"in the frontal parts of the eye (aqueous humour) which is continuously replenished, the gel in the vitreous chamber is stagnant. Therefore, if blood, cells or other byproducts of inflammation get into the vitreous, they will remain there unless removed surgically. These are known as floaters. If the vitreous pulls away from the retina, it is known as a vitreous detachment. As the human body ages, the vitreous often liquefies and may collapse. This is more likely to occur, and occurs much earlier, in eyes that are nearsighted (myopia). It can also occur after injuries to the eye or inflammation"
"Uveitis Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is an ophthalmic emergency and requires a thorough examination by an optometrist or ophthalmologist and urgent treatment to control the inflammation. It is often associated with other ocular problems. Uveitis is classified anatomically into anterior, intermediate, posterior, and panuveitic forms—based on the part of the eye primarily affected. Prior"
"between 28% and 50%. Uveitis is estimated to be responsible for approximately 10%-20% of the blindness in the United States. Uveitis Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the outer fibrous layer composed of the sclera and cornea. The uvea consists of the middle layer of pigmented vascular structures of the eye and includes the iris, ciliary body, and choroid. Uveitis is an ophthalmic emergency and requires a thorough examination by an optometrist or ophthalmologist and urgent treatment to control the inflammation. It is often associated with other ocular problems."
"Sympathetic ophthalmia Sympathetic ophthalmia (SO) or sympathetic uveitis is a diffuse granulomatous inflammation of the uveal layer of both eyes following trauma to one eye. It can leave the affected person completely blind. Symptoms may develop from days to several years after a penetrating eye injury. It typically results from a delayed hypersensitivity reaction. Eye floaters and loss of accommodation are among the earliest symptoms. The disease may progress to severe inflammation of the uveal layer of the eye (uveitis) with pain and sensitivity of the eyes to light. The affected eye often remains relatively painless while the inflammatory disease"
"Optic papillitis Optic papillitis is a specific type of optic neuritis. Inflammation of the optic nerve head is called ""papillitis"" or ""intraocular optic neuritis""; inflammation of the orbital portion of the nerve is called ""retrobulbar optic neuritis"" or ""orbital optic neuritis"". It is often associated with substantial losses in visual fields, pain on moving the globe, and sensitivity to light pressure on the globe. It is often an early sign of multiple sclerosis. Papillitis may have the same appearance as papilledema. However, papillitis may be unilateral, whereas papilledema is almost always bilateral. Papillitis can be differentiated from papilledema by an"
"Photophthalmia Photophthalmia ( pho·toph·thal·mia (""fōt″of-thal´me-ah"") ) is ophthalmia or inflammation of the eye, especially of the cornea and conjunctiva due to exposure to intense light of short wavelength (as ultraviolet light), as in snow blindness. It involves occurrence of multiple epithelial erosions due to the effect of ultraviolet rays, especially between 311 and 290 nm. Snow blindness occurs due to reflection of ultraviolet rays from snow surface. Photoretinitis is another form that can occur due to infra-red rays (eclipse burn of retina). It can present with the following: Crooke’s glass is a prophylactic aid consisting of a spectacle lens combined"
"Endophthalmitis Endophthalmitis is an inflammation of the interior of the eye. It is a possible complication of all intraocular surgeries, particularly cataract surgery, with possible loss of vision and the eye itself. Infectious cause is the most common and various bacteria and fungi have been isolated as the cause of the endophthalmitis. Other causes include penetrating trauma, allergic reaction, and retained intraocular foreign bodies. Intravitreal injections expose patients to the risk of endophthalmitis, but with an incidence rate usually less than .05%. In cases of endophthalmitis, one usually finds a history of recent intraocular surgery or penetrating ocular trauma. In"
"Ocular immune system The ocular immune system protects the eye from infection and regulates healing processes following injuries. The interior of the eye lacks lymph vessels but is highly vascularized, and many immune cells reside in the uvea, including mostly macrophages, dendritic cells, and mast cells. These cells fight off intraocular infections, and intraocular inflammation can manifest as uveitis (including iritis) or retinitis. The cornea of the eye is immunologically a very special tissue. Its constant exposure to the exterior world means that it is vulnerable to a wide range of microorganisms while its moist mucosal surface makes the cornea"
"loss of an eye when he was six years old. Sympathetic ophthalmia Sympathetic ophthalmia (SO) or sympathetic uveitis is a diffuse granulomatous inflammation of the uveal layer of both eyes following trauma to one eye. It can leave the affected person completely blind. Symptoms may develop from days to several years after a penetrating eye injury. It typically results from a delayed hypersensitivity reaction. Eye floaters and loss of accommodation are among the earliest symptoms. The disease may progress to severe inflammation of the uveal layer of the eye (uveitis) with pain and sensitivity of the eyes to light. The"
"Graves' ophthalmopathy Graves ophthalmopathy (also known as thyroid eye disease (TED), dysthyroid/thyroid-associated orbitopathy (TAO), Graves' orbitopathy (GO)) is an autoimmune inflammatory disorder of the orbit and periorbital tissues, characterized by upper eyelid retraction, lid lag, swelling, redness (erythema), conjunctivitis, and bulging eyes (exophthalmos). It occurs most commonly in individuals with Graves' disease, and less commonly in individuals with Hashimoto's thyroiditis, or in those who are euthyroid. It is part of a systemic process with variable expression in the eyes, thyroid, and skin, caused by autoantibodies that bind to tissues in those organs. The autoantibodies target the fibroblasts in the eye"
"Ophthalmic artery The ophthalmic artery (OA) is the first branch of the internal carotid artery distal to the cavernous sinus. Branches of the OA supply all the structures in the orbit as well as some structures in the nose, face and meninges. Occlusion of the OA or its branches can produce sight-threatening conditions. The OA emerges from the internal carotid artery usually just after the latter emerges from the cavernous sinus although in some cases, the OA branches just before the internal carotid exits the cavernous sinus. The OA arises from the internal carotid along the medial side of the"
"Exophthalmos Exophthalmos (also called exophthalmus, exophthalmia, proptosis, or exorbitism) is a bulging of the eye anteriorly out of the orbit. Exophthalmos can be either bilateral (as is often seen in Graves' disease) or unilateral (as is often seen in an orbital tumor). Complete or partial dislocation from the orbit is also possible from trauma or swelling of surrounding tissue resulting from trauma. In the case of Graves' disease, the displacement of the eye is due to abnormal connective tissue deposition in the orbit and extraocular muscles which can be visualized by CT or MRI. If left untreated, exophthalmos can cause"
"Optic neuritis Optic neuritis is a demyelinating inflammation of the optic nerve. It is also known as optic papillitis (when the head of the optic nerve is involved) and retrobulbar neuritis (when the posterior part of the nerve is involved). It is most often associated with multiple sclerosis, and it may lead to complete or partial loss of vision in one or both eyes. Partial, transient vision loss (lasting less than one hour) can be an indication of early onset multiple sclerosis. Other possible diagnoses include: diabetes mellitus, low phosphorus levels, or hyperkalaemia. Major symptoms are sudden loss of vision"
"can affect many other organ systems. Inflammation of the interior portion of the eye, known as uveitis, can cause blurred vision and eye pain, especially when exposed to light (photophobia). Inflammation may also involve the white part of the eye (sclera), a condition called episcleritis. Both episcleritis and uveitis can lead to loss of vision if untreated. Crohn's disease that affects the ileum may result in an increased risk of gallstones. This is due to a decrease in bile acid resorption in the ileum and the bile gets excreted in the stool. As a result, the cholesterol/bile ratio increases in"
"Episcleritis Episcleritis is a benign, self-limiting inflammatory disease affecting part of the eye called the episclera. The episclera is a thin layer of tissue that lies between the conjunctiva and the connective tissue layer that forms the white of the eye (sclera). Episcleritis is a common condition, and is characterized by the abrupt onset of painless eye redness. There are two types of episcleritis, nodular and simple. Nodular episcleritis lesions have raised surface. Simple episcleritis lesions are flat. There are two subtypes. In diffuse simple episcleritis, inflammation is generalized. In sectoral simple episcleritis, the inflammation is restricted to one region."
"the ophthalmic artery causes ocular ischemic syndrome. As with central retinal artery occlusions, ophthalmic artery occlusions may result from systemic cardiovascular diseases; however, a cherry-red spot is typically absent and the vision is usually worse. Amaurosis fugax is a temporary loss of vision that occurs in two conditions which cause a temporary reduction in ophthalmic artery pressure: orthostatic hypotension and positive acceleration. Even complete occlusion of the ophthalmic artery may possibly leave the eye without symptoms, probably because of circulatory anastomoses Ophthalmic artery The ophthalmic artery (OA) is the first branch of the internal carotid artery distal to the cavernous"
"suggested ""Bleak House"" to have taken place in 1827. Optic neuritis Optic neuritis is a demyelinating inflammation of the optic nerve. It is also known as optic papillitis (when the head of the optic nerve is involved) and retrobulbar neuritis (when the posterior part of the nerve is involved). It is most often associated with multiple sclerosis, and it may lead to complete or partial loss of vision in one or both eyes. Partial, transient vision loss (lasting less than one hour) can be an indication of early onset multiple sclerosis. Other possible diagnoses include: diabetes mellitus, low phosphorus levels,"
"Retinitis Retinitis is inflammation of the retina in the eye, which can permanently damage the retina and lead to blindness. The retina is the part of your eye that is also known as the ""sensing tissue."" Retinitis may be caused by a number of different infectious agents. Retinitis, also called Retinitis pigmentosa, has a prevalence of one in every 2,500-7,000 people. This condition is one of the leading causes that leads to blindness in patients in the age range of 20–60 years old. Retinitis may be caused by several infectious agents, including toxoplasmosis, cytomegalovirus and candida. Cytomegalovirus retinitis is an"
"is the most exposed surface, highly vulnerable to blunt force trauma. The base, which opens in the face, has four borders. The following bones take part in their formation: The orbit holds and protects the eye. The movement of the eye is controlled by six distinct extraocular muscles, a superior, an inferior, a medial and a lateral rectus, as well as a superior and an inferior oblique. The superior ophthalmic vein is a sigmoidal vessel along the superior margin of the orbital canal that drains deoxygenated blood from surrounding musculature. The ophthalmic artery is a crucial structure in the orbit,"
"Orchitis Orchitis or orchiditis (from the Ancient Greek ὄρχις meaning ""testicle""; same root as ""orchid"") is inflammation of the testes. It can also involve swelling, heavy pains and frequent infection, particularly of the epididymis, and is more rarely known as didymitis (as in ""epididymis""). Symptoms of orchitis are similar to those of testicular torsion. These can include: Orchitis can be related to epididymitis infection that has spread to the testicles (then called ""epididymo-orchitis""), sometimes caused by the sexually transmitted diseases chlamydia and gonorrhea. It has also been reported in cases of males infected with brucellosis. Orchitis can also be seen"
"(i.e., the body's inability to distinguish between them, with resulting misdirected inflammatory reactions). See uveitis, choroiditis, iritis, iridocyclitis, anterior uveitis, sympathetic ophthalmia, and uveal melanoma. Uvea The uvea (/ˈjuːvɪə/) (Lat. ""uva"", grape), also called the ""uveal layer"", ""uveal coat"", ""uveal tract"", ""vascular tunic"" or ""vascular layer"" is the pigmented middle of the three concentric layers that make up an eye. The name is possibly a reference to its reddish-blue or almost black colour, wrinkled appearance and grape-like size and shape when stripped intact from a cadaveric eye. Its use as a technical term in anatomy and ophthalmology is relatively modern."
"Conjunctivitis Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid. It makes the eye appear pink or reddish. Pain, burning, scratchiness, or itchiness may occur. The affected eye may have increased tears or be ""stuck shut"" in the morning. Swelling of the white part of the eye may also occur. Itching is more common in cases due to allergies. Conjunctivitis can affect one or both eyes. The most common infectious causes are viral followed by bacterial. The viral infection may occur along with"
"days; usually the crusts fall off and the skin heals, but sometimes, after severe blistering, scarring and discolored skin remain. Shingles may have additional symptoms, depending on the dermatome involved. The trigeminal nerve is the most commonly involved nerve, of which the ophthalmic division is the most commonly involved branch. When the virus is reactivated in this nerve branch it is termed ""zoster ophthalmicus"". The skin of the forehead, upper eyelid and orbit of the eye may be involved. Zoster ophthalmicus occurs in approximately 10% to 25% of cases. In some people, symptoms may include conjunctivitis, keratitis, uveitis, and optic"
"to the twentieth century, uveitis was typically referred to in English as ""ophthalmia."" Most common: Intermediate uveitis normally only affects one eye. Less common is the presence of pain and photophobia. Inflammation in the back of the eye is commonly characterized by: Uveitis is usually an isolated illness, but can be associated with many other medical conditions. In anterior uveitis, no associated condition or syndrome is found in approximately one-half of cases. However, anterior uveitis is often one of the syndromes associated with HLA-B27. Presence of this type of HLA allele has a relative risk of evolving this disease by"
"Ophthalmoparesis Ophthalmoparesis or ophthalmoplegia refers to weakness (-paresis) or paralysis (-plegia) of one or more extraocular muscles which are responsible for eye movements. It is a physical finding in certain neurologic, ophthalmologic, and endocrine disease. Internal ophthalmoplegia means involvement limited to the pupillary sphincter and ciliary muscle. External ophthalmoplegia refers to involvement of only the extraocular muscles. Complete ophthalmoplegia indicates involvement of both. Ophthalmoparesis can result from disorders of various parts of the eye and nervous system: Thiamine deficiency can cause ophthalmoparesis in susceptible persons; this is part of the syndrome called Wernicke encephalopathy. The causal pathway by which this"
"eye. Graves disease may also cause axial protrusion of the eye, known as Graves' ophthalmopathy, due to buildup of extracellular matrix proteins and fibrosis in the rectus muscles. Development of Graves' ophthalmopathy may be independent of thyroid function. Orbit (anatomy) In anatomy, the orbit is the cavity or socket of the skull in which the eye and its appendages are situated. “Orbit” can refer to the bony socket, or it can also be used to imply the contents. In the adult human, the volume of the orbit is , of which the eye occupies . The orbital contents comprise the"
"is not the hidden culprit. Ophthalmic examination may reveal neovascularization (creation of new vessels in the retina), retinal vessel narrowing, retinal vessel cuffing, retinal hemorrhage, or possible vitritis (inflammation of the vitreous body) or choroiditis (inflammation of the choroid). Retinal vasculitis Retinal vasculitis is inflammation of the vascular branches of the retinal artery, caused either by primary ocular disease processes, or as a specific presentation of any systemic form of vasculitis such as Behçet's disease, sarcoidosis, multiple sclerosis, or any form of systemic nectrozing vasculitis such as temporal arteritis, polyarteritis nodosa, and granulomatosis with polyangiitis, or due to lupus erythematosus,"
"spreads through the uvea, where characteristic focal infiltrates in the choroid named Dalén-Fuchs nodules can be seen. The retina, however, usually remains uninvolved, although perivascular cuffing of the retinal vessels with inflammatory cells may occur. Swelling of the optic disc (papilledema), secondary glaucoma, vitiligo, and poliosis of the eyelashes may accompany SO. Sympathetic ophthalmia is currently thought to be an autoimmune inflammatory response toward ocular antigens, specifically a delayed hypersensitivity to melanin-containing structures from the outer segments of the photoreceptor layer of the retina. The immune system, which normally is not exposed to ocular proteins, is introduced to the contents"
"weak evidence suggesting that ivermectin could result in reduced chorioretinal lesions in patients with onchocercal eye disease. More research is needed to support this finding. Chorioretinitis Chorioretinitis is an inflammation of the choroid (thin pigmented vascular coat of the eye) and retina of the eye. It is a form of posterior uveitis. If only the choroid is inflamed, not the retina, the condition is termed choroiditis. The ophthalmologist's goal in treating these potentially blinding conditions is to eliminate the inflammation and minimize the potential risk of therapy to the patient. Symptoms may include the presence of floating black spots, blurred"
"tumor is called basal cell carcinoma. This tumor can grow around the eye but rarely spreads to other parts of the body. Other types of common eyelid cancers include squamous carcinoma, sebaceous carcinoma and malignant melanoma. The most common orbital malignancy is ""orbital lymphoma"". This tumor can be diagnosed by biopsy with histopathologic and immunohistochemical analysis. Most patients with orbital lymphoma can be offered chemotherapy or radiation therapy. Orbital dermoid cysts are benign choristomas which are typically found at the junction of sutures, most commonly at the fronto-zygomatic suture. Large deep orbital dermoid cysts can cause pressure effects on the"
"70% of all people with acute conjunctivitis present to primary care and urgent care. Conjunctivitis Conjunctivitis, also known as pink eye, is inflammation of the outermost layer of the white part of the eye and the inner surface of the eyelid. It makes the eye appear pink or reddish. Pain, burning, scratchiness, or itchiness may occur. The affected eye may have increased tears or be ""stuck shut"" in the morning. Swelling of the white part of the eye may also occur. Itching is more common in cases due to allergies. Conjunctivitis can affect one or both eyes. The most common"
"the eye, causing eye pain, redness, floaters and sensitivity to light. This is thought to be due to the association that both AS and uveitis have with the inheritance of the HLA-B27 antigen. Inflammation of the prostate occurs with increased frequency in men. Cardiovascular involvement may include inflammation of the aorta, aortic valve insufficiency or disturbances of the heart's electrical conduction system. Lung involvement is characterized by progressive fibrosis of the upper portion of the lung. Ankylosing spondylitis (AS) is a systemic rheumatic disease, meaning it affects the entire body. Approximately 90% of people with AS express the HLA-B27 genotype,"
"decades of life. Scleritis Scleritis is a serious inflammatory disease that affects the white outer coating of the eye, known as the sclera. The disease is often contracted through association with other diseases of the body, such as granulomatosis with polyangiitis or rheumatoid arthritis. There are three types of scleritis: diffuse scleritis (the most common), nodular scleritis, and necrotizing scleritis (the most severe). Scleritis may be the first symptom of onset of connective tissue disease. Episcleritis is inflammation of the episclera, a less serious condition that seldom develops into scleritis. Symptoms of scleritis include: The pain of episcleritis is less"