"attractive a young woman is. Human skin color Human skin color ranges in variety from the darkest brown to the lightest hues. An individual's skin pigmentation is the result of genetics, being the product of both of the individual's biological parents' genetic makeup, and exposure to sun. In evolution, skin pigmentation in human beings evolved by a process of natural selection primarily to regulate the amount of ultraviolet radiation penetrating the skin, controlling its biochemical effects. The actual skin color of different humans is affected by many substances, although the single most important substance is the pigment melanin. Melanin is"
"design. Some of the most potent competitive reversible tyrosinase inhibitors are synthetic compounds with a potency hundreds of times that of kojic acid. Melanin is the main substance responsible for the color of the skin. Melanin is class of dark polymers generated by the body through the process of melanogenesis. Among the melanin pigmenting the skin and hair, two types can be distinguished based on its chemical composition and biological route of synthesis: the black/brown eumelanin and the red/yellow pheomelanin. The variation of skin color among individuals is mostly because of variation of the content of melanin in the skin."
"in the core of each hair. Melanin is also responsible for the color of the skin and of the eyes. There are only two types of pigment: dark (eumelanin) or light (phaeomelanin). Combined in various combinations, these pigments create all natural hair colors. Melanin itself is the product of a specialized cell, the melanocyte, which is found in each hair follicle, from which the hair grows. As hair grows, the melanocyte injects melanin into the hair cells, which contain the protein keratin and which makes up our hair, skin, and nails. As long as the melanocytes continue injecting melanin into"
"which is located everywhere in the cell such as in nucleus, mitochondria, endoplasmic reticulum, Golgi body, and free in cytoplasmic matrix. Pigments: The most common pigment in the body, besides hemoglobin of red blood cells is melanin, manufactured by melanocytes of the skin and hair, pigments cells of the retina and specialized nerve cells in the substantia nigra of the brain. These pigments have protective functions in skin and aid in the sense of sight in the retina but their functions in neurons is not understood completely. Furthermore, cardiac tissue and central nervous system neurons shows yellow to brown pigment"
"concentrated melanin, i.e. darker skin tone. However; the relationship between skin pigmentation and photoprotection is still being investigated. In humans, melanin is the primary determinant of skin color. It is also found in hair, the pigmented tissue underlying the iris of the eye, and the stria vascularis of the inner ear. In the brain, tissues with melanin include the medulla and pigment-bearing neurons within areas of the brainstem, such as the locus coeruleus and the substantia nigra. It also occurs in the zona reticularis of the adrenal gland. The melanin in the skin is produced by melanocytes, which are found"
"of people in the world have skin that is a shade of brown, from a very light honey brown or a golden brown, to a copper or bronze color, to a coffee color or a dark chocolate brown. Skin color and race are not the same; many people classified as ""white"" or ""black"" actually have skin that is a shade of brown. Brown skin is caused by melanin, a natural pigment which is produced within the skin in cells called melanocytes. Skin pigmentation in humans evolved to primarily regulate the amount of ultraviolet radiation penetrating the skin, controlling its biochemical"
"absorbed by the pigment, but instead are reflected. Biological pigments include plant pigments and flower pigments. Animals can appear colored due to two mechanisms, pigments and structural colors. Animals may have both biological pigments and structural colors, for example, some butterflies with white wings. Many animal body-parts, such as skin, eyes, feathers, fur, hair, scales and cuticles, contain pigments in specialized cells called chromatophores. These cells are found in a wide range of animals including amphibians, fish, reptiles, crustaceans and cephalopods. Mammals and birds, in contrast, have a class of cells called melanocytes for colouration. The term chromatophore can also"
"Pigment A pigment is a material that changes the color of reflected or transmitted light as the result of wavelength-selective absorption. This physical process differs from fluorescence, phosphorescence, and other forms of luminescence, in which a material emits light. Most materials selectively absorb certain wavelengths of light. Materials that humans have chosen and developed for use as pigments usually have special properties that make them useful for coloring other materials. A pigment must have a high tinting strength relative to the materials it colors. It must be stable in solid form at ambient temperatures. For industrial applications, as well as"
"Melanocyte Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. Through a process called melanogenesis, melanocytes produce melanin, which is a pigment found in the skin, eyes,"
"healthier, sexier and more powerful."" The authors of these books all present roughly similar ideas. Most agree, for example, on the following basic points: Chase explored the impact of skin pigments on coloration. She noted that there are three primary pigments that give the skin its tone: ""Melanin, which gives the skin its brown tones; carotene imparts the yellow/orange skin tones; and hemoglobin is the red pigment in the blood, which gives the skin its pink and red hues...The three pigments--melanin, carotene, and hemoglobin join one another to produce our flesh tones."" Bernice Kentner, who had worked as a licensed"
"pigmentation in their skin. The layers (from furthest within to the outer layer) consists of red, yellow, black, iridescent (blue and green), and metallic (not a colour of its own, but reacts with the other colours to change how they are perceived). Any combination of these layers can be present, leading to a wide variety of colours. The shades of blue, turquoise, and green are slightly iridescent, and can appear to change colour with different lighting conditions or viewing angles; this is because these colours (unlike black or red) are not due to pigments, but created through refraction within a"
"Ommochrome Ommochrome (or visual pigment) refers to several biological pigments that occur in the eyes of crustaceans and insects. The eye color is determined by the ommochromes. Ommochromes are also found in the chromatophores of cephalopods, and in spiders. Ommochromes are metabolites of tryptophan, via kynurenine and 3-hydroxykynurenine. They are responsible for a wide variety of colors, ranging from yellow over red and brown to black. Lighter colors tend to be generated by ommatins, while mixtures of ommatin and ommins are responsible for darker colors. In spiders, ommochromes are usually deposited as pigment granules within the cells of the hypodermis,"
"immediately beneath the cuticle. Ommochrome Ommochrome (or visual pigment) refers to several biological pigments that occur in the eyes of crustaceans and insects. The eye color is determined by the ommochromes. Ommochromes are also found in the chromatophores of cephalopods, and in spiders. Ommochromes are metabolites of tryptophan, via kynurenine and 3-hydroxykynurenine. They are responsible for a wide variety of colors, ranging from yellow over red and brown to black. Lighter colors tend to be generated by ommatins, while mixtures of ommatin and ommins are responsible for darker colors. In spiders, ommochromes are usually deposited as pigment granules within the"
"Melanin Melanin (; from ""melas"", ""black, dark"") is a broad term for a group of natural pigments found in most organisms. Melanin is produced by the oxidation of the amino acid tyrosine, followed by polymerization. The melanin pigments are produced in a specialized group of cells known as melanocytes. There are three basic types of melanin: eumelanin, pheomelanin, and neuromelanin. The most common type is eumelanin, of which there are two types—brown eumelanin and black eumelanin. Pheomelanin is a cysteine-derivative that contains polybenzothiazine portions that are largely responsible for the color of red hair, among other pigmentation. Neuromelanin is found"
"of people with light skin is determined mainly by the bluish-white connective tissue under the dermis and by the hemoglobin circulating in the veins of the dermis. The red color underlying the skin becomes more visible, especially in the face, when, as consequence of physical exercise or the stimulation of the nervous system (anger, fear), arterioles dilate. There are at least five different pigments that determine the color of the skin. These pigments are present at different levels and places. There is a correlation between the geographic distribution of UV radiation (UVR) and the distribution of indigenous skin pigmentation around"
"changing cells that are directly stimulated by central motor neurons. They are primarily used for quick environmental adaptation for camouflaging. The process of changing the color pigment of their skin relies on a single highly developed chromatophore cell and many muscles, nerves, glail and sheath cells. Chromatophores contract and contain vesicles that stores three different liquid pigments. Each color is indicated by the three types of chromatophore cells: erythrophores, melanophores, and xanthophores. The first type is the erythrophores, which contains reddish pigments such as carotenoids and pteridines. The second type is the melanophores, which contains black and brown pigments such"
"cells called melanocytes and it is the main determinant of the skin color of darker-skinned humans. The skin color of people with light skin is determined mainly by the bluish-white connective tissue under the dermis and by the hemoglobin circulating in the veins of the dermis. The red color underlying the skin becomes more visible, especially in the face, when, as consequence of physical exercise or the stimulation of the nervous system (anger, fear), arterioles dilate. Color is not entirely uniform across an individual's skin; for example, the skin of the palm and the sole is lighter than most other"
"marketed worldwide. Asia has the highest rate on a quantity basis followed by Europe and North America. The global demand on pigments was roughly US$20.5 billion in 2009. Pigments appear colored because they selectively reflect and absorb certain wavelengths of visible light. White light is a roughly equal mixture of the entire spectrum of visible light with a wavelength in a range from about 375 or 400 nanometers to about 760 or 780 nm. When this light encounters a pigment, parts of the spectrum are absorbed by the pigment. Organic pigments such as diazo or phthalocyanine compounds feature conjugated systems"
"that underlie the addiction. The term ""tanning"" has a cultural origin, arising from the color tan. Its origin lies in the Western culture of Europe when it became fashionable for young women to seek a less pale complexion (see Cultural history below). Melanin is a natural pigment produced by cells called melanocytes in a process called melanogenesis. Melanocytes produce two types of melanin: pheomelanin (red) and eumelanin (very dark brown). Melanin protects the body by absorbing ultraviolet radiation. Excessive UV radiation causes sunburn along with other direct and indirect DNA damage to the skin, and the body naturally combats and"
"Respiratory pigment A respiratory pigment is a molecule, such as hemoglobin in humans and other vertebrates, that increases the oxygen-carrying capacity of the blood. The four most common invertebrate respiratory pigments are hemoglobin, hemocyanin, hemerythrin and chlorocruorin. Hemoglobin is bright red when oxygenated, and dark red(purplish) when deoxygenated, oxygenated hemocyanin is blue in colour, deoxygenated it is almost colourless. Oxygenated chlorocruorin turns from green to red, whereas oxygenated hemerythrin is a violet to pink colour and colourless when deoxygenated. Any of various coloured conjugated proteins, such as hemoglobin, occur in living organisms and function in oxygen transfer in cellular respiration."
"Respiratory pigment A respiratory pigment is a molecule, such as hemoglobin in humans and other vertebrates, that increases the oxygen-carrying capacity of the blood. The four most common invertebrate respiratory pigments are hemoglobin, hemocyanin, hemerythrin and chlorocruorin. Hemoglobin is bright red when oxygenated, and dark red(purplish) when deoxygenated, oxygenated hemocyanin is blue in colour, deoxygenated it is almost colourless. Oxygenated chlorocruorin turns from green to red, whereas oxygenated hemerythrin is a violet to pink colour and colourless when deoxygenated. Any of various coloured conjugated proteins, such as hemoglobin, occur in living organisms and function in oxygen transfer in cellular respiration."
"debromohymenialdisine have several lead compounds in the field of inflammation, rheumatoid arthritis and osteoarthritis respectively. There’s evidence that topsentins are potent mediators of immunogenic inflation, and topsentin and scytonemin are potent inhibitors of neurogenic inflammation. Pigments may be extracted and used as dyes. Pigments (such as astaxanthin and lycopene) are used as dietary supplements. Biological pigment Biological pigments, also known simply as pigments or biochromes, are substances produced by living organisms that have a color resulting from selective color absorption. Biological pigments include plant pigments and flower pigments. Many biological structures, such as skin, eyes, feathers, fur and hair contain"
"layers of their skin. The top layer contains 'xanthophores' with orange, red, or yellow pigments; the middle layer contains 'iridophores' with a silvery light-reflecting pigment; while the bottom layer contains 'melanophores' with dark melanin. While many animals are unable to synthesize carotenoid pigments to create red and yellow surfaces, the green and blue colours of bird feathers and insect carapaces are usually not produced by pigments at all, but by structural coloration. Structural coloration means the production of colour by microscopically-structured surfaces fine enough to interfere with visible light, sometimes in combination with pigments: for example, peacock tail feathers are"
"used to discover the true colors of fossil ""Anchiornis huxleyi"" by the Beijing Museum of Natural History. Melanosomes are believed to template melanin polymerization by way of amyloidogenesis of the protein Pmel17, which is present in abundant quantities in melanosomes. Melanosome A melanosome is an organelle found in animal cells and is the site for synthesis, storage and transport of melanin, the most common light-absorbing pigment found in the animal kingdom. Melanosomes are responsible for color and photoprotection in animal cells and tissues. Melanosomes are synthesised in the skin in melanocyte cells, as well as the eye in choroidal melanocytes"
"of polymer bonds. The two types are black eumelanin and brown eumelanin. Black eumelanin is the darkest; brown eumelanin is much lighter than black. A small amount of black eumelanin in the absence of other pigments causes grey hair. A small amount of brown eumelanin in the absence of other pigments causes yellow (blond) color hair. Often, natural blond or red hair will darken to a brown color over time. Brown-haired people have medium-thick strands of hair. Brown-haired people are thought to produce more skin-protecting eumelanin and are associated with having a more even skin tone. The range of skin"
"causing these cells to differentiate into melanocytes for the skin. Melanocyte Melanocytes are melanin-producing neural crest-derived cells located in the bottom layer (the stratum basale) of the skin's epidermis, the middle layer of the eye (the uvea), the inner ear, vaginal epithelium, meninges, bones, and heart. Melanin is a dark pigment primarily responsible for skin color. Once synthesized, melanin is contained in special organelles called melanosomes which can be transported to nearby keratinocytes to induce pigmentation. Functionally, melanin serves as protection against UV radiation. Melanocytes also have a role in the immune system. Through a process called melanogenesis, melanocytes produce"
"color change is due to MSH stimulating the dispersion of melanin pigment in dermal (skin) melanophore cells. Pars intermedia Pars intermedia is the boundary between the anterior and posterior lobes of the pituitary. It contains three types of cells - basophils, chromophobes, and colloid-filled cysts. The cysts are the remainder of Rathke’s pouch. In human fetal life, this area produces melanocyte stimulating hormone or MSH which causes the release of melanin pigment in skin melanocytes (pigment cells). However, the pars intermedia is normally either very small or entirely absent in adulthood. In lower vertebrates (fish, amphibians) MSH from the pars"
"in the brain, though its function remains obscure. In the human skin, melanogenesis is initiated by exposure to UV radiation, causing the skin to darken. Melanin is an effective absorbent of light; the pigment is able to dissipate over 99.9% of absorbed UV radiation. Because of this property, melanin is thought to protect skin cells from UVB radiation damage, reducing the risk of cancer, and it is considered that exposure to UV radiation is associated with increased risk of malignant melanoma, a cancer of melanocytes (melanin cells). Studies have shown a lower incidence for skin cancer in individuals with more"
"of melanins considering that they are an aggregate of smaller component molecules, such as nitrogen containing melanins. There are two classes of pigments: black and brown insoluble eumelanins, which are derived from aerobic oxidation of tyrosine in the presence of tyrosinase, and the alkali-soluble phaeomelanins which range from a yellow to red brown color, arising from the deviation of the eumelanin pathway through the intervention of cysteine and/or glutathione. Eumelanins are usually found in the skin and eyes. Several different melanins include melanoprotein (dark brown melanin that is stored in high concentrations in the ink sac of the cuttlefish Sepia"
"Depigmentation Depigmentation is the lightening of the skin, or loss of pigment. Depigmentation of the skin can be caused by a number of local and systemic conditions. The pigment loss can be partial (injury to the skin) or complete (caused by vitiligo). It can be temporary (from tinea versicolor) or permanent (from albinism). Most commonly, depigmentation of the skin is linked to people born with vitiligo, which produces differing areas of light and dark skin. These individuals, if they so decided to use a lightening process to even out their skin tone, could apply a topical cream containing the organic"
"cartilage. The pigments can also be incorporated into collagen and elastin fibers. In the skin, the pigment alters the structure of the fibers, causing enlargement and curling. The embedded pigments also form crosslinks with pigment depositions in adjacent fibers, stabilizing and reducing the elastic recoil of the fibers. This results in hardening of elastic structures, increasing their rigidity and brittleness. Once ruptured, the exposed pigments cause a foreign body reaction and inflammation. This pigment deposition also invokes deposition of hydroxyapatite, the mineral responsible for bone calcification, further hardening the connective tissue. The pigment can also be excreted by glandular cells"
"due to the stratum corneum and is critical for maintaining healthy skin. Lipids arranged through a gradient and in an organized manner between the cells of the stratum corneum form a barrier to transepidermal water loss. The amount and distribution of melanin pigment in the epidermis is the main reason for variation in skin color in ""Homo sapiens"". Melanin is found in the small melanosomes, particles formed in melanocytes from where they are transferred to the surrounding keratinocytes. The size, number, and arrangement of the melanosomes vary between racial groups, but while the number of melanocytes can vary between different"
"""Agouti"" encodes for a protein, the Agouti signalling peptide (ASP), which specifically inhibits the action of the Melanocortin 1 receptor (MC1R). In the absence of the Agouti protein, alpha-melanocyte-stimulating hormone stimulates the cells bearing MC1R, melanocytes, to produce dark eumelanin, colouring the skin and fur dark brown or black. In the presence of the Agouti protein, the same system produces the lighter-coloured, yellow or red phaeomelanin. A genetic switch active in the cells of the embryo that will become the belly skin causes the ""Agouti"" gene to become active there, creating the countershading seen in adult mammals. If countershading paints"