"Articular cartilage damage Cartilage structures and functions can be damaged. Such damage can result from a variety of causes, such as a bad fall or traumatic sport-accident, previous knee injuries or wear and tear over time. Immobilization for long periods can also result in cartilage damage. Articular cartilage damage in the knee may be found on its own but it will more often be found in conjunction with injuries to ligaments and menisci. People with previous surgical interventions face more chances of articular cartilage damage due to altered mechanics of the joint. Articular cartilage damage may also be found in"
"Cartilage Cartilage is a resilient and smooth elastic tissue, a rubber-like padding that covers and protects the ends of long bones at the joints, and is a structural component of the rib cage, the ear, the nose, the bronchial tubes, the intervertebral discs, and many other body components. It is not as hard and rigid as bone, but it is much stiffer and much less flexible than muscle.The matrix of cartilage is made up of chondrin. Because of its rigidity, cartilage often serves the purpose of holding tubes open in the body. Examples include the rings of the trachea, such"
"Meniscus (anatomy) A meniscus is a crescent-shaped fibrocartilaginous anatomical structure that, in contrast to an articular disk, only partly divides a joint cavity. In humans they are present in the knee, wrist, acromioclavicular, sternoclavicular, and temporomandibular joints; in other animals they may be present in other joints. Generally, the term 'meniscus' is used to refer to the cartilage of the knee, either to the lateral or medial meniscus. Both are cartilaginous tissues that provide structural integrity to the knee when it undergoes tension and torsion. The menisci are also known as ""semi-lunar"" cartilages, referring to their half-moon, crescent shape. The"
"Types of articular surfaces include trochlear surfaces. Joints can also be classified based on their anatomy or on their biomechanical properties. According to the anatomic classification, joints are subdivided into ""simple"" and ""compound"", depending on the number of bones involved, and into ""complex"" and ""combination"" joints: The joints may be classified anatomically into the following groups: Damaging the cartilage of joints (articular cartilage) or the bones and muscles that stabilize the joints can lead to joint dislocations and osteoarthritis. Swimming is a great way to exercise the joints with minimal damage. A joint disorder is termed arthropathy, and when involving"
"to their fine and complex structure. A ""sinus"" refers to a bony cavity, usually within the skull. A joint, or articulation is the region where adjacent bones contact each other, for example the elbow, shoulder, or costovertebral joint. Terms that refer to joints include: Bones are commonly described with the terms ""head"", ""neck"", ""shaft"", ""body"" and ""base"" The ""head"" of a bone usually refers to the proximal end of the bone. The shaft refers to the elongated sections of long bone, and the ""neck"" the segment between the head and shaft (or body). The end of the long bone opposite"
"may involve tendon sheaths and bursal sacs. Cartilaginous intra-articular bodies float freely within the synovial fluid, which they require for nutrition and growth. Progressive enlargement and ossification occur with time. If they remain free, they continue to grow larger and more calcified. In severe cases, they may occupy the entire joint space or penetrate to adjacent tissues. Also, they can deposit in the synovial lining, reestablish a blood supply, and become replaced by bone. On occasion, synovial reattachment can lead to complete reabsorption of the cartilage fragment. Chronic, progressive pain and swelling of the affected joint are exacerbated by physical"
"ribs. Known as ""symphysis"". Fibrocartilaginous and hyaline joints, usually occurring in the midline. Examples in human anatomy would be the manubriosternal joint (between the manubrium and the sternum), intervertebral discs, and the pubic symphysis. Articulating bones at a symphysis are covered with hyaline cartilage and have a thick, fairly compressible pad of fibrocartilage between them. Cartilaginous joints allow little movement, as summarized above. Cartilaginous joint Cartilaginous joints are connected entirely by cartilage (fibrocartilage or hyaline). Cartilaginous joints allow more movement between bones than a fibrous joint but less than the highly mobile synovial joint. Cartilaginous joints also forms the growth"
"synthetic cartilage to be used in joint spaces, high mechanical strength under compression needs to be an intrinsic property of the material. There are three types of cartilage in the human body: fibrocartilage, hyaline cartilage and elastic cartilage. Each type of cartilage has varying concentrations of components such as proteoglycans, collagen and water which determine its functional properties and location in the body. Fibrocartilage is most often found in the intervertebral discs, elastic cartilage is found in the external ear and hyaline cartilage is found on many joint surfaces in the body. Replacement of hyaline cartilage (articular cartilage) is the"
"Synchondrosis Where the connecting medium is hyaline cartilage, a cartilaginous joint is termed a synchondrosis. An example of a synchondrosis joint is the first sternocostal joint (where the first rib meets the manubrium). In this example, the rib articulates with the manubrium via the costal cartilage. (The rest of the sternocostal joints are synovial plane joints.) Sometimes, this is a temporary form of joint called epiphyseal growth plate, where the cartilage is converted into bone before adult life. Such joints are found between the epiphyses and diaphyses of long bones, between the occipital and the sphenoid, and for some years"
"degenerative knee disease. The term meniscus derives from Greek μηνίσκος ""meniskos"", ""crescent moon"". The word was also used for curved things in general, such as a necklace or a line of battle. Meniscus (anatomy) A meniscus is a crescent-shaped fibrocartilaginous anatomical structure that, in contrast to an articular disk, only partly divides a joint cavity. In humans they are present in the knee, wrist, acromioclavicular, sternoclavicular, and temporomandibular joints; in other animals they may be present in other joints. Generally, the term 'meniscus' is used to refer to the cartilage of the knee, either to the lateral or medial meniscus."
"after birth, between the petrous portion of the temporal and the jugular process of the occipital bone. Synchondrosis Where the connecting medium is hyaline cartilage, a cartilaginous joint is termed a synchondrosis. An example of a synchondrosis joint is the first sternocostal joint (where the first rib meets the manubrium). In this example, the rib articulates with the manubrium via the costal cartilage. (The rest of the sternocostal joints are synovial plane joints.) Sometimes, this is a temporary form of joint called epiphyseal growth plate, where the cartilage is converted into bone before adult life. Such joints are found between"
"deposition, but can also refer to both the growth and remodeling of the extracellular matrix. Due to the great stress on the patellofemoral joint during resisted knee extension, the articular cartilage of the patella is among the thickest in the human body. The mechanical properties of articular cartilage in load bearing joints such as knee and hip have been studied extensively at macro, micro and nano-scales. These mechanical properties include the response of cartilage in frictional, compressive, shear and tensile loading. Cartilage is resilient and displays viscoelastic properties. Lubricin, a glycoprotein abundant in cartilage and synovial fluid, plays a major"
"Joint A joint or articulation (or articular surface) is the connection made between bones in the body which link the skeletal system into a functional whole. They are constructed to allow for different degrees and types of movement. Some joints, such as the knee, elbow, and shoulder, are self-lubricating, almost frictionless, and are able to withstand compression and maintain heavy loads while still executing smooth and precise movements. Other joints such as sutures between the bones of the skull permit very little movement (only during birth) in order to protect the brain and the sense organs. The connection between a"
"This structure formed is porous and therefore firm and at the same time light. It coalesces into small calcareous ossicles (bony plates), which can grow in all directions and thus can replace the loss of a body part. Connected by joints, the individual skeletal parts can be moved by the muscles. In most vertebrates, the main skeletal component is referred to as bone. These bones compose a unique skeletal system for each type of animal. Another important component is cartilage which in mammals is found mainly in the joint areas. In other animals, such as the cartilaginous fishes, which include"
"Crepitus Crepitus (; also termed crepitation) is a medical term to describe the grating, crackling or popping sounds and sensations experienced under the skin and joints or a crackling sensation due to the presence of air in the subcutaneous tissue. Various types of crepitus that can be heard in joint pathologies are: The sound can be created when two rough surfaces in an organism's body come into contact—for example, in osteoarthritis or rheumatoid arthritis when the cartilage around joints erodes and the surfaces in the joint grind against one another, or when the fractured surfaces of two broken bones rub"
"Cartilage will wear over the years. Cartilage has a very limited capacity for self-restoration. The newly formed tissue will generally consist of a large part of fibrous cartilage of lesser quality than the original hyaline cartilage. As a result, new cracks and tears will form in the cartilage over time. The articular disks of the knee-joint are called menisci because they only partly divide the joint space. These two disks, the medial meniscus and the lateral meniscus, consist of connective tissue with extensive collagen fibers containing cartilage-like cells. Strong fibers run along the menisci from one attachment to the other,"
"provide stability and facilitate movement. Two filmy sac-like structures called bursae permit smooth gliding between bone, muscle, and tendon. They cushion and protect the rotator cuff from the bony arch of the acromion. The glenoid labrum is the second kind of cartilage in the shoulder which is distinctly different from the articular cartilage. This cartilage is more fibrous or rigid than the cartilage on the ends of the ball and socket. Also, this cartilage is also found only around the socket where it is attached. The shoulder joint (also known as the glenohumeral joint) is the main joint of the"
"term for a joint, any disease of a joint (or specifically degenerative joint disease), and is also used as a synonym for osteoarthritis. In the specialized literature that has evolved around TMD research, arthrosis is differentiated from arthritis by the presence of low and no inflammation respectively. Both are however equally degenerative. The TMJs are sometimes described as one of the most used joints in the body. Over time, either with normal use or with parafunctional use of the joint, wear and degeneration can occur, termed osteoarthritis. Rheumatoid arthritis, an autoimmune joint disease, can also affect the TMJs. Degenerative joint"
"cartilage for use in repairing torn tissue. The cartilage is injected into a wound or damaged joint and will harden with exposure to ultraviolet light. Researchers say their lubricating layers of ""molecular brushes"" can outperform nature under the highest pressures encountered within joints, with potentially important implications for joint replacement surgery. Each 60-nanometre-long brush filament has a polymer backbone from which small molecular groups stick out. Those synthetic groups are very similar to the lipids found in cell membranes. ""In a watery environment, each of these molecular groups attracts up to 25 water molecules through electrostatic forces, so the filament"
"the avascular cartilage. In any one position, much of the cartilage is close enough to get nutrition directly from the synovium. Some areas of cartilage have to obtain nutrients indirectly and may do so either from diffusion through cartilage or possibly by 'stirring' of synovial fluid. The surface of synovium may be flat or may be covered with finger-like projections or villi, which, it is presumed, help to allow the soft tissue to change shape as the joint surfaces move one on another. The synovial fluid can be thought of as a specialised fluid form of synovial extracellular matrix rather"
"of the x-ray. Cartilaginous fish (chondrichthyes) like sharks, rays and skates have a skeleton composed entirely of cartilage. Cartilage tissue can also be found among some arthropods such as horseshoe crabs, some mollusks such as marine snails and cephalopods, and some annelids like sabellid polychaetes. Arthropods The most studied cartilage in arthropods is the ""Limulus polyphemus"" branchial cartilage. It is a vesicular cell-rich cartilage due to the large, spherical and vacuolated chondrocytes with no homologies in other arthropods. Other type of cartilage found in ""Limulus polyphemus"" is the endosternite cartilage, a fibrous-hyaline cartilage with chondrocytes of typical morphology in a"
"knee is a modified hinge joint, a type of synovial joint, which is composed of three functional compartments: the patellofemoral articulation, consisting of the patella, or ""kneecap"", and the patellar groove on the front of the femur through which it slides; and the medial and lateral tibiofemoral articulations linking the femur, or thigh bone, with the tibia, the main bone of the lower leg. The joint is bathed in synovial fluid which is contained inside the synovial membrane called the joint capsule. The posterolateral corner of the knee is an area that has recently been the subject of renewed scrutiny"
"being a snug fit, it is a loose fit, or a partial fit. Secondly, the caput or acetabulum are not smooth and round, but are misshapen, causing abnormal wear and tear or friction within the joint as it moves. The body reacts to this in several ways. First, the joint itself is continually repairing itself and laying down new cartilage. However, cartilage repair is a relatively slow process, the tissue being avascular, so the joint may suffer degradation due to the abnormal wear and tear, or may not support the body weight as intended. The joint becomes inflamed and a"
"ilium, ischium, and pubis. This cartilage ossifies as the child grows. The word acetabulum literally means ""little vinegar cup"". It was the Latin word for a small vessel for serving vinegar. The word was later also used as a unit of volume. Acetabulum The acetabulum (cotyloid cavity) is a concave surface of a pelvis. The head of the femur meets with the pelvis at the acetabulum, forming the hip joint. There are three bones of the os coxae (hip bone) that come together to form the acetabulum. Contributing a little more than two-fifths of the structure is the ischium, which"
"procedures, ongoing research is looking into underlying problems which may increase the likelihood of an athlete suffering a severe knee injury. These findings may lead to effective preventive measures, especially in female athletes, who have been shown to be especially vulnerable to ACL tears from relatively minor trauma. Articular cartilage repair treatment: In humans, the term ""knee"" refers to the joints between the femur, tibia, and patella, in the leg. In quadrupeds such as dogs, horses, and mice, the homologous joints between the femur, tibia, and patella, in the hind leg, are known as the stifle joint. Also in quadrupeds,"
"cartilage. In 16th-century Italian anatomist Realdo Colombo's ""De re anatomica"", besides the aforementioned incorrect ""petalis cartilago"", correct forms like ""scutalis cartilago"" and ""scutiformis cartilago"" can be found, as the ""scutum"" is the real Roman pendant of the Greek θυρεός. The latter Latin expression can be found in its English form in medical dictionaries as ""scutiform cartilage"", while the name of the shield itself, i.e. ""scutum"", is still being mentioned as a synonym for the thyroid cartilage. In the various editions of the official Latin nomenclature (""Nomina Anatomica"", in 1998 rebaptized as ""Terminologia Anatomica""), three different spellings can be found, i.e."
"partially cartilagenous, or consist of multiple bony elements. In the early tetrapods, these two structures respectively became the scapula and a bone referred to as the procoracoid (commonly called simply the ""coracoid"", but not homologous with the mammalian structure of that name). In amphibians and reptiles (birds included), these two bones are distinct, but together form a single structure bearing many of the muscle attachments for the forelimb. In such animals, the scapula is usually a relatively simple plate, lacking the projections and spine that it possesses in mammals. However, the detailed structure of these bones varies considerably in living"
"flexible chitin is the major structural part of the integument where flexibility is necessary, such as in bodily parts that must stretch to contain accumulated liquids, or that form joints between rigid parts of the exoskeleton. In other parts of the cuticle the function of the integument demands more rigid materials, such as armoured regions or the biting parts of the jaws, or where the exoskeleton forms the tubular limbs of most Arthropoda. To achieve such rigidity the outer chitin layer of the cuticle is impregnated, thickened, and reinforced with harder, more brittle materials such as sclerotinised proteins or calcite."
"flaps. Hinge joint A hinge joint (ginglymus) is a bone joint in which the articular surfaces are molded to each other in such a manner as to permit motion only in one plane. According to one classification system they are said to be uniaxial (having one degree of freedom). The direction which the distal bone takes in this motion is seldom in the same plane as that of the axis of the proximal bone; there is usually a certain amount of deviation from the straight line during flexion. The articular surfaces of the bones are connected by strong collateral ligaments."
"Knee cartilage replacement therapy Articular cartilage, most notably that which is found in the knee joint, is generally characterized by very low friction, high wear resistance, and poor regenerative qualities. It is responsible for much of the compressive resistance and load bearing qualities of the knee joint and, without it, walking is painful to impossible. Osteoarthritis is a common condition of cartilage failure that can lead to limited range of motion, bone damage and invariably, pain. Due to a combination of acute stress and chronic fatigue, osteoarthritis directly manifests itself in a wearing away of the articular surface and, in"
"fibrils) and proteoglycans. The ratio and the proportion of collagen play an important role in the tensile and compressive strength, as well as the elasticity of the tissue. The content of collagen in cartilage is different between joints and soft tissue structures. For example, cartilage in the knee has a different structure to the ankle. Cartilage, skin, and spinal discs are subject to continuous regeneration during which anabolic and catabolic processes are in equilibrium. Any imbalance in this equilibrium between matrix degeneration and regeneration results in a decrease in the components of the ECM, and leads to loss of chondral"
"as the cricoid cartilage and carina. Cartilage is composed of specialized cells called chondrocytes that produce a large amount of collagenous extracellular matrix, abundant ground substance that is rich in proteoglycan and elastin fibers. Cartilage is classified in three types, ""elastic cartilage"", ""hyaline cartilage"" and ""fibrocartilage"", which differ in relative amounts of collagen and proteoglycan. Cartilage does not contain blood vessels (it is avascular) or nerves (it is aneural). Nutrition is supplied to the chondrocytes by diffusion. The compression of the articular cartilage or flexion of the elastic cartilage generates fluid flow, which assists diffusion of nutrients to the chondrocytes."
"joints, causing stiffness in the neck, jaw, shoulders, hips and knees. Spondylitis Spondylitis is an inflammation of the vertebra. It is a form of spondylopathy. In many cases spondylitis involves one or more vertebral joints as well, which itself is called spondylarthritis. Pott's disease is a tuberculous disease of the vertebrae marked by stiffness of the vertebral column, pain on motion, tenderness on pressure, prominence of certain vertebral spines, and occasionally abdominal pain, abscess formation, and paralysis. Ankylosing spondylitis is an inflammatory disease involving the spine and sacroiliac joints, and is therefore also a form of spondylarthritis. A combination of"