A SHOT at better blood transfusion (source: National Health Executive Jul/Aug 2012) In 2011, there were no cases of transfusion transmitted infections (TTI) Acute Transfusion Reactions (ATR) was the leading cause of major morbidity in 2011 and there was also a high level of Transfusion Associated Circulatory Overload (TACO) While death rates due to blood transfusion complications and errors are rare and getting rarer, near miss events still happen with alarming frequency About half of all the reports are of adverse events caused by errors, which should all be preventable.