The makers of Cointreau are marking 2018 as the 70th anniversary of the creation of the margarita cocktail, which was first crafted with tequila, triple sec (orange flavored liqueur such as Cointreau) and lime. Their reciped for the Original Margarita calls for 2 ounces blanco tequila, 1 ounce Cointreau and 1 ounce fresh lime juice.