"to differentiate into various tissues, which may be useful for future human application. Some researchers have found that amniotic fluid is also a plentiful source of non-embryonic stem cells. These cells have demonstrated the ability to differentiate into a number of different cell-types, including brain, liver and bone. It is possible to conserve the stem cells extracted from amniotic fluid in private stem cells banks. Some private companies offer this service for a fee. Amniotic fluid The amniotic fluid is the protective liquid contained by the amniotic sac of a gravid amniote. This fluid serves as a cushion for the"
"Amniotic fluid The amniotic fluid is the protective liquid contained by the amniotic sac of a gravid amniote. This fluid serves as a cushion for the growing fetus, but also serves to facilitate the exchange of nutrients, water, and biochemical products between mother and fetus. For humans, the amniotic fluid is commonly called water or waters (Latin liquor amnii). Amniotic fluid is present from the formation of the gestational sac. Amniotic fluid is in the amniotic sac. It is generated from maternal plasma, and passes through the fetal membranes by osmotic and hydrostatic forces. When fetal kidneys begin to function"
"contributes to the formation of meconium. Amniotic fluid protects the developing baby by cushioning against blows to the mother's abdomen, allowing for easier fetal movement and promoting muscular/skeletal development. Amniotic fluid swallowed by the fetus helps in the formation of the gastrointestinal tract. Contrary to popular belief, amniotic fluid has not been conclusively shown to be inhaled and exhaled by the fetus. In fact, studies from the 1970s show that in a healthy fetus, there is no inward flow of amniotic fluid into the airway. Instead, lung development occurs as a result of the production of fetal lung fluid which"
"fluid increases with the growth of fetus. From the 10th to the 20th week it increases from 25ml to 400ml approximately. Approximately in the 10th-11th week the breathing and swallowing of the fetus slightly decrease the amount of fluid, but neither urination nor swallowing contributes significantly to fluid quantity changes, until the 25th week, when keratinization of skin is complete. Then the relationship between fluid and fetal growth stops. It reaches a plateau of 800ml by the 28-week gestational age. The amount of fluid declines to roughly 400 ml at 42 weeks. There is about 1L of amniotic fluid at"
"Amniotic sac The amniotic sac, commonly called the bag of waters, sometimes the membranes, is the sac in which the fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth. The inner of these fetal membranes, the amnion, encloses the amniotic cavity, containing the amniotic fluid and the fetus. The outer membrane, the chorion, contains the amnion and is part of the placenta. On the outer side, the amniotic sac is connected to the yolk sac, the allantois and, via the umbilical cord, to"
"in about week 16, fetal urine also contributes to the fluid. In earlier times, it was believed that the amniotic fluid was composed entirely of fetal urine. The fluid is absorbed through the fetal tissue and skin. After the 15th-25th week of pregnancy when the keratinization of an embryo's skin occurs, the fluid is primarily absorbed by the fetal gut. At first, amniotic fluid is mainly water with electrolytes, but by about the 12-14th week the liquid also contains proteins, carbohydrates, lipids and phospholipids, and urea, all of which aid in the growth of the fetus. The volume of amniotic"
"week amniotic fluid (also called ""liquor amnii"") begins to accumulate within it. This fluid increases in quantity and causes the amnion to expand and ultimately to adhere to the inner surface of the chorion, so that the extra-embryonic part of the coelom is obliterated. The amniotic fluid increases in quantity up to the sixth or seventh month of pregnancy, after which it diminishes somewhat; at the end of pregnancy it amounts to about 1 liter. The amniotic fluid allows the free movements of the fetus during the later stages of pregnancy, and also protects it by diminishing the risk of"
"system, form relatively early during embryonic development, but continue to grow and develop in complexity in the growing fetus. A functional circulatory system is a biological necessity, since mammalian tissues can not grow more than a few cell layers thick without an active blood supply. The prenatal circulation of blood is different than the postnatal circulation, mainly because the lungs are not in use. The fetus obtains oxygen and nutrients from the mother through the placenta and the umbilical cord. Blood from the placenta is carried to the fetus by the umbilical vein. About half of this enters the fetal"
"artificial rupture of membranes (AROM), also known as an amniotomy, may be clinically performed using an amnihook or amnicot in order to induce or to accelerate labour. Amniotic sac The amniotic sac, commonly called the bag of waters, sometimes the membranes, is the sac in which the fetus develops in amniotes. It is a thin but tough transparent pair of membranes that hold a developing embryo (and later fetus) until shortly before birth. The inner of these fetal membranes, the amnion, encloses the amniotic cavity, containing the amniotic fluid and the fetus. The outer membrane, the chorion, contains the amnion"
"fetus. It forms into the skin, nervous system, enamel of the teeth, lining of the intestine, mammary and sweat glands, hoofs, and hair. The mesoderm forms the major organ components that help keep the fetus alive. It forms the muscles and connective tissues of the body, blood vessels and cells, the skeleton, kidneys, adrenal glands, heart, and the reproductive organs. By day 20, most of the major organs are visible, and the last half of gestation focuses greatly on increasing the size of the fetuses. The development of the lymphatic system and the formation of blood circulation occur at different"
"few days after delivery, the mother produces colostrum. This is a thin yellowish fluid that is the same fluid that sometimes leaks from the breasts during pregnancy. It is rich in protein and antibodies that provide passive immunity to the baby (the baby's immune system is not fully developed at birth). Colostrum also helps the newborn's digestive system to grow and function properly. Colostrum will gradually change to become mature milk. In the first 3–4 days it will appear thin and watery and will taste very sweet; later, the milk will be thicker and creamier. Human milk quenches the baby's"
"Development of the human body Human development is the process of growth to maturity. The process begins with fertilisation, where an egg released from the ovary of a female is penetrated by a sperm cell from a male. The egg then lodges in the uterus, where an embryo and later fetus develop until birth. Further growth and development continues after birth, and includes both physical and psychological development, influenced by genetic, hormonal, environmental and other factors. This continues throughout life, through childhood, and adolescence into adulthood. Development before birth, or prenatal development () is the process in which an embryo"
"baby is enclosed in a fluid-filled membrane called the amniotic sac. Shortly before, at the beginning of, or during labor the sac ruptures. Once the sac ruptures, termed ""the water breaks"", the baby is at risk for infection and the mother's medical team will assess the need to induce labor if it has not started within the time they believe to be safe for the infant. Many women are known to experience what has been termed the ""nesting instinct"". Women report a spurt of energy shortly before going into labour. Folklore has long held that most babies are born in"
"than postmature birth, which occurs in 3% to 12% of pregnancies. The heart and blood vessels of the circulatory system, form relatively early during embryonic development, but continue to grow and develop in complexity in the growing fetus. A functional circulatory system is a biological necessity, since mammalian tissues can not grow more than a few cell layers thick without an active blood supply. The prenatal circulation of blood is different than the postnatal circulation, mainly because the lungs are not in use. The fetus obtains oxygen and nutrients from the mother through the placenta and the umbilical cord. Blood"
"interstitial fluid back towards the heart for return to the cardiovascular system, by emptying into the lymphatic ducts. Its other main function is in the adaptive immune system. The development of the circulatory system starts with vasculogenesis in the embryo. The human arterial and venous systems develop from different areas in the embryo. The arterial system develops mainly from the aortic arches, six pairs of arches which develop on the upper part of the embryo. The venous system arises from three bilateral veins during weeks 4 – 8 of embryogenesis. Fetal circulation begins within the 8th week of development. Fetal"
"increases by about 12 kg (26 lb). The European Food Safety Authority recommends an increase of 300 mL per day compared to the normal intake for non-pregnant women, taking the total adequate water intake (from food and fluids) to 2,300 mL, or approximately 1,850 mL/ day from fluids alone A mother's nutritional intake during pregnancy is believed to influence and possibly offer protective effects against the development of allergenic diseases and asthma in children. Maternal intake of vitamin D, vitamin E, and zinc have all been associated with a lower likelihood of wheezing in childhood, suggesting a protective effect. Additionally,"
"hemoglobin, called fetal hemoglobin (HbF, αγ), is found in the developing fetus, and binds oxygen with greater affinity than adult hemoglobin. This means that the oxygen binding curve for fetal hemoglobin is left-shifted (i.e., a higher percentage of hemoglobin has oxygen bound to it at lower oxygen tension), in comparison to that of adult hemoglobin. As a result, fetal blood in the placenta is able to take oxygen from maternal blood. Hemoglobin also carries nitric oxide (NO) in the globin part of the molecule. This improves oxygen delivery in the periphery and contributes to the control of respiration. NO binds"
"Amnion The amnion is a membrane that closely covers the embryo when first formed. It fills with the amniotic fluid which causes the amnion to expand and become the amniotic sac which serves to provide a protective environment for the developing embryo or fetus. The amnion, along with the chorion, the yolk sac and the allantois form a protective sac around the embryo. In birds, reptiles and monotremes, the protective sac is enclosed in a shell. In marsupials and placental mammals, it is enclosed in a uterus. The term amnion is from Ancient Greek ἀμνίον 'little lamb', diminutive of ἀμνός"
"Prenatal development Prenatal development () is the process in which an embryo and later fetus develops during gestation. Prenatal development starts with fertilization, the first stage in embryogenesis which continues in fetal development until birth. In human pregnancy, prenatal development, also known as antenatal development, is the development of the embryo following fertilization, and continued as fetal development. By the end of the tenth week of gestational age the embryo has acquired its basic form and is referred to as a fetus. The next period is that of fetal development where many organs become fully developed. This fetal period is"
"The treatment depends on the cause. Severely anemic fetuses, including those with Rh disease and alpha thalassemia major, can be treated with blood transfusions while still in the womb. This treatment increases the chance that the fetus will survive until birth. Hydrops fetalis Hydrops fetalis is a condition in the fetus characterized by an accumulation of fluid, or edema, in at least two fetal compartments. By comparison, hydrops allantois or hydrops amnion is an accumulation of excessive fluid in the allantoic or amniotic space, respectively. Locations can include: The edema is usually seen in the fetal subcutaneous tissue, sometimes leading"
"amniotic fluid. If used for prenatal genetic diagnosis, fetal cells are separated from the extracted sample. The cells are grown in a culture medium, then fixed and stained. Under a microscope the chromosomes are examined for abnormalities. The most common abnormalities detected are Down syndrome (trisomy 21), Edwards syndrome (trisomy 18), and Turner syndrome (monosomy X). In regard to the fetus, the puncture seals and the amniotic sac replenishes the liquid over the next 24–48 hours. Amniotic fluid can be a rich source of multipotent mesenchymal, hematopoietic, neural, epithelial, and endothelial stem cells. A potential benefit of using amniotic stem"
"death rates, impaired lung and immune system development. Prenatal development Prenatal development () is the process in which an embryo and later fetus develops during gestation. Prenatal development starts with fertilization, the first stage in embryogenesis which continues in fetal development until birth. In human pregnancy, prenatal development, also known as antenatal development, is the development of the embryo following fertilization, and continued as fetal development. By the end of the tenth week of gestational age the embryo has acquired its basic form and is referred to as a fetus. The next period is that of fetal development where many"
"the placenta. There is relatively high pressure as the maternal blood fills intervillous space through these spiral arteries which bathe the fetal villi in blood, allowing an exchange of gases to take place. In humans and other hemochorial placentals, the maternal blood comes into direct contact with the fetal chorion, though no fluid is exchanged. As the pressure decreases between pulses, the deoxygenated blood flows back through the endometrial veins. Maternal blood flow is approximately 600–700 ml/min at term. This begins at day 5 - day 12 Deoxygenated fetal blood passes through umbilical arteries to the placenta. At the junction"
"injury from without. It contains less than two percent solids, consisting of urea and other extractives, inorganic salts, a small amount of protein, and frequently a trace of sugar. That some of the liquor amnii is swallowed by the fetus is proved by the fact that epidermal debris and hairs have been found among the contents of the fetal alimentary canal. Extra-amniotic pregnancy is a rare condition that result from a rupture of the amnion, leading to development of the fetus within the extraembryonic coelom. In reptiles, birds, and many mammals the amnion is developed in the following manner: At"
"adult's is formed within one to two years of birth. The traditional view of the gastrointestinal tract of a normal fetus is that it is sterile, although this view has been challenged in the past few years. Multiple lines of evidence have begun to emerge that suggest there may be bacteria in the intrauterine environment. In humans, research has shown that microbial colonization may occur in the fetus with one study showing ""Lactobacillus"" and ""Bifidobacterium"" species were present in placental biopsies. Several rodent studies have demonstrated the presence of bacteria in the amniotic fluid and placenta, as well as in"
"into free-living larvae that complete their development in water and later transform into either aquatic or terrestrial adults. In many species of frog and in most lungless salamanders (Plethodontidae), direct development takes place, the larvae growing within the eggs and emerging as miniature adults. Many caecilians and some other amphibians lay their eggs on land, and the newly hatched larvae wriggle or are transported to water bodies. Some caecilians, the alpine salamander (""Salamandra atra"") and some of the African live-bearing toads (""Nectophrynoides spp."") are viviparous. Their larvae feed on glandular secretions and develop within the female's oviduct, often for long"
"Hydrops fetalis Hydrops fetalis is a condition in the fetus characterized by an accumulation of fluid, or edema, in at least two fetal compartments. By comparison, hydrops allantois or hydrops amnion is an accumulation of excessive fluid in the allantoic or amniotic space, respectively. Locations can include: The edema is usually seen in the fetal subcutaneous tissue, sometimes leading to spontaneous abortion. It is a prenatal form of heart failure, in which the heart is unable to satisfy demand (in most cases abnormally high) for blood flow. Hydrops fetalis usually stems from fetal anemia, when the heart needs to pump"
"the placenta, where carbon dioxide and other waste products from the fetus are taken up and enter the maternal circulation. Some of the blood entering the right atrium does not pass directly to the left atrium through the ""foramen ovale"", but enters the right ventricle and is pumped into the pulmonary artery. In the fetus, there is a special connection between the pulmonary artery and the aorta, called the ""ductus arteriosus"", which directs most of this blood away from the lungs (which are not being used for respiration at this point as the fetus is suspended in amniotic fluid). The"
"fetus accumulates copper rapidly in its liver during the third trimester of pregnancy. At birth, a healthy infant has four times the concentration of copper than a full-grown adult. Human milk is relatively low in copper, and the neonate's liver stores falls rapidly after birth, supplying copper to the fast-growing body during the breast feeding period. These supplies are necessary to carry out such metabolic functions as cellular respiration, melanin pigment and connective tissue synthesis, iron metabolism, free radical defense, gene expression, and the normal functioning of the heart and immune systems in infants. Infants have special biochemical mechanisms for"
"fluid are removed. Analysis of amniotic fluid can reveal many aspects of the baby's genetic health as well as the age and viability of the fetus. This is because the fluid contains metabolic wastes and compounds used in assessing fetal age and lung maturity, but amniotic fluid also contains fetal cells, which can be examined for genetic defects. Amniotic fluid normally has a pH of 7.0 to 7.5. Because pH in the upper vagina is normally acidic (pH 3.8-4.5), a vaginal pH test showing a pH of more than 4.5 strengthens a suspicion of rupture of membranes in case of"
"expands the lungs. It also prevents the fetus from mechanical jerks and shocks. Amniotic fluid is removed from the mother by an amniocentesis procedure, where a long needle is inserted through the abdomen into the amniotic sac, using ultrasound guidance such that the fetus is not harmed. Amniocentesis is an abnormal procedure, and is only performed if there is a suspicion of health defects in the fetus, or if an early delivery of the fetus may be necessary, since there can be complications from the procedure. If warranted, fluid is collected between 16–42 weeks of fetal development, and 20-30ml of"
"by the kidneys via urination. Oligohydramnios occurs if the volume of amniotic fluid is less than normal for the corresponding period of gestation. The fetal urine is critical to the proper development of the lungs by aiding in the expansion of the airways - alveoli, by means of hydrodynamic pressure and by also supplying proline which is a critical amino acid for lung development. Alveoli are the small sacs in the lungs that exchange oxygen with the blood. If the alveoli, and thereby the lungs, are underdeveloped at the time of birth the infant will not be able to breathe"
"such as rodents and primates, the vascular resistance in the placenta was low, leading scientists to the conclusion that the greatest resistance to maternal blood flow is found elsewhere in the maternal vascular system. The high vascular resistance outside of the placenta leads to higher maternal blood pressure throughout the body. The fetal cells that implant into the uterine wall are known as the trophoblast. The hemochorial placenta bathes the fetal trophoblast in maternal blood by forming lacunae, or lakes, of the mother's blood that surround fetal tissue. The lacunae are filled by the spiral arteries, which means that the"