"Pacific consumed in the USA. The concerns being addressed in the UK are different from those in the USA: they are preventative to ensure that tuna sold does not become unsafe for dolphins, rather than rectifying an existing environmental problem. The dolphin-safe movement in the U.S. was led by environmental and consumer groups in response to the use of total encirclement netting. With this method, fishermen surrounded dolphin pods along with the tuna they were catching and the dolphins were given no chance to escape before the nets were lifted. This resulted in large numbers of dolphins being killed, imperiling"
"by-catch contained no dolphins. It does not specify that the by-catch contained no other species, nor does it imply anything about the environmental impact of the hunt itself. In May 2012, the World Trade Organization ruled that the dolphin safe label, as used in the U.S., focuses too narrowly on fishing methods, and too narrowly on the Eastern Tropical Pacific. The U.S. label does not address dolphin mortalities in other parts of the world. The US subsequently expanded reporting and verification procedures to all oceans of the world, while maintaining the strong standards for the Dolphin Safe label, to come"
"countries such as Austria, Bulgaria, Finland, France, Portugal, and Russia. It is also available in Japan (as Toledomin) and Mexico (as Dalcipran). Cypress Bioscience bought the exclusive rights for approval and marketing of the drug for any purpose in the United States and Canada in 2003 from the manufacturer Laboratoires Pierre Fabre. In January 2009 the U.S. Food and Drug Administration (FDA) approved milnacipran (under the brand name Savella) only for the treatment of fibromyalgia, making it the third medication approved for this purpose in the United States. In July and November 2009, the European Medicines Agency refused marketing authorization"
"over 40 years with no safety issues. One company that markets diosmin supplements, Nutratech, has responded that diosmin can reasonably be expected to be safe on the basis of clinical trials, and has a long history of use in Europe. In the U.S., dietary supplements are regulated under Dietary Supplement Health and Education Act of 1994, which does not require proof of efficacy so long as no specific health claims are made. The enhanced version of diosmin, Vasculera, is sold as a medical food product. Under FDA regulation, medical food products must obtain GRAS (generally recognized as safe) status and"
"Welfare, forerunner to the Department of Health and Human Services, nalbuphine was removed from schedule II of the CSA in 1976. Presently, nalbuphine is not a controlled substance under the CSA. Nalbuphine HCL is currently available only as an injectable in the US and the European Union. Nubain, the Astra USA brand name for injectable nalbuphine HCL, was discontinued from being marketed in 2008 in the United States for commercial reasons (Federal Register 2008); however, other commercial suppliers now provide generic injection formulation nalbuphine for the market. Nalbuphine is marketed primarily under the brand names Nubain, Nalpain, and Nalbuphin. It"
"that addresses all the different toxins that children are exposed to in traditional household products. In the U.S., the F.D.A has banned fewer than a dozen harmful chemicals, while in Europe more than 1,300 chemicals are deemed unsafe for household products. With this research, Alba and Gavigan decided to create a company that avoids putting those 1,300 chemicals in its products. While building her company, Alba has lobbied the United States Congress to make testing of consumer products in the marketplace for chemical inputs more stringent. The company has a strong charitable mission that has been likened to Toms Shoes,"
"levels. Some findings even suggest that dextromethorphan can actually ""counter"" the dopamine-increasing effect caused by morphine. Due to these conflicting results, the actual effect of dextromethorphan on dopamine levels remains undetermined. Antitussive preparations containing dextromethorphan are legal to purchase from pharmacies in most countries, with some exceptions being UAE, France, Sweden, Estonia and Latvia. In Russia, dextromethorphan (commonly sold under the brand names Tussin+ and Glycodin) is a Schedule III controlled substance and is placed in the same list as benzodiazepines and the majority of barbiturates. No legal distinction currently exists in the United States between medical and recreational use,"
"GATT. For these reasons, the panel did not rule in favor of the United States. The International Dolphin Conservation Program Act (IDCPA) which was passed August 15, 1997, amended the Dolphin Consumer Information Act of 1990, by changing both the labeling standards and meaning of ""dolphin safe."" It codified the Declaration of Panama, an international agreement signed by Belize, Colombia, Costa Rica, Ecuador, France, Honduras, Mexico, Panama, Spain, the United States, Vanuatu, and Venezuela. The Declaration established the International Dolphin Conservation Program for purposes of reducing dolphin mortality, while at the same time creating a viable yellowfin tuna harvesting program."
"safely and is non-toxic, according to EU chemicals legislation. Mepron (rumen-protected methionine) Mepron is the brand name for a time-released, rumen-protected DL-Methionine capsule for dairy cattle. It is a registered trademark of Evonik Industries. The product is a 1.8 mm x 3 mm, nearly-white cylindrical granule. The granules are free-flowing, and nearly insoluble in water. The product is nearly dust-free, and has a high level of durability. It is coated in ethylcellulose, a rugged and durable fiber. Mepron is also heat- and pH-tolerant, and has a long shelf life. Dairy-herd milk production may be limited by the amino acid methionine;"
"review by the Federal Drug Administration (FDA). Dapoxetine has been marketed and approved in more than 50 countries. Dapoxetine has been approved in Italy, Spain, Mexico, South Korea, and New Zealand in 2009 and 2010; marketed in Sweden, Austria, Germany, Finland, Spain, Portugal, and Italy. It has also been approved in France, Russia, Malaysia, Philippines, Argentina, and Uruguay. Dapoxetine is sold under a variety of brand names including Dumax, Duratia, Joybox, Kutub, Lejam, Longride Pentenal-30, Priligy, Sustinex, Ever Long, Joytab, Westoxetin and Primaxetin. Dapoxetine Dapoxetine, marketed as Priligy and Westoxetin, among and other brands, is the first compound developed specially"
"available in 58 countries, including Canada, but the uses or ""indications"" of domperidone vary between nations. In Italy it is used in the treatment of gastroesophageal reflux disease and in Canada, the drug is indicated in upper gastrointestinal motility disorders and to prevent gastrointestinal symptoms associated with the use of dopamine agonist antiparkinsonian agents. In the United Kingdom, domperidone is only indicated for the treatment of nausea and vomiting and the treatment duration is usually limited to 1 week. In the United States, domperidone is not currently a legally marketed human drug and it is not approved for sale in"
"similar to the ""dolphin safe"" labels used for tuna. The amendment was approved in the House of Representatives vote of 291–115. The bill appeared to have similar support in the Senate. The international cocoa industry strongly opposed it and the Chocolate Manufacturers Association hired former senators George Mitchell and Bob Dole to lobby against it. The cocoa industry faced potential consumer boycotts and harmful legislation if the bill were to pass. Mitchell and Dole encouraged the industry to make a deal, and before the bill went to a vote in the Senate, the cocoa industry agreed to address the problem"
"academics argue that sentence 2 is read in context of sentence 1, and should therefore be given narrower scope. The Panel in Tuna-Dolphin GATT Case (I and II) did not clarify this issue, but held in that case that the dolphin-safe labeling was a technical regulation by reason of the second sentence. Accordingly, it may be assumed that labeling of NPRP-PPM products now fall under the scope of technical regulations. Members must ensure that technical regulations and standards do not accord treatments less favorable to imported products compared to the ones granted to like products of national origin or creating"
"Administration (FDA) moved it from the “generally recognized as safe” classification into the “untested” classification to effectively halt its distribution in the United States on over fears of potential mercury poisoning. Sales were halted in Brazil in 2001, Germany in 2003, and in France in 2006. It is readily available in most other countries. Within the United States, products such as Humco Mercuroclear play on the brand recognition history of Mercurochrome, but substitute other ingredients with similar properties (Mercuroclear: ""Aqueous solution of benzalkonium chloride and lidocaine hydrochloride""). Merbromin Merbromin (marketed as Mercurochrome, Merbromine, Mercurocol, Sodium mercurescein, Asceptichrome, Supercrome, Brocasept and"
"available only to licensed professionals and specially certified growers who are trained in its proper and safe use. In the US, occupational exposure limits have been set at 0.1 ppm over an eight-hour time-weighted average. In 2008 the US EPA re-approved chloropicrin as safe for use in agricultural settings, stating that treatments ""can provide benefits to both food consumers and growers. For consumers, it means more fresh fruits and vegetables can be cheaply produced domestically year-round because several severe pest problems can be efficiently controlled."" To ensure chloropicrin is used safely, the EPA requires a strict set of protections for"
"products in compliance with the GMP regulations for pharmaceuticals, resulting in products without pharmaceutical requirements. While it is a prescription or over-the-counter drug in 22 countries, chondroitin is regulated in the U.S. as a dietary supplement by the Food and Drug Administration. In Europe, chondroitin sulfate formulations are approved as drugs with evidenced efficacy and safety demonstrated by clinical trials in people with osteoarthritis. Adebowale et al. reported in 2000 that of 32 chondroitin supplements they analysed, only 5 were labeled correctly, and more than half contained less than 40% of the labeled amount. With the introduction of GMP regulations"
"not been approved for any use in the US, Canada, or Japan. A Teva recalled batches of dopexamine in the UK in 2014 due to quality control issues by the manufacturer, Cephalon. Use in [[sepsis]] has been explored in clinical trials, but use of an inotropic agent like [[dobutamine]] or dopexamine did not reduce mortality compared with [[norepinephrine]] or [[epinephrine]]. Use of dopexamine may be harmful in sepsis [[Category:Beta-adrenergic agonists]] [[Category:Cardiac stimulants]] [[Category:Catecholamines]] [[Category:Dopamine agonists]] [[Category:Norepinephrine reuptake inhibitors]] Dopexamine Dopexamine is a synthetic analogue of dopamine that is administered intravenously in hospitals to reduce exacerbations of heart failure and to"
"produced by Orchid in January 2010; Cephalon sued to prevent sale, but lost the patent trial in November. Modafinil is classified as a Schedule IV controlled substance under United States federal law; it is illegal to import by anyone other than a DEA-registered importer without a prescription. However, one may legally bring modafinil into the United States in person from a foreign country, provided that he or she has a prescription for it, and the drug is properly declared at the border crossing. U.S. residents are limited to 50 dosage units (e.g., pills). Under the US Pure Food and Drug"
"in 11 other countries, including Argentina, Columbia, Dominica, Honduras, Nicaragua, Pakistan, South Africa, Turkey, and Venezuela. In the Stockholm Convention on POPs, which came into effect on 17 May 2004, twelve POPs were listed to be eliminated or their production and use restricted. The OCPs or pesticide-POPs identified on this list have been termed the ""dirty dozen"" and include aldrin, chlordane, DDT, dieldrin, endrin, heptachlor, hexachlorobenzene, mirex, and toxaphene. The EPA has determined that lifetime exposure to 0.01 milligrams per liter of toxaphene in the drinking water is not expected to cause any adverse noncancer effects if the only source"
"are still healthy. He was countered by Sydney Postharvest Laboratory director Dr Stephen Morris in that Vitamin C and antioxidant levels may still decline, a concern also shared by others in the industry. SmartFresh is perceived by Susan Kegley, a senior scientist at the San Francisco-based Pesticide Action Network North America, as being “likely to be very low-risk to consumers”. Other scientists see 1-MCP as ""most likely harmless to humans"". As of 2009, this product is allowed in more than 26 countries: Argentina, Australia, Brazil, Canada, Chile, China, Costa Rica, Guatemala, Israel, Mexico, New Zealand, Nicaragua, South Africa, Switzerland, Turkey,"
"Japan and Western Europe. Recombinant activated protein C (drotrecogin alpha) in a 2011 Cochrane review was found not to decrease mortality and to increase bleeding, and thus, was not recommended for use. Drotrecogin alfa (Xigris), was withdrawn from the market in October 2011. Sepsis has a worldwide incidence of more than 20 million cases a year, with mortality due to septic shock reaching up to 50 percent even in industrialized countries. According to the U.S. Centers for Disease Control, septic shock is the thirteenth leading cause of death in the United States and the most frequent cause of deaths in"
"Medicines, the most effective and safe medicines needed in a health system. In the United States it can be obtained from the Center for Disease Control. It is not available in many countries including many in Europe as of 2008. It is a solution of concentrated proteins, chiefly globulins, containing antibodies obtained from the blood of horses that have been immunized against diphtheria toxin. Diphtheria antitoxin Diphtheria antitoxin (DAT) is a medication made up of antibodies used in the treatment of diphtheria. It is no longer recommended for prevention of diphtheria. It is given by injection into a vein or"
"in Tuna-Dolphin GATT Case (I and II) held that the US labeling measures for dolphin-safe tuna was a technical regulation. The requirements were not compulsory for the sale of tuna in the US, however the requirements were compulsory for dolphin-safe certification. The Appellate Body stated that because the US provided no other methods of obtaining the dolphin-safe label, the requirement was binding, and therefore de jure mandatory. It appears from this decision that measures that attempt to obtain a monopoly over a specific label will be deemed technical regulations, but the test is ultimately on a case-by-case basis. This decision"
"the Philippines and South Africa to name a few. USA<br> Headquartered in Baltimore, Maryland, Lupin Pharmaceuticals Inc. (LPI) ], the company's US subsidiary is a $891 million enterprise. It has a presence in the branded and generics markets of the US. In the branded business, Lupin operates in the CVS and Pediatric segments. The company is the market leader in 28 products out of the 77 products marketed in the US generics market, of which it is amongst the Top 3 by market share in 57 of these products (IMS Health, December 2014): Suprax (Cefixime), a paediatric antibiotic, is Lupin’s"
"of a hydrochloride salt, to be sold under the name Aplenzin by Sanofi-Aventis. In 2012, the U.S. Justice Department announced that GlaxoSmithKline had agreed to plead guilty and pay a $3-billion fine, in part for promoting the unapproved use of Wellbutrin for weight loss and sexual dysfunction. Bupropion is the International Nonproprietary Name (INN) and British Approved Name (BAN) while bupropion hydrochloride is the United States Adopted Name (USAN). Amfebutamone was the former INN. According to the US government classification of psychiatric medications, bupropion is ""non-abusable"". However, in animal studies, squirrel monkeys and rats could be induced to self-administer bupropion"
"Dofetilide Dofetilide is a class III antiarrhythmic agent. It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 µg of dofetilide. It is not available in Europe or Australia. Due to the pro-arrhythmic potential of dofetilide, it is only available by prescription from physicians who have undergone specific training in the risks of treatment with dofetilide. In addition, it is only available by mail order or through specially trained local pharmacies. Dofetilide is used for the maintenance of sinus rhythm in individuals prone to the occurrence"
"EPA Safer Choice The U.S. Environmental Protection Agency’s (EPA’s) Safer Choice label, previously known as the Design for the Environment (DfE) label, helps consumers and commercial buyers identify and select products with safer chemical ingredients, without sacrificing quality or performance. When a product has the Safer Choice label, it means that every intentionally-added ingredient in the product has been evaluated by EPA scientists. Only the safest possible functional ingredients are allowed in products with the Safer Choice label. Safer Choice is a voluntary partnership program that is grounded in more than 40 years of EPA experience in evaluating the human"
"convinced most farmers to buy only d-CON and not a cheaper warfarin competitor, according to reports by retailers who stocked multiple brands. D-CON d-CON is a brand of rodent control products owned and distributed in the United States by the UK-based consumer goods company Reckitt Benckiser. The d-CON product line includes traps and baits for use around the home for trapping and killing rats and mice. As of 2015, bait products use first-generation vitamin K anticoagulants as poison. In 1950, the Wisconsin Alumni Research Foundation patented warfarin, a new chemical compound which had been in development since the 1930s. Chicago"
"country to country but most countries have some sort of formal legislation that either restrict or prohibit certain ingredients or products. There are two main sources for cosmetics safety: the EU Cosmetics Directive 76/768/EEC and the Canadian Cosmetic Ingredient Hotlist. Regulation in the United States by the FDA is particularly weak. A new version of the EU's Cosmetics Directive was adopted by the European Parliament, 24 March 2009. It includes new rules concerning the use of nanoparticles in cosmetics and includes stricter rules on animal testing of cosmetics. In the European Union, all cosmetic products must be notified through the"
"designed in Italy with most of them being printed, stitched, and assembled in China; this has been criticised by Moleskine customers. Since 2008, some components have been manufactured in Volant, Cahiers and Folio hard covers in Turkey, watercolour paper in France, and some components in Vietnam. The paper used in Moleskine products is Forest Stewardship Council certified and acid-free. Since August 2010, all Moleskine products, offered to retailers in California and throughout the world, comply with the Safe Drinking Water and Toxic Enforcement Act of 1986. After concerns in 2008 about PVC traces in some notebooks, all items are now"
"originated in England, where a patent was granted to Richard Stoughton's elixir in 1712. There were no federal regulations in the United States concerning safety and effectiveness of drugs until the 1906 Food and Drugs Act. Thus, the widespread marketing and availability of dubiously advertised patent medicines without known properties or origin persisted in the US for a much greater number of years than in Europe. In 18th-century Europe, especially in the UK, viper oil had been commonly recommended for many afflictions, including the ones for which oil from the rattlesnake (pit viper,) a type of viper native to America,"
"USA drotrecogin was FDA approved for the reduction of mortality in adult patients with severe sepsis (sepsis associated with acute organ dysfunction) who have a high risk of death (as determined by APACHE II scores of 25 or greater). Evidence however is not sufficiently strong for its use to become standard of care. Because of the risk of severe bleeding, associated with the use of Xigris, the following guidelines have been additionally proposed, but are not FDA requirements: On October 25, 2011, Eli Lilly and Company announced a worldwide voluntary market withdrawal of Xigris [drotrecogin alfa (activated)]. In a recent"
"origin"" and it is required to submit by the country of origin. Since Mexico did not want to comply with the new standards of modifying their fishing techniques, no products were accepted from origin of Mexico into the United States. DPCIA, or Dolphin Protection Consumer Information Act was an amendment to the Marine Mammal Protection Act (MMPA) of 1972 which would support the International Dolphin Conservation Program and management of tuna in the Eastern Tropical Pacific Ocean. Findings by Congress have shown that nations fishing for tuna in the ETP have achieved significant reductions in dolphin mortality by participating countries."