Primal Defense. Primal Defense is the only microbiome formula that includes a unique food blend with Homeostatic® Soil Organisms (HSOs), important microbiomes you’d only get in abundance if your food came from soil untouched by pesticides, herbicides and other widely used chemicals. Primal Defense includes 12 specific of beneficial microorganisms - let the unique HSOs in Primal Defense take you to a new level of health.