"Posterior segment of eyeball The posterior segment or posterior cavity is the back two-thirds of the eye that includes the anterior hyaloid membrane and all of the optical structures behind it: the vitreous humor, retina, choroid, and optic nerve. The portion of the posterior segment visible during ophthalmoscopy (or fundoscopy) is sometimes referred to as the posterior pole, or fundus. Some ophthalmologists specialize in the treatment and management of posterior segment disorders and diseases. In some animals, the retina contains a reflective layer (the tapetum lucidum) which increases the amount of light each photosensitive cell perceives, allowing the animal to"
"of the external eye muscles) may be less complete, however. Tenon's capsule The fascia bulbi (also known as the capsule of Tenon and the bulbar sheath) is a thin membrane which envelops the eyeball from the optic nerve to the limbus, separating it from the orbital fat and forming a socket in which it moves. Its inner surface is smooth, and is separated from the outer surface of the sclera by the periscleral lymph space. This lymph space is continuous with the subdural and subarachnoid cavities, and is traversed by delicate bands of connective tissue which extend between the fascia"
"Retina The retina is the innermost, light-sensitive layer, or ""coat"", of shell tissue of the eye of most vertebrates and some molluscs. The optics of the eye create a focused two-dimensional image of the visual world on the retina, which translates that image into electrical neural impulses to the brain to create visual perception, the retina serving much the same function as film or a CCD in a camera. The retina consists of several layers of neurons interconnected by synapses. The neural retina refers to the three layers of neural cells (photo receptor cells, bipolar cells, and ganglion cells) within"
"into a single nerve fiber. Furthermore, the nerves are large and relatively accessible. This made it possible for electrophysiologists to record the nervous response to light stimulation easily, and to observe visual phenomena such as lateral inhibition working at the cellular level. More recently, behavioral experiments have investigated the functions of visual perception in ""Limulus"". Habituation and classical conditioning to light stimuli have been demonstrated, as has the use of brightness and shape information by males when recognizing potential mates. The retinula (literally, ""small retina"") cells of the ommatidium of the compound eye contain areas from which membranous organelles of"
"not receiving a light signal. Outer plexiform layer The outer plexiform layer (external plexiform layer) is a layer of neuronal synapses in the retina of the eye. It consists of a dense network of synapses between dendrites of horizontal cells from the inner nuclear layer, and photoreceptor cell inner segments from the outer nuclear layer. It is much thinner than the inner plexiform layer, where amacrine cells synapse with retinal ganglion cells. The synapses in the outer plexiform layer are between the rod cell endings or cone cell branched foot plates and horizontal cells. Unlike in most systems, rod and"
"light from its surroundings onto a light-sensitive membrane in the back of the eye, called the retina. The retina is actually part of the brain that is isolated to serve as a transducer for the conversion of light into neuronal signals. Based on feedback from the visual system, the lens of the eye adjusts its thickness to focus light on the photoreceptive cells of the retina, also known as the rods and cones, which detect the photons of light and respond by producing neural impulses. These signals are processed via complex feedforward and feedback processes by different parts of the"
"eyes and in the deep brain the ciliary photoreceptor cells. The ciliary photoreceptor cells express a ciliary opsin, which is a photopigment maximally sensitive to UV-light (""λ"" = 383 nm). Thus, the ciliary photoreceptor cells react on UV-light and make the larvae swimming down gravitactically. The gravitaxis here is countered by phototaxis, which makes the larvae swimming up to the light coming from the surface. Phototaxis is mediated by the rhabdomeric eyes. The eyes express at least three opsins (at least in the older larvae), and one of them is maximally sensitive to cyan light (""λ"" = 483 nm) so"
"optic nerve. The retina comprises numerous pigment cells and photoreceptors; the latter are easily modified flagellated cells, whose flagellum membranes carry a photosensitive pigment on their surface. The rhabdomeric eyes of the Onychophora are thought to be homologous with the median ocelli of arthropods; this would imply that the last common ancestor of arthropods bore only median ocelli. However, the innervation shows that the homology is limited: the eyes of Onychophora form behind the antenna, whereas the opposite is true in arthropods. Both sexes possess pairs of gonads, opening via a channel called a gonoduct into a common genital opening,"
"from the neural tissue of the retina. The outer layer is highly pigmented, continuous with the retinal pigment epithelium, and constitutes the cells of the dilator muscle. This double membrane is often considered continuous with the retina and a rudiment of the embryological correspondent to the retina. The inner layer is unpigmented until it reaches the iris, where it takes on pigment. The retina ends at the ora serrata. The parasympathetic innervation of the ciliary body is the most clearly understood. Presynaptic parasympathetic signals that originate in the Edinger-Westphal nucleus are carried by cranial nerve III (the oculomotor nerve) and"
"cells in the retina to nerve fibres of the optic nerve. When rods and cones are stimulated by light, they connect through adjoining cells within the retina to send an electrical signal to the optic nerve fibres. The optic nerves send off impulses through these fibres to the brain. The pigment molecules used in the eye are various, but can be used to define the evolutionary distance between different groups, and can also be an aid in determining which are closely related – although problems of convergence do exist. Opsins are the pigments involved in photoreception. Other pigments, such as"
"stage. Recently Ader and colleagues in Dublin showed, using the electron microscope, that transplanted photoreceptors formed synaptic connections. In 2012, Sebastian Seung and his laboratory at MIT have launched EyeWire, an online Citizen science game where players trace neurons in the retina. The goals of the EyeWire project are to identify specific cell types within the known broad classes of retinal cells, and to map the connections between neurons in the retina, which will help to determine how vision works. Retina The retina is the innermost, light-sensitive layer, or ""coat"", of shell tissue of the eye of most vertebrates and"
"that may generate micro bubble that can clog micro vessels. Retinal nerve fiber layer The retinal nerve fiber layer (RNFL) or nerve fiber layer, stratum opticum, is formed by the expansion of the fibers of the optic nerve; it is thickest near the optic disc, gradually diminishing toward the ora serrata. As the nerve fibers pass through the lamina cribrosa sclerae they lose their medullary sheaths and are continued onward through the choroid and retina as simple axis-cylinders. When they reach the internal surface of the retina they radiate from their point of entrance over this surface grouped in bundles,"
"main phyla. In most vertebrates and some molluscs, the eye works by allowing light to enter and project onto a light-sensitive panel of cells, known as the retina, at the rear of the eye. The cone cells (for colour) and the rod cells (for low-light contrasts) in the retina detect and convert light into neural signals for vision. The visual signals are then transmitted to the brain via the optic nerve. Such eyes are typically roughly spherical, filled with a transparent gel-like substance called the vitreous humour, with a focusing lens and often an iris; the relaxing or tightening of"
"nerve via micro electrodes. Photoreceptors are the specialized neurons that convert photons into electrical signals. They are part of the retina, a multilayer neural structure about 200 um thick that lines the back of the eye. The processed signal is sent to the brain through the optical nerve. If any part of this pathway is damaged blindness can occur. Blindness can result from damage to the optical pathway (cornea, aqueous humor, crystalline lens, and vitreous). This can happen as a result of accident or disease. The two most common retinal degenerative diseases that result in blindness secondary to photoreceptor loss"
"the lens which controls the amount of light entering the eye. At the centre of the iris is the pupil, the variable circular area through which the light passes into the eye. The retina is a relatively smooth curved multi-layered structure containing the photosensitive rod and cone cells with the associated neurons and blood vessels. The density of the photoreceptors is critical in determining the maximum attainable visual acuity. Humans have about 200,000 receptors per mm, but the house sparrow has 400,000 and the common buzzard 1,000,000. The photoreceptors are not all individually connected to the optic nerve, and the"
"field terminate more superiorly, to the cuneus. The optic nerve transmits all visual information including brightness perception, color perception and contrast (visual acuity). It also conducts the visual impulses that are responsible for two important neurological reflexes: the light reflex and the accommodation reflex. The light reflex refers to the constriction of both pupils that occurs when light is shone into either eye; the accommodation reflex refers to the swelling of the lens of eye that occurs when one looks at a near object as in reading (lens adjusts to near vision). The eye's blind spot is a result of"
"Tenon's capsule The fascia bulbi (also known as the capsule of Tenon and the bulbar sheath) is a thin membrane which envelops the eyeball from the optic nerve to the limbus, separating it from the orbital fat and forming a socket in which it moves. Its inner surface is smooth, and is separated from the outer surface of the sclera by the periscleral lymph space. This lymph space is continuous with the subdural and subarachnoid cavities, and is traversed by delicate bands of connective tissue which extend between the fascia and the sclera. The fascia is perforated behind by the"
"Lamina cribrosa sclerae The nerve fibers forming the optic nerve exit the eye posteriorly through a hole in the sclera that is occupied by a mesh-like structure called the lamina cribrosa. It is formed by a multilayered network of collagen fibers that insert into the scleral canal wall. The nerve fibers that comprise the optic nerve run through pores formed by these collagen beams. In humans, a central retinal artery is located slightly off-center in nasal direction. The lamina cribrosa is thought to help maintain the pressure gradient between the inside of the eye and the surrounding tissue. Being structurally"
"the membrane as far as its center, drawing it toward the tympanic cavity. The lateral surface of the membrane is thus concave. The most depressed aspect of this concavity is termed the umbo (). Sensory innervation of the external surface of the tympanic membrane is supplied mainly by the auriculotemporal nerve, a branch of the mandibular nerve (cranial nerve V), with contributions from the auricular branch of the vagus nerve (cranial nerve X), the facial nerve (cranial nerve VII), and possibly the glossopharyngeal nerve (cranial nerve IX). The inner surface of the tympanic membrane is innervated by the glossopharyngeal nerve."
"Bowman's membrane The Bowman's membrane (Bowman's layer, anterior limiting lamina, anterior elastic lamina) is a smooth, acellular, nonregenerating layer, located between the superficial epithelium and the stroma in the cornea of the eye. It is composed of strong, randomly oriented collagen fibrils in which the smooth anterior surface faces the epithelial basement membrane and the posterior surface merges with the collagen lamellae of the corneal stroma proper. In adult humans, Bowman's membrane is 8-12 μm thick. With ageing, this layer becomes thinner. The Bowman's layer, in mammals, is found only in primates. The function of the Bowman's membrane remains unclear"
"are shaded by pigment cells forming a cup. The photoreceptor cells do not synapse directly onto ciliated cells or muscle cells but onto inter-neurons of a processing center. This way the information of all four eye cups can be compared and a low resolution image of four pixels can be created telling the larvae where the light is coming from. This way the larva does not need to scan its environment by rotating. This is an adaption for living on the bottom of the sea the life style of the nectochaete larva while scanning rotation is more suited for living"
"Retinal nerve fiber layer The retinal nerve fiber layer (RNFL) or nerve fiber layer, stratum opticum, is formed by the expansion of the fibers of the optic nerve; it is thickest near the optic disc, gradually diminishing toward the ora serrata. As the nerve fibers pass through the lamina cribrosa sclerae they lose their medullary sheaths and are continued onward through the choroid and retina as simple axis-cylinders. When they reach the internal surface of the retina they radiate from their point of entrance over this surface grouped in bundles, and in many places arranged in plexuses. Most of the"
"The retina is where a group of light-sensing cells, called photoreceptors are located. There are two types of photoreceptors: rods and cones. Rods are sensitive to dim light and cones are better able to transduce bright light. Photoreceptors connect to bipolar cells, which induce action potentials in retinal ganglion cells. These retinal ganglion cells form a bundle at the optic disc, which is a part of the optic nerve. The two optic nerves from each eye meet at the optic chiasm, where nerve fibers from each nasal retina cross which results in the right half of each eye's visual field"
"Zonule of Zinn The zonule of Zinn () (Zinn's membrane, ciliary zonule) (after Johann Gottfried Zinn) is a ring of fibrous strands forming a zonule (little band) that connects the ciliary body with the crystalline lens of the eye. These fibers are sometimes collectively referred to as the suspensory ligaments of the lens, as they act like suspensory ligaments. The ciliary epithelial cells of the eye probably synthesize portions of the zonules. The zonule of Zinn is split into two layers: a thin layer, which lines the hyaloid fossa, and a thicker layer, which is a collection of zonular fibers."
"membrane called the conjunctiva. It helps lubricate the eye by producing mucus and tears. It also contributes to immune surveillance and helps to prevent the entrance of microbes into the eye. In many animals, including humans, eyelids wipe the eye and prevent dehydration. They spread tears on the eyes, which contains substances which help fight bacterial infection as part of the immune system. Some species have a nictitating membrane for further protection. Some aquatic animals have a second eyelid in each eye which refracts the light and helps them see clearly both above and below water. Most creatures will automatically"
"Orbital septum The orbital septum (Palpebral fascia) is a membranous sheet that acts as the anterior boundary of the orbit. It extends from the orbital rims to the eyelids. It forms the fibrous portion of the eyelids. In the upper eyelid, the orbital septum blends with the tendon of the levator palpebrae superioris, and in the lower eyelid with the tarsal plate. When the eyes are closed, the whole orbital opening is covered by the septum and tarsi. Medially it is thin, and, becoming separated from the medial palpebral ligament, attaches to the lacrimal bone at its posterior crest. The"
"the dolphin effectively blind, but the eye may still serve as a light receptor. The retina contains a densely packed receptor layer, a very thin bipolar and ganglion cell layer, and a tiny optic nerve (with only a few hundred optic fibers) that are sufficient for the retina to act as a light-gathering component. The dense pigmentation in the skin overlying the eye prevents light from reaching the retina from any entrance except for a pinhole sphincter-like structure. This structure is controlled by a cone-shaped muscle layer that extends from the posterior eye orbit to the overlying eye skin layer."
"tapetum lucidum. Enhanced intensity range is achieved via technological means through the use of an image intensifier, gain multiplication CCD, or other very low-noise and high-sensitivity array of photodetectors. All photoreceptor cells in the vertebrate eye contain molecules of photoreceptor protein which is a combination of the protein photopsin in color vision cells, rhodopsin in night vision cells, and retinal (a small photoreceptor molecule). Retinal undergoes an irreversible change in shape when it absorbs light; this change causes an alteration in the shape of the protein which surrounds the retinal, and that alteration then induces the physiological process which results"
"In the human eye, light enters the pupil and is focused on the retina by the lens. Light-sensitive nerve cells called rods (for brightness), cones (for color) and non-imaging ipRGC (intrinsincally photosensitive retinal ganglion cells) react to the light. They interact with each other and send messages to the brain. The rods and cones enable vision. The ipRGCs enable entrainment to the Earth's 24-hour cycle, resizing of the pupil and acute suppression of the pineal hormone melatonin. The retina contains three forms of photosensitive cells, two of them important to vision, rods and cones, in addition to the subset of"
"called the retina. The retina converts patterns of light into neuronal signals. The lens of the eye focuses light on the photoreceptive cells of the retina, which detect the photons of light and respond by producing neural impulses. These signals are processed in a hierarchical fashion by different parts of the brain, from the retina to the lateral geniculate nucleus, to the primary and secondary visual cortex of the brain. Signals from the retina can also travel directly from the retina to the Superior colliculus. The human eye is an organ which reacts to light for several purposes. As a"
"The vertebrate retina has ten distinct layers. From closest to farthest from the vitreous body: These layers can be grouped into 4 main processing stages: photoreception; transmission to bipolar cells; transmission to ganglion cells, which also contain photoreceptors, the photosensitive ganglion cells; and transmission along the optic nerve. At each synaptic stage there are also laterally connecting horizontal and amacrine cells. The optic nerve is a central tract of many axons of ganglion cells connecting primarily to the lateral geniculate body, a visual relay station in the diencephalon (the rear of the forebrain). It also projects to the superior colliculus,"
"shell or skin. An example of this can be observed in Onychophorans where the cuticula of the shell continues to the cornea. The cornea is composed of either one or two cuticular layers depending on how recently the animal has moulted. Along with the lens and two humors, the cornea is responsible for converging light and aiding the focusing of it on the back of the retina. The cornea protects the eyeball while at the same time accounting for approximately 2/3 of the eye’s total refractive power. It is likely that a key reason eyes specialize in detecting a specific,"
"Blood–retinal barrier The blood–retinal barrier, or the BRB, is part of the blood–ocular barrier that consists of cells that are joined tightly together to prevent certain substances from entering the tissue of the retina. It consists of non-fenestrated capillaries of the retinal circulation and tight-junctions between retinal epithelial cells preventing passage of large molecules from choriocapillaris into the retina. The blood retinal barrier has two components: the retinal vascular endothelium and the retinal pigment epithelium. Retinal blood vessels that are similar to cerebral blood vessels maintain the inner blood-ocular barrier. This physiological barrier comprises a single layer of non-fenestrated endothelial"