3 Metaanalysis on Heparin & LMWH in APS 0.1 Rai et al, 1.88 (1.15-3.08) Kutteh et al, 2.45 (1.11-5.44) Farquharson et al, 1.18 (0.73-1.91) Overall, 1.65 (1.2-2.27) 101 n No measurement of  2 GP-1 antibodies n No correction for chromosomal aberrations n No correction for embryonic structural malformations n Overall benefit 22%