Reno"
"has received coverage including the April 2015 edition of the Alzheimer's Society's magazine ""Living with Dementia"" and BBC Radio 4's ""You and Yours"" consumer programme on 29 April 2015. In March 2016 it was announced that the campaign had been endorsed by the NHS and that trusts would be encouraged ""to consider facilitating an approach whereby the families and carers of people with dementia can support them fully while they are in hospital"". John's Campaign John's Campaign is a campaign for extended visiting rights for family carers of patients with dementia in hospitals in the United Kingdom, founded on 30"
"considerably heavier than the plastic ones used later, especially when wet. This was not the first case of a footballer's illness or death (particularly in the form of Alzheimer's or dementia type symptoms) being connected to heading old-fashioned footballs, another example being the former Tottenham Hotspur captain Danny Blanchflower who died of Alzheimer's disease in December 1993. A verdict of ""death by industrial injury"" was recorded. In 2014, the ""Justice for Jeff"" campaign was launched, calling for an independent inquiry into a possible link between degenerative brain disease and heading footballs. Subsequently, he was confirmed as the first British footballer"
"understanding of inflammatory mechanisms lead to improved outcome in bacterial meningitis?"" 2008: Dr Susan O’Connell, Southampton General Hospital, UK – ""Lyme neuroborreliosis – the greatest controversy of the day"" 2007: Professor Peter Kennedy, University of Glasgow, UK – ""Varicella Zoster Virus infections of the nervous system"" The course has been reviewed positively by the British Medical Journal and in Advances in Clinical Neuroscience and Rehabilitation Liverpool Neurological Infectious Diseases Course The Liverpool Neurological Infectious Diseases Course (or NeuroID) is an annual two-day course aimed at medical professionals and students with an interest in neurological infectious diseases. The course is organised"
"by NHS England as having 3 of 148 reported never events in the period from April to September 2013. The trust was one of 26 responsible for half of the national growth in patients waiting more than four hours in accident and emergency over the 2014/5 winter. Anna Dugdale, the Chief Executive, resigned in June 2015 after a Care Quality Commission report alleged a “bullying culture” at the trust was coming from the highest level of management. More than 150 consultants met the hospital chairman to raise concerns about how issues raised in the report were dealt with. It ended"
"of mechanisms of action are needed before new classes of therapeutic agents can be developed. Narcolepsy is an underdiagnosed condition in the general population. This is partly because its severity varies, so it can be mistaken for other illnesses very easily. Some people with narcolepsy do not suffer from loss of muscle control. In 2015, it was reported that the British Department of Health was paying for sodium oxybate medication at a cost of £12,000 a year for 80 people who are taking legal action over problems linked to the use of the Pandemrix swine flu vaccine. Sodium oxybate is"
"Peter St George-Hyslop Peter Henry St George-Hyslop, OC MD, FRS, FRSC, FRCPC, (born July 10, 1953) is a British and Canadian medical scientist, neurologist and molecular geneticist who is known for his research into neurodegenerative diseases. He has identified a number of key genes that are responsible for nerve cell degeneration and early-onset forms of Alzheimer's disease. St George-Hyslop's father, Noel St George Hyslop was a renowned scientist who worked on Foot and Mouth Disease virus. Since 2007 St George-Hyslop has headed an Alzheimer's disease research program as Professor of Experimental Neuroscience at the University of Cambridge. Educated at Wellington"
"the deaths of at least 49 benefit claimants (not all of whom were claiming ""disability"" benefits). The department was compelled to publish their findings in May 2016 after a campaign by ""Disability News Service"". The conclusions of the heavily redacted reports included: A study published in the ""Journal of Epidemiology and Community Health"" in November 2015 found an independent correlation between the deployment of the Incapacity Benefit reassessment programme in England and an increase in reported mental health problems, higher levels of antidepressant prescribing and 590 additional suicides. The DWP responded by pointing out that association does not imply causation:"
"that a brain scan showed no evidence that Ashya had a brain tumour. A 2015 report reviewing the case stated that King's parents' decision to deny their child chemotherapy had reduced his chances of survival by 30 percent. Reviews also called on health providers to do a better job communicating with parents. In 2016, following the publication of a prospective phase II trial the NHS decided it will pay for children with medulloblastoma to travel abroad to receive proton therapy. In 2018 and MRI scans, conducted in Southampton, showed Ashya to be free of cancer. Ashya King case The Ashya"
"a legacy paper, which welcomed the recent MRC initiative, but felt that there has been far too much emphasis in the past on psychological research, with insufficient attention to biomedical research, and that it is vital that further biomedical research be undertaken to help discover a cause and more effective forms of management for this disease. There has been controversy surrounding psychologically-oriented models of the disease and behavioral treatments conducted in the UK. On 29 October 2015 the National Institutes of Health declared its intent to increase research on ME/CFS. The NIH Clinical Center was to study individuals with ME/CFS,"
"can be concluded into four aspects: genetic mutation, protein misfolding, intracellular mechanisms and programmed cell death. Main classes of neurodegeneritive diseases are Alzheimer's disease, Parkinson's disease, Huntington's disease and Amyotrophic lateral sclerosis. Different neurodegenerative diseases have different causes and are not well studied until now. There is no clear cure for such diseases but some efforts have been made to research deeper into them. The 10th Global College of Neuroproetction and Neuroregeneration Annual Conference together with the International Association of Neurorestoratology VI was held to discuss on neurorestoration, neuroprotection and neuroregeneration in various clinical neurodegenerative diseases like Alzheimer's, Parkinson's, Huntington's"
"Northern Ireland. It is also a member of the International Huntington Alliance. Huntington's Disease Association The Huntington's Disease Association (HDA) is a charity that supports people in England and Wales affected by the genetic neurodegenerative brain condition Huntington's disease (HD). The HDA was founded in 1986 and is based in Liverpool. It supports a network of regional care advisors who offer care and support to people with and at risk of Huntington's disease and their families. The HDA also has a research programme that supports scientific and social research into HD. It has worked to establish and support a network"
"commissioner on July 5, 2017. In 2016, Orridge received media attention after saying there was no conclusive link between playing in the CFL and developing Chronic traumatic encephalopathy (CTE), a progressive degenerative disease of the brain found in athletes (and others) with a history of repetitive brain trauma. At the time, there was a $200 million class-action lawsuit in Canada's courts on behalf of CFL players seeking monetary compensation for CTE. A document released by the British Journal of Sport Medicine in April 2017 discussing treatment of concussions stated: ""There's still no scientific evidence of a cause-and-effect relationship between concussions"
"that the paper had been revised following lengthy reviews by two faculty members from institutions different from the author's. In 2013, another MDPI journal, ""Entropy"", published a review paper claiming glyphosate may be the most important factor in the development of obesity, depression, attention deficit hyperactivity disorder, autism, Alzheimer's disease, Parkinson's disease, multiple sclerosis, cancer, and infertility. The paper itself does not contain any primary research results. It was criticized as pseudo-science by the popular science magazine ""Discover"". With regard to the same controversial study, Jeffrey Beall has rhetorically asked, ""Will MDPI publish anything for money?"". In 2016, another MDPI"
"neurodegenerative disorders such as Alzheimer's disease, developmental dyslexia, and schizophrenia. However, it is important to note that none of these findings has been clinically translated to help individual patients. She has received funding from the Wellcome Trust, MRC and the Health Foundation. Julie Williams (scientist) Julie Williams (born c. 1957) is Professor of Neuropsychological Genetics at Cardiff University and the Chief Scientific Adviser for Wales since 2013. She is one of the world's leading contributors to Alzheimer's research. She was born in Merthyr Tydfil, Wales, and grew up in Cefn Coed. Attended Vaynor and Penderyn Grammar School. She went on"
"studies by German physician David Bardens, Lanka did not accept the findings, forcing Bardens to appeal in court. The legal case ended with the ruling that Lanka was to pay the prize. The case received wide international coverage that prompted many to comment on it, including neurologist, well-known skeptic and science-based medicine advocate Steven Novella, who called Lanka ""a crank"". Other names include morbilli, rubeola, red measles, and English measles. In May 2015, the journal ""Science"", published a report in which researchers found that the measles infection can leave a population at increased risk for mortality from other diseases for"
"The Motor Neurone Disease Association criticised the show for misleading viewers about a cure for motor neuron disease. The charity was contacted by several people who were upset about the storyline, and they requested a response from the BBC. The ""Group Animal"" storyline contributed to ""Holby City""'s nomination in the Soap and Continuing Drama category at the Royal Television Society Awards in March 2018. The episodes won the Best Drama Storyline category at the 2018 ""Inside Soap"" Awards, under the title ""The hospital shooting"". Group Animal ""Group Animal"" is a two-part episode of the British medical drama ""Holby City"" that"
"Neuronal ceroid lipofuscinosis Neuronal ceroid lipofuscinosis (NCL) is the general name for a family of at least eight genetically separate neurodegenerative disorders that result from excessive accumulation of lipopigments (lipofuscin) in the body's tissues. These lipopigments are made up of fats and proteins. Their name comes from the word stem ""lipo-"", which is a variation on ""lipid"" or ""fat"", and from the term ""pigment"", used because the substances take on a greenish-yellow color when viewed under an ultraviolet light microscope. These lipofuscin materials build up in neuronal cells and many organs, including the liver, spleen, myocardium, and kidneys. The classic"
"King's Department of Neurology/Neurosciences. There is a large outpatient movement disorder clinic, specialising in multidisciplinary team management of Parkinson's disease, dystonia, progressive supranuclear palsy, and related diseases. It is one of only five centres in the European Union designated a ""Centre of Excellence"" by the National Parkinson Foundation. In 1995 the hospital established the UK's first specialist Motor Neurone Disease Care & Research Centre, a model of care which has since been reproduced at other centres throughout the United Kingdom. The hospital is also home to the only dedicated diverticular disease clinic. King's College Hospital NHS Foundation Trust King's College"
"adverse reactions in the United Kingdom and had never been tested for effectiveness. However the vice-president of the AMA, Trevor Mudge, refuted her claims, pointing out that meningococcal disease is extremely dangerous and that ""Vaccination really is the only strategy for this condition that is likely to work"". He said the vaccine had been extensively tested and contrary to Dorey's claims had been found to be safe and highly effective in the UK. During an online debate covering meningococcal vaccination in 2005, Australian infectious disease specialist Peter McIntyre warned parents ""not to be fooled by the limited and biased information"
"Technology Committee of the United Kingdom House of Commons recommended that homeopathy should no longer be a beneficiary of NHS funding due its lack of scientific credibility; funding ceased in 2017. In March 2015, the National Health and Medical Research Council of Australia published an information paper on Homeopathy. The main findings of the report were 'there are no health conditions for which there is reliable evidence that homeopathy is effective"". Reactions to the report sparked world headlines which suggested that the NHMRC had found that homeopathy is not effective for all conditions. In 2018, Australian pharmacies ignored recommendations for"
"John's Campaign John's Campaign is a campaign for extended visiting rights for family carers of patients with dementia in hospitals in the United Kingdom, founded on 30 November 2014 by the writers Nicci Gerrard and Julia Jones. In February 2014 Nicci Gerrard's father Dr John Gerrard, aged 86, spent five weeks in hospital for the treatment of leg ulcers. He suffered from Alzheimer's disease and his family's visiting was severely restricted because of a combination of normal ""visiting hours"" and an infectious outbreak. His condition deteriorated dramatically while he was in hospital; having previously been living well with Alzheimers he"
"Honours for services to the NHS and improving care. Her award was presented to her at Buckingham Palace by the Prince of Wales, in June 2015. Also in 2015, she was made an honorary Doctor of Science by London South Bank University. In 2016, Granger received a special achievement award from the BMJ, honouring her for her work on the ""Hello, my name is"" campaign. Kate Granger Kate Miriam Granger (31 October 1981 – 23 July 2016) was an English geriatrician and campaigner for better patient care. In 2011 she was diagnosed with desmoplastic small-round-cell tumor (DSRCT), a type of"