A man holds a sign urging increased access to the monkeypox vaccine during a protest in San Francisco, July 18, 2022. The mayor of San Francisco announced a legal state of emergency Thursday, July 28, 2022, over the growing number of monkeypox cases. The declaration allows officials to mobilize personnel and cut through red tape to get ahead of a public health crisis all too reminiscent of the AIDS epidemic that devastated San Francisco in the 1980s. (AP Photo/Haven Daley)