Rheumatoid vasculitis (RV) is destructive inflammation of the blood vessel wall that adds substantial morbidity to a diagnosis of RA. RV usually develops late in the course of RA, when disease burden is high. RV may affect a wide range of blood vessel types, from medium-sized muscular arteries to somewhat smaller arterioles to postcapillary venules. RV leads to necrosis, blood vessel occlusion, and tissue ischemia in a manner that resembles other forms of systemic vasculitis, particularly polyarteritis nodosa.