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Sinusitis
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For the joint inflammation condition, see Synovitis.
Sinusitis
Synonyms
Sinus infection, rhinosinusitis
Left-sided maxillary sinusitis marked by an arrow. Note the lack of the air transparency indicating fluid in contrast to the other side.
Specialty
Otorhinolaryngology
Symptoms
Thick nasal mucus, plugged nose, pain in the face, fever[1][2][3]
Causes
Infection (bacterial, fungal), allergies, air pollution, structural problems in the nose[2]
Risk factors
Asthma, cystic fibrosis, poor immune function[1]
Diagnostic method
Usually based on symptoms[1]
Similar conditions
Migraine[4]
Prevention
Handwashing, avoiding smoking, immunization[2]
Treatment
Pain medications, nasal steroids, nasal irrigation, antibiotic[1][5]
Frequency
10–30% each year (developed world)[1][6]
[edit on Wikidata]
Sinusitis, also known as a sinus infection or rhinosinusitis, is inflammation of the sinuses resulting in symptoms.[1] Common signs and symptoms include thick nasal mucus, a plugged nose, and pain in the face.[1] Other signs and symptoms may include fever, headaches, poor sense of smell, sore throat, and cough.[2][3] The cough is often worse at night.[3] Serious complications are rare.[3] It is defined as acute rhinosinusitis (ARS) if it lasts less than 4 weeks, and as chronic rhinosinusitis (CRS) if it lasts for more than 12 weeks.[1]
Sinusitis can be caused by infection, allergies, air pollution, or structural problems in the nose.[2] Most cases are caused by a viral infection.[2] A bacterial infection may be present if symptoms last more than ten days or if a person worsens after starting to improve.[1] Recurrent episodes are more likely in people with asthma, cystic fibrosis, and poor immune function.[1] X-rays are not typically needed unless complications are suspected.[1] In chronic cases confirmatory testing is recommended by either direct visualization or computed tomography.[1]
Some cases may be prevented by hand washing, avoiding smoking, and immunization.[2] Pain killers such as naproxen, nasal steroids, and nasal irrigation may be used to help with symptoms.[1][5] Recommended initial treatment for ARS is watchful waiting.[1] If symptoms do not improve in 7–10 days or get worse, then an antibiotic may be used or changed.[1] In those in whom antibiotics are used, either amoxicillin or amoxicillin/clavulanate is recommended first line.[1] Surgery may occasionally be used in people with chronic disease.[7]
Sinusitis is a common condition.[1] It affects between about 10% and 30% of people each year in the United States and Europe.[1][6] Women are more often affected than men.[8] Chronic sinusitis affects approximately 12.5% of people.[9] Treatment of sinusitis in the United States results in more than 11 billion USD in costs.[1] The unnecessary and ineffective treatment of viral sinusitis with antibiotics is common.[1]
Contents
[hide]
1 Categories
2 Signs and symptoms
2.1 By location
2.2 Complications
3 Causes
3.1 Acute
3.2 Chronic
4 Pathophysiology
5 Diagnosis
5.1 Acute
5.2 Chronic
6 Treatment
6.1 Antibiotics
6.2 Corticosteroids
6.3 Surgery
7 Epidemiology
8 Research
9 See also
10 References
11 External links
Categories[edit]
Illustration depicting sinusitis
Sinusitis (or rhinosinusitis) is defined as an inflammation of the mucous membrane that lines the paranasal sinuses and is classified chronologically into several categories:[10]
Acute rhinosinusitis – A new infection that may last up to four weeks and can be subdivided symptomatically into severe and non-severe. Some use definitions up to 12 weeks.[1]
Recurrent acute rhinosinusitis – Four or more full episodes of acute sinusitis that occur within one year
Subacute rhinosinusitis – An infection that lasts between four and 12 weeks, and represents a transition between acute and chronic infection
Chronic rhinosinusitis – When the signs and symptoms last for more than 12 weeks.[1]
Acute exacerbation of chronic rhinosinusitis – When the signs and symptoms of chronic rhinosinusitis exacerbate, but return to baseline after treatment
All these types of sinusitis have similar symptoms, and are thus often difficult to distinguish. Acute sinusitis is very common. Roughly ninety percent of adults have had sinusitis at some point in their life.[11]
Signs and symptoms[edit]
Headache/facial pain or pressure of a dull, constant, or aching sort over the affected sinuses is common with both acute and chronic stages of sinusitis. This pain is typically localized to the involved sinus and may worsen when the affected person bends over or when lying down. Pain often starts on one side of the head and progresses to both sides.[12] Acute sinusitis may be accompanied by thick nasal discharge that is usually green in color and may contain pus (purulent) and/or blood.[13] Often a localized headache or toothache is present, and it is these symptoms that distinguish a sinus-related headache from other types of headaches, such as tension and migraine headaches. Another way to distinguish between toothache and sinusitis is that the pain in sinusitis is usually worsened by tilting the head forwards and with valsalva maneuvers.[14]
Infection of the eye socket is possible, which may result in the loss of sight and is accompanied by fever and severe illness. Another possible complication is the infection of the bones (osteomyelitis) of the forehead and other facial bones – Pott's puffy tumor.[12]
Sinus infections can also cause middle ear problems due to the congestion of the nasal passages. This can be demonstrated by dizziness, "a pressurized or heavy head", or vibrating sensations in the head. Post-nasal drip is also a symptom of chronic rhinosinusitis.
Halitosis (bad breath) is often stated to be a symptom of chronic rhinosinusitis; however, gold standard breath analysis techniques have not been applied. Theoretically, there are several possible mechanisms of both objective and subjective halitosis that may be involved.[14]
A 2004 study suggested that up to 90% of "sinus headaches" are actually migraines.[15][16][verification needed] The confusion occurs in part because migraine involves activation of the trigeminal nerves, which innervate both the sinus region and the meninges surrounding the brain. As a result, it is difficult to accurately determine the site from which the pain originates. People with migraines do not typically have the thick nasal discharge that is a common symptom of a sinus infection.[17]
By location[edit]
There are several paired paranasal sinuses, including the frontal, ethmoidal, maxillary and sphenoidal sinuses. The ethmoidal sinuses are further subdivided into anterior and posterior ethmoid sinuses, the division of which is defined as the basal lamella of the middle turbinate. In addition to the severity of disease, discussed below, sinusitis can be classified by the sinus cavity which it affects:
Maxillary – can cause pain or pressure in the maxillary (cheek) area (e.g., toothache,[14] or headache) (J01.0/J32.0)
Frontal – can cause pain or pressure in the frontal sinus cavity (located above eyes), headache, particularly in the forehead (J01.1/J32.1)
Ethmoidal – can cause pain or pressure pain between/behind the eyes, the sides of the upper part of the nose (the medial canthi), and headaches (J01.2/J32.2)[18]
Sphenoidal – can cause pain or pressure behind the eyes, but often refers to the skull vertex (top of the head), over the mastoid processes, or the back of the head.[18]
Complications[edit]
Stage
Description
I Preseptal cellulitis
II Orbital cellulitis
III Subperiosteal abscess
IV Orbital abscess
V Cavernous sinus septic thrombosis
The proximity of the brain to the sinuses makes the most dangerous complication of sinusitis, particularly involving the frontal and sphenoid sinuses, infection of the brain by the invasion of anaerobic bacteria through the bones or blood vessels. Abscesses, meningitis and other life-threatening conditions may result. In extreme cases the patient may experience mild personality changes, headache, altered consciousness, visual problems, seizures, coma and possibly death.[12]
Sinus infection can spread through anastomosing veins or by direct extension to close structures. Orbital complications were categorized by Chandler et al.[19] into five stages according to their severity (see table). Contiguous spread to the orbit may result in periorbital cellulitis, subperiosteal abscess, orbital cellulitis, and abscess. Orbital cellulitis can complicate acute ethmoiditis if anterior and posterior ethmoidal veins thrombophlebitis enables the spread of the infection to the lateral or orbital side of the ethmoid labyrinth. Sinusitis may extend to the central nervous system, where it may cause cavernous sinus thrombosis, retrograde meningitis, and epidural, subdural, and brain abscesses.[20] Orbital symptoms frequently precede intracranial spread of the infection . Other complications include sinobronchitis, maxillary osteomyelitis, and frontal bone osteomyelitis.[21][22][23][24] Osteomyelitis of the frontal bone often originates from a spreading thrombo-phlebitis. A periostitis of the frontal sinus causes an osteitis and a periostitis of the outer membrane, which produces a tender, puffy swelling of the forehead.
The diagnosis of these complications can be assisted by noting local tenderness and dull pain, and can be confirmed by CT and nuclear isotope scanning. The most common microbial causes are anaerobic bacteria and S. aureus. Treatment includes performing surgical drainage and administration of antimicrobial therapy. Surgical debridement is rarely required after an extended course of parenteral antimicrobial therapy.[25] Antibiotics should be administered for at least 6 weeks. Continuous monitoring of patients for possible intracranial complication is advised.
Causes[edit]
Maxillary sinusitis may also be of dental origin ("odontogenic sinusitis"),[26] and constitutes a significant percentage (about 20% of all cases of maxillary sinusitis),[27] given the close proximity of the teeth and the sinus floor. The cause of this situation is usually a periapical or periodontal infection of a maxillary posterior tooth, where the inflammatory exudate has eroded through the bone superiorly to drain into the maxillary sinus. Once an odontogenic infection involves the maxillary sinus, it is possible that it may then spread to the orbit or to the ethmoid sinus.[27] Complementary tests based on conventional radiology techniques and modern technology may be indicated, based on the clinical context.
Chronic sinusitis can also be caused indirectly through a common but slight abnormality in the auditory or eustachian tube, which is connected to the sinus cavities and the throat. This tube is usually almost level with the eye sockets but when this sometimes hereditary abnormality is present, it is below this level and sometimes level with the vestibule or nasal entrance.
Acute[edit]
Acute sinusitis is usually precipitated by an earlier upper respiratory tract infection, generally of viral origin, mostly caused by rhinoviruses, coronaviruses, and influenza viruses, others caused by adenoviruses, human parainfluenza viruses, human respiratory syncytial virus, enteroviruses other than rhinoviruses, and metapneumovirus. If the infection is of bacterial origin, the most common three causative agents are Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis.[28] Until recently, Haemophilus influenzae was the most common bacterial agent to cause sinus infections. However, introduction of the H. influenza type B (Hib) vaccine has dramatically decreased H. influenza type B infections and now non-typable H. influenza (NTHI) are predominantly seen in clinics. Other sinusitis-causing bacterial pathogens include Staphylococcus aureus and other streptococci species, anaerobic bacteria and, less commonly, gram negative bacteria. Viral sinusitis typically lasts for 7 to 10 days,[28] whereas bacterial sinusitis is more persistent. Approximately 0.5% to 2% of viral sinusitis results in subsequent bacterial sinusitis. It is thought that nasal irritation from nose blowing leads to the secondary bacterial infection.[29]
Acute episodes of sinusitis can also result from fungal invasion. These infections are typically seen in patients with diabetes or other immune deficiencies (such as AIDS or transplant patients on immunosuppressive anti-rejection medications) and can be life-threatening. In type I diabetics, ketoacidosis can be associated with sinusitis due to mucormycosis.[30]
Chemical irritation can also trigger sinusitis, commonly from cigarette smoke and chlorine fumes.[31] Rarely, it may be caused by a tooth infection.[28]
Chronic[edit]
By definition chronic sinusitis lasts longer than 12 weeks and can be caused by many different diseases that share chronic inflammation of the sinuses as a common symptom. Symptoms of chronic sinusitis may include any combination of the following: nasal congestion, facial pain, headache, night-time coughing, an increase in previously minor or controlled asthma symptoms, general malaise, thick green or yellow discharge, feeling of facial 'fullness' or 'tightness' that may worsen when bending over, dizziness, aching teeth, and/or bad breath.[10] Each of these symptoms has multiple other possible causes, which should be considered and investigated as well. Often chronic sinusitis can lead to anosmia, the inability to smell objects.[10] In a small number of cases, acute or chronic maxillary sinusitis is associated with a dental infection. Vertigo, lightheadedness, and blurred vision are not typical in chronic sinusitis and other causes should be investigated.[citation needed]
Chronic sinusitis cases are subdivided into cases with polyps and cases without polyps. When polyps are present, the condition is called chronic hyperplastic sinusitis; however, the causes are poorly understood[28] and may include allergy, environmental factors such as dust or pollution, bacterial infection, or fungus (either allergic, infective, or reactive).
Chronic rhinosinusitis represents a multifactorial inflammatory disorder, rather than simply a persistent bacterial infection.[28] The medical management of chronic rhinosinusitis is now focused upon controlling the inflammation that predisposes patients to obstruction, reducing the incidence of infections. However, all forms of chronic rhinosinusitis are associated with impaired sinus drainage and secondary bacterial infections. Most individuals require initial antibiotics to clear any infection and intermittently afterwards to treat acute exacerbations of chronic rhinosinusitis.
A combination of anaerobic and aerobic bacteria are detected in conjunction with chronic sinusitis. Also isolated are Staphylococcus aureus (including methicilin resistant S.aureus ) and coagulase-negative Staphylococci and Gram negative enteric organisms can be isolated.
Attempts have been made to provide a more consistent nomenclature for subtypes of chronic sinusitis. The presence of eosinophils in the mucous lining of the nose and paranasal sinuses has been demonstrated for many patients, and this has been termed eosinophilic mucin rhinosinusitis (EMRS). Cases of EMRS may be related to an allergic response, but allergy is not often documented, resulting in further subcategorization into allergic and non-allergic EMRS.[32]
A more recent, and still debated, development in chronic sinusitis is the role that fungi play in this disease. It remains unclear if fungi are a definite factor in the development of chronic sinusitis and if they are, what the difference may be between those who develop the disease and those who remain free of symptoms. Trials of antifungal treatments have had mixed results.
Recent theories of sinusitis indicate that it often occurs as part of a spectrum of diseases that affect the respiratory tract (i.e., the "one airway" theory) and is often linked to asthma.[33][34] All forms of sinusitis may either result in, or be a part of, a generalized inflammation of the airway, so other airway symptoms, such as cough, may be associated with it.
Both smoking and secondhand smoke are associated with chronic rhinosinusitis.[9]
Pathophysiology[edit]
It has been hypothesized that biofilm bacterial infections may account for many cases of antibiotic-refractory chronic sinusitis.[35][36][37] Biofilms are complex aggregates of extracellular matrix and inter-dependent microorganisms from multiple species, many of which may be difficult or impossible to isolate using standard clinical laboratory techniques.[38] Bacteria found in biofilms have their antibiotic resistance increased up to 1000 times when compared to free-living bacteria of the same species. A recent study found that biofilms were present on the mucosa of 75% of people undergoing surgery for chronic sinusitis.[39]
Diagnosis[edit]
Acute[edit]
Health care providers distinguish bacterial and viral sinusitis by watchful waiting.[1] If a person has had sinusitis for fewer than 10 days without the symptoms becoming worse, then the infection is presumed to be viral.[1] When symptoms last more than 10 days or get worse in that time, then the infection is considered bacterial sinusitis.[40] Imaging by either X-ray, CT or MRI is generally not recommended unless complications develop.[40] Pain caused by sinusitis is sometimes confused for pain caused by pulpitis (toothache) of the maxillary teeth, and vice versa. Classically, the increased pain when tilting the head forwards separates sinusitis from pulpitis.
Chronic[edit]
For sinusitis lasting more than 12 weeks a CT scan is recommended.[40] On a CT scan, acute sinus secretions have a radiodensity of 10 to 25 Hounsfield units (HU), but in a more chronic state they become thickened, with a radiodensity of 30 to 60 HU.[41]
Nasal endoscopy and clinical symptoms are also used to make a positive diagnosis.[28] A tissue sample for histology and cultures can also be collected and tested.[42] Allergic fungal sinusitis (AFS) is often seen in people with asthma and nasal polyps. In rare cases, sinusoscopy may be made.
Nasal endoscopy involves inserting a flexible fiber-optic tube with a light and camera at its tip into the nose to examine the nasal passages and sinuses. This is generally a completely painless (although uncomfortable) procedure which takes between five and ten minutes to complete.
MRI image showing sinusitis. Edema and mucosal thickening appears in both maxillary sinuses.
A computed tomograph showing infection of the ethmoid sinus
Maxillary sinusitis caused by a dental infection associated with periorbital cellulitis
Frontal sinusitis
Treatment[edit]
Treatments[43][44]
Treatment
Indication
Rationale
Time Viral and some bacterial sinusitis Sinusitis is usually caused by a virus which is not affected by antibiotics[43]
Antibiotics Bacterial sinusitis Cases accompanied by extreme pain, skin infection, or which last a long time may be caused by bacteria.[43]
Nasal irrigation Nasal congestion Can provide relief by helping decongest.[43]
Drink liquids Thick phlegm Remaining hydrated loosens mucus.[43]
Antihistamines Concern with allergies Antihistamines do not relieve typical sinusitis or cold symptoms much; this treatment is not needed in most cases.[43]
Nasal spray Desire for temporary relief Tentative evidence that it help symptoms.[5] Does not treat cause. not recommended for more than three days' use.[43]
Recommended treatments for most cases of sinusitis include rest and drinking enough water to thin the mucus.[45] Antibiotics are not recommended for most cases.[45]
Breathing low-temperature steam such as from a hot shower or gargling can relieve symptoms.[45][46] There is tentative evidence for nasal irrigation.[5] Decongestant nasal sprays containing oxymetazoline may provide relief, but these medications should not be used for more than the recommended period. Longer use may cause rebound sinusitis.[47] It is unclear if nasal irrigation, antihistamines, or decongestants work in children with acute sinusitis.[48]
Antibiotics[edit]
Most sinusitis cases are caused by viruses and resolve without antibiotics.[28] However, if symptoms do not resolve within 10 days, amoxicillin is a reasonable antibiotic to use first for treatment[28] with amoxicillin/clavulanate being indicated when the person's symptoms do not improve after 7 days on amoxicillin alone.[40] A 2012 Cochrane review, however, found only a small benefit between 7 and 14 days, and could not recommend the practice when compared to potential complications and risk of developing resistance.[49] Antibiotics are specifically not recommended in those with mild / moderate disease during the first week of infection due to risk of adverse effects, antibiotic resistance, and cost.[50]
Fluoroquinolones, and a newer macrolide antibiotic such as clarithromycin or a tetracycline like doxycycline, are used in those who have severe allergies to penicillins.[51] Because of increasing resistance to amoxicillin the 2012 guideline of the Infectious Diseases Society of America recommends amoxicillin-clavulanate as the initial treatment of choice for bacterial sinusitis.[52] The guidelines also recommend against other commonly used antibiotics, including azithromycin, clarithromycin and trimethoprim/sulfamethoxazole, because of growing drug resistance. The FDA recommends against the use of fluoroquinolones when other options are available due to higher risks of serious side effects.[53]
A short-course (3–7 days) of antibiotics seems to be just as effective as the typical longer-course (10–14 days) of antibiotics for those with clinically diagnosed acute bacterial sinusitis without any other severe disease or complicating factors.[54] The IDSA guideline suggest five to seven days of antibiotics is long enough to treat a bacterial infection without encouraging resistance. The guidelines still recommend children receive antibiotic treatment for ten days to two weeks.[52]
Corticosteroids[edit]
For unconfirmed acute sinusitis, intranasal corticosteroids have not been found to be better than a placebo either alone or in combination with antibiotics.[55] For cases confirmed by radiology or nasal endoscopy, treatment with corticosteroids alone or in combination with antibiotics is supported.[56] The benefit, however, is small.[57]
There is only limited evidence to support short treatment with oral corticosteroids for chronic rhinosinusitis with nasal polyps.[58][59]
Surgery[edit]
For chronic or recurring sinusitis, referral to an otolaryngologist may be indicated, and treatment options may include nasal surgery. Surgery should only be considered for those people who do not benefit with medication.[58][60] It is unclear how benefits of surgery compare to medical treatments in those with nasal polyps as this has been poorly studied.[61]
Maxillary antral washout involves puncturing the sinus and flushing with saline to clear the mucus. A 1996 study of patients with chronic sinusitis found that washout confers no additional benefits over antibiotics alone.[62]
A number of surgical approaches can be used to access the sinuses and these have generally shifted from external/extranasal approaches to intranasal endoscopic ones. The benefit of functional endoscopic sinus surgery (FESS) is its ability to allow for a more targeted approach to the affected sinuses, reducing tissue disruption, and minimizing post-operative complications.[63] The use of drug eluting stents such as propel mometasone furoate implant may help in recovery after surgery.[64]
Another recently developed treatment is balloon sinuplasty. This method, similar to balloon angioplasty used to "unclog" arteries of the heart, utilizes balloons in an attempt to expand the openings of the sinuses in a less invasive manner.
For persistent symptoms and disease in patients who have failed medical and the functional endoscopic approaches, older techniques can be used to address the inflammation of the maxillary sinus, such as the Caldwell-luc antrostomy. This surgery involves an incision in the upper gum, opening in the anterior wall of the antrum, removal of the entire diseased maxillary sinus mucosa and drainage is allowed into inferior or middle meatus by creating a large window in the lateral nasal wall.[65]
Epidemiology[edit]
Sinusitis is a common condition, with between 24 and 31 million cases occurring in the United States annually.[66][67] Chronic sinusitis affects approximately 12.5% of people.[9]
Research[edit]
Based on recent theories on the role that fungus may play in the development of chronic sinusitis, antifungal treatments have been used, on a trial basis. These trials have had mixed results.[28]
See also[edit]
Fungal sinusitis
References[edit]
^ Jump up to: a b c d e f g h i j k l m n o p q r s t u v w x Rosenfeld, RM; Piccirillo, JF; Chandrasekhar, SS; Brook, I; Ashok Kumar, K; Kramper, M; Orlandi, RR; Palmer, JN; Patel, ZM; Peters, A; Walsh, SA; Corrigan, MD (April 2015). "Clinical practice guideline (update): adult sinusitis executive summary". Otolaryngology—head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 152 (4): 598–609. doi:10.1177/0194599815574247. PMID 25833927.
^ Jump up to: a b c d e f g "Sinus Infection (Sinusitis)". cdc.gov. September 30, 2013. Archived from the original on 7 April 2015. Retrieved 6 April 2015.
^ Jump up to: a b c d "What Are the Symptoms of Sinusitis?". April 3, 2012. Archived from the original on 5 April 2015. Retrieved 6 April 2015.
Jump up ^ "Migraines vs. Sinus Headaches". American Migraine Foundation. Retrieved 2017-10-23.
^ Jump up to: a b c d King, D; Mitchell, B; Williams, CP; Spurling, GK (20 April 2015). "Saline nasal irrigation for acute upper respiratory tract infections". The Cochrane database of systematic reviews. 4: CD006821. doi:10.1002/14651858.CD006821.pub3. PMID 25892369.
^ Jump up to: a b Adkinson, N. Franklin (2014). Middleton's allergy : principles and practice (Eight ed.). Philadelphia: Elsevier Saunders. p. 687. ISBN 9780323085939. Archived from the original on 2016-06-03.
Jump up ^ "How Is Sinusitis Treated?". April 3, 2012. Archived from the original on 5 April 2015. Retrieved 6 April 2015.
Jump up ^ "Sinusitis". U.S. National Institute of Allergy and Infectious Diseases. April 3, 2012. Archived from the original on 4 April 2015. Retrieved 6 April 2015.
^ Jump up to: a b c Hamilos DL (October 2011). "Chronic rhinosinusitis: epidemiology and medical management". The Journal of Allergy and Clinical Immunology. 128 (4): 693–707; quiz 708–9. doi:10.1016/j.jaci.2011.08.004. PMID 21890184.
^ Jump up to: a b c Christine Radojicic. "Sinusitis". Disease Management Project. Cleveland Clinic. Archived from the original on November 14, 2012. Retrieved November 26, 2012.
Jump up ^ Pearlman AN, Conley DB (June 2008). "Review of current guidelines related to the diagnosis and treatment of rhinosinusitis". Current Opinion in Otolaryngology & Head and Neck Surgery. 16 (3): 226–30. doi:10.1097/MOO.0b013e3282fdcc9a. PMID 18475076.
^ Jump up to: a b c "Sinusitus Complications". Patient Education. University of Maryland. Archived from the original on 2010-02-22.
Jump up ^ "Sinusitis". herb2000.com. Archived from the original on 2011-05-25. Incidence of acute sinusitis almost always set in following the appearance of a cold for several days at a stretch in the person to the point that all the profuse nasal discharge turns a distinct yellow or a dark green color, or perhaps very thick, and foul-smelling in some cases. [unreliable medical source?]
^ Jump up to: a b c Ferguson, M (May 23, 2014). "Rhinosinusitis in oral medicine and dentistry". Australian dental journal. 59: 289–295. doi:10.1111/adj.12193. PMID 24861778.
Jump up ^ Schreiber CP, Hutchinson S, Webster CJ, Ames M, Richardson MS, Powers C (2004). "Prevalence of migraine in patients with a history of self-reported or physician-diagnosed "sinus" headache". Arch. Intern. Med. 164 (16): 1769–72. doi:10.1001/archinte.164.16.1769. PMID 15364670.
Jump up ^ Mehle ME, Schreiber CP (2005). "Sinus headache, migraine, and the otolaryngologist". Otolaryngol Head Neck Surg. 133 (4): 489–96. doi:10.1016/j.otohns.2005.05.659. PMID 16213917.
Jump up ^ "The International Classification of Headache Disorders: 2nd edition". Cephalalgia. 24 (Suppl 1): 9–160. 2004. doi:10.1111/j.1468-2982.2004.00653.x. PMID 14979299.
^ Jump up to: a b Terézhalmy GT, Huber MA, Jones AC; Noujeim M; Sankar V (2009). Physical evaluation in dental practice. Ames, Iowa: Wiley-Blackwell. p. 27. ISBN 978-0-8138-2131-3. CS1 maint: Multiple names: authors list (link)
Jump up ^ Chandler JR, Langenbrunner DJ, Stevens ER (September 1970). "The pathogenesis of orbital complications in acute sinusitis". Laryngoscope. 80 (9): 1414–28. doi:10.1288/00005537-197009000-00007. PMID 5470225.
Jump up ^ Baker AS (September 1991). "Role of anaerobic bacteria in sinusitis and its complications". Ann Otol Rhinol Laryngol Suppl. 154: 17–22. PMID 1952679.
Jump up ^ Clayman GL, Adams GL, Paugh DR, Koopmann CF (March 1991). "Intracranial complications of paranasal sinusitis: a combined institutional review". Laryngoscope. 101 (3): 234–9. doi:10.1288/00005537-199103000-00003. PMID 2000009.
Jump up ^ Arjmand EM, Lusk RP, Muntz HR (November 1993). "Pediatric sinusitis and subperiosteal orbital abscess formation: diagnosis and treatment". Otolaryngol Head Neck Surg. 109 (5): 886–94. doi:10.1177/019459989310900518. PMID 8247570.
Jump up ^ Harris GJ (March 1994). "Subperiosteal abscess of the orbit. Age as a factor in the bacteriology and response to treatment". Ophthalmology. 101 (3): 585–95. doi:10.1016/S0161-6420(94)31297-8. PMID 8127580.
Jump up ^ Dill SR, Cobbs CG, McDonald CK (February 1995). "Subdural empyema: analysis of 32 cases and review". Clin. Infect. Dis. 20 (2): 372–86. doi:10.1093/clinids/20.2.372. PMID 7742444.
Jump up ^ Stankiewicz JA, Newell DJ, Park AH (August 1993). "Complications of inflammatory diseases of the sinuses". Otolaryngol. Clin. North Am. 26 (4): 639–55. PMID 7692375.
Jump up ^ H. CHELLY, M.JABRI, A. BENHADDOU, F. KADIRI, IA. CHEKKOURY, Y. BENCHAKROUN (15 October 1999). "Le courrier du dentiste" [The maxillary sinusitis of dental origin: From diagnosis to treatment]. Archived from the original on 16 May 2010. CS1 maint: Uses authors parameter (link)
^ Jump up to: a b Hupp JR, Ellis E, Tucker MR (2008). Contemporary oral and maxillofacial surgery (5th ed.). St. Louis, Mo.: Mosby Elsevier. pp. 317–333. ISBN 9780323049030.
^ Jump up to: a b c d e f g h i Leung RS, Katial R (March 2008). "The diagnosis and management of acute and chronic sinusitis". Primary care. 35 (1): 11–24, v–vi. doi:10.1016/j.pop.2007.09.002. PMID 18206715.
Jump up ^ Gwaltney JM, Hendley JO, Phillips CD, Bass CR, Mygind N, Winther B (February 2000). "Nose blowing propels nasal fluid into the paranasal sinuses". Clin. Infect. Dis. 30 (2): 387–91. doi:10.1086/313661. PMID 10671347.
Jump up ^ Mucormycosis at eMedicine
Jump up ^ Gelfand, Jonathan L. "Help for Sinus Pain and Pressure". WebMD.com. Archived from the original on 24 September 2011. Retrieved 2 October 2011.
Jump up ^ Chakrabarti A, Denning DW, Ferguson BJ, Ponikau J, Buzina W, Kita H, Marple B, Panda N, Vlaminck S, Kauffmann-Lacroix C, Das A, Singh P, Taj-Aldeen SJ, Kantarcioglu AS, Handa KK, Gupta A, Thungabathra M, Shivaprakash MR, Bal A, Fothergill A, Radotra BD (September 2009). "Fungal rhinosinusitis: a categorization and definitional schema addressing current controversies". Laryngoscope. 119 (9): 1809–18. doi:10.1002/lary.20520. PMC 2741302  . PMID 19544383.
Jump up ^ Grossman J (1997). "One airway, one disease". Chest. 111 (2 Suppl): 11S–16S. doi:10.1378/chest.111.2_Supplement.11S. PMID 9042022.
Jump up ^ Cruz AA (2005). "The 'united airways' require an holistic approach to management". Allergy. 60 (7): 871–4. doi:10.1111/j.1398-9995.2005.00858.x. PMID 15932375.
Jump up ^ Palmer JN (2005). "Bacterial biofilms: do they play a role in chronic sinusitis?". Otolaryngol. Clin. North Am. 38 (6): 1193–201, viii. doi:10.1016/j.otc.2005.07.004. PMID 16326178.
Jump up ^ Ramadan HH, Sanclement JA, Thomas JG (2005). "Chronic rhinosinusitis and biofilms". Otolaryngol Head Neck Surg. 132 (3): 414–7. doi:10.1016/j.otohns.2004.11.011. PMID 15746854.
Jump up ^ Bendouah Z, Barbeau J, Hamad WA, Desrosiers M (2006). "Biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa is associated with an unfavorable evolution after surgery for chronic sinusitis and nasal polyposis". Otolaryngol Head Neck Surg. 134 (6): 991–6. doi:10.1016/j.otohns.2006.03.001. PMID 16730544.
Jump up ^ Lewis, Kim; Salyers, Abagail A.; Taber, Harry W.; Wax, Richard G., eds. (2002). Bacterial Resistance to Antimicrobials. New York: Marcel Decker. ISBN 978-0-8247-0635-7. Archived from the original on 2014-01-07.
Jump up ^ Sanclement JA, Webster P, Thomas J, Ramadan HH (2005). "Bacterial biofilms in surgical specimens of patients with chronic rhinosinusitis". Laryngoscope. 115 (4): 578–82. doi:10.1097/01.mlg.0000161346.30752.18. PMID 15805862.
^ Jump up to: a b c d Rosenfeld RM, Andes D, Bhattacharyya N, Cheung D, Eisenberg S, Ganiats TG, Gelzer A, Hamilos D, Haydon RC, Hudgins PA, Jones S, Krouse HJ, Lee LH, Mahoney MC, Marple BF, Mitchell CJ, Nathan R, Shiffman RN, Smith TL, Witsell DL (September 2007). "Clinical practice guideline: adult sinusitis". Otolaryngology—head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 137 (3 Suppl): S1–31. doi:10.1016/j.otohns.2007.06.726. PMID 17761281.
Jump up ^ Page 674 Archived 2017-02-16 at the Wayback Machine. in: Paul W. Flint, Bruce H. Haughey, John K. Niparko, Mark A. Richardson, Valerie J. Lund, K. Thomas Robbins, Marci M. Lesperance, J. Regan Thomas (2010). Cummings Otolaryngology – Head and Neck Surgery: Head and Neck Surgery, 3-Volume Set. Elsevier Health Sciences. ISBN 9780323080873. CS1 maint: Multiple names: authors list (link)
Jump up ^ Harrison's Manual of Medicine 16/e
^ Jump up to: a b c d e f g Consumer Reports; American Academy of Family Physicians (April 2012). "Treating sinusitis: Don't rush to antibiotics" (PDF). Choosing wisely: an initiative of the ABIM Foundation. Consumer Reports. Archived (PDF) from the original on June 11, 2012. Retrieved August 17, 2012.
Jump up ^ American Academy of Allergy, Asthma, and Immunology. "Five things physicians and patients should question" (PDF). Choosing Wisely: an initiative of the ABIM Foundation. American Academy of Allergy, Asthma, and Immunology. Archived (PDF) from the original on November 3, 2012. Retrieved August 14, 2012. CS1 maint: Multiple names: authors list (link)
^ Jump up to: a b c Consumer Reports; American Academy of Allergy, Asthma, and Immunology (July 2012), "Treating sinusitis: Don't rush to antibiotics" (PDF), Choosing Wisely: an initiative of the ABIM Foundation, Consumer Reports, archived (PDF) from the original on January 24, 2013, retrieved August 14, 2012 CS1 maint: Multiple names: authors list (link)
Jump up ^ Harvey R, Hannan SA, Badia L, Scadding G (2007). Harvey, Richard, ed. "Nasal saline irrigations for the symptoms of chronic rhinosinusitis". Cochrane Database Syst Rev (3): CD006394. doi:10.1002/14651858.CD006394.pub2. PMID 17636843. CS1 maint: Multiple names: authors list (link)
Jump up ^ Rhinitis medicamentosa at eMedicine
Jump up ^ Shaikh, N; Wald, ER (Oct 27, 2014). "Decongestants, antihistamines and nasal irrigation for acute sinusitis in children". The Cochrane database of systematic reviews. 10: CD007909. doi:10.1002/14651858.CD007909.pub4. PMID 25347280.
Jump up ^ Lemiengre, Marieke B; van Driel, Mieke L; Merenstein, Dan; Young, James; De Sutter, An IM (2012-10-17). Cochrane Database of Systematic Reviews. John Wiley & Sons, Ltd. doi:10.1002/14651858.cd006089.pub4. Archived from the original on 2017-09-04.
Jump up ^ Smith SR, Montgomery LG, Williams JW (Mar 26, 2012). "Treatment of mild to moderate sinusitis". Archives of Internal Medicine. 172 (6): 510–3. doi:10.1001/archinternmed.2012.253. PMID 22450938.
Jump up ^ Karageorgopoulos DE, Giannopoulou KP, Grammatikos AP, Dimopoulos G, Falagas ME (March 2008). "Fluoroquinolones compared with beta-lactam antibiotics for the treatment of acute bacterial sinusitis: a meta-analysis of randomized controlled trials". CMAJ. 178 (7): 845–54. doi:10.1503/cmaj.071157. PMC 2267830  . PMID 18362380.
^ Jump up to: a b Chow AW, Benninger MS, Brook I, Brozek JL, Goldstein EJ, Hicks LA, Pankey GA, Seleznick M, Volturo G, Wald ER, File TM (April 2012). "IDSA clinical practice guideline for acute bacterial rhinosinusitis in children and adults". Clinical Infectious Diseases. 54 (8): e72–e112. doi:10.1093/cid/cir1043. PMID 22438350.
Jump up ^ "Fluoroquinolone Antibacterial Drugs: Drug Safety Communication – FDA Advises Restricting Use for Certain Uncomplicated Infections". FDA. 12 May 2016. Archived from the original on 16 May 2016. Retrieved 16 May 2016.
Jump up ^ Falagas ME, Karageorgopoulos DE, Grammatikos AP, Matthaiou DK (February 2009). "Effectiveness and safety of short vs. long duration of antibiotic therapy for acute bacterial sinusitis: a meta-analysis of randomized trials". Br J Clin Pharmacol. 67 (2): 161–71. doi:10.1111/j.1365-2125.2008.03306.x. PMC 2670373  . PMID 19154447.
Jump up ^ Williamson IG, Rumsby K, Benge S, Moore M, Smith PW, Cross M, Little P (2007). "Antibiotics and Topical Nasal Steroid for Treatment of Acute Maxillary Sinusitis". JAMA. 298 (21): 2487–96. doi:10.1001/jama.298.21.2487. PMID 18056902.
Jump up ^ Zalmanovici Trestioreanu, A; Yaphe, J (2 December 2013). "Intranasal steroids for acute sinusitis". The Cochrane database of systematic reviews. 12: CD005149. doi:10.1002/14651858.CD005149.pub4. PMID 24293353.
Jump up ^ Hayward G, Heneghan C, Perera R, Thompson M (2012). "Intranasal corticosteroids in management of acute sinusitis: a systematic review and meta-analysis". Annals of Family Medicine. 10 (3): 241–9. doi:10.1370/afm.1338. PMC 3354974  . PMID 22585889.
^ Jump up to: a b Fokkens W, Lund V, Mullol J (2007). "European Position Paper on Rhinosinusitis and Nasal Polyps 2007". Rhinol Suppl. 16 (20): 1–136. doi:10.1017/S0959774306000060. PMID 17844873.
Jump up ^ Thomas M, Yawn BP, Price D, Lund V, Mullol J, Fokkens W (June 2008). "EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 – a summary". Prim Care Respir J. 17 (2): 79–89. doi:10.3132/pcrj.2008.00029. PMID 18438594.
Jump up ^ Tichenor WS (2007-04-22). "FAQ — Sinusitis". Archived from the original on 2007-11-01. Retrieved 2007-10-28.
Jump up ^ Rimmer, J; Fokkens, W; Chong, LY; Hopkins, C (1 December 2014). "Surgical versus medical interventions for chronic rhinosinusitis with nasal polyps". The Cochrane database of systematic reviews. 12: CD006991. doi:10.1002/14651858.CD006991.pub2. PMID 25437000.
Jump up ^ Pang YT, Willatt DJ (1996). "Do antral washouts have a place in the current management of chronic sinusitis?". The Journal of laryngology and otology. 110 (10): 926–928. doi:10.1017/s0022215100135376. PMID 8977854.
Jump up ^ Stammberger H (February 1986). "Endoscopic endonasal surgery—concepts in treatment of recurring rhinosinusitis. Part I. Anatomic and pathophysiologic considerations". Otolaryngol Head Neck Surg. 94 (2): 143–7. doi:10.1177/019459988609400202. PMID 3083326.
Jump up ^ Liang J, Lane AP (2013). "Topical Drug Delivery for Chronic Rhinosinusitis". Current Otorhinolaryngology Reports. 1 (1): 51–60. doi:10.1007/s40136-012-0003-4. PMC 3603706  . PMID 23525506.
Jump up ^ Bailey and Love
Jump up ^ Anon JB (April 2010). "Upper respiratory infections". Am. J. Med. 123 (4 Suppl): S16–25. doi:10.1016/j.amjmed.2010.02.003. PMID 20350632.
Jump up ^ Dykewicz MS, Hamilos DL (February 2010). "Rhinitis and sinusitis". The Journal of Allergy and Clinical Immunology. 125 (2 Suppl 2): S103–15. doi:10.1016/j.jaci.2009.12.989. PMID 20176255.
External links[edit]
Classification
V · T · D
ICD-10: J01, J32
ICD-9-CM: 461, 473
MeSH: D012852
DiseasesDB: 12136
External resources
MedlinePlus: 000647
eMedicine: article/232670
Patient UK: Sinusitis

Sinusitis at Curlie (based on DMOZ)
[show]
v
t
e
Diseases of the respiratory system (J, 460–519)
Upper RT
(including URTIs,
common cold)
Head
sinuses
Sinusitis
nose
Rhinitis
Vasomotor rhinitis
Atrophic rhinitis
Hay fever
Nasal polyp
Rhinorrhea
nasal septum
Nasal septum deviation
Nasal septum perforation
Nasal septal hematoma
tonsil
Tonsillitis
Adenoid hypertrophy
Peritonsillar abscess
Neck
pharynx
Pharyngitis
Strep throat
Laryngopharyngeal reflux (LPR)
Retropharyngeal abscess
larynx
Croup
Laryngomalacia
Laryngeal cyst
Laryngitis
Laryngopharyngeal reflux (LPR)
Laryngospasm
vocal folds
Laryngopharyngeal reflux (LPR)
Vocal fold nodule
Vocal fold paresis
Vocal cord dysfunction
epiglottis
Epiglottitis
trachea
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obstructive
acute
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chronic
COPD
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Emphysema)
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unspecified
Bronchitis
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restrictive
(fibrosis)
External agents/
occupational
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Caplan's syndrome
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Klebsiella)
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[show]
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t
e
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preformed:
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synthesized on demand:
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eicosanoids
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Epithelioid cell
Giant cell
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Processes
Traditional
Rubor
Calor
Tumor
Dolor
Functio laesa
Modern
Acute-phase reaction/Fever
Vasodilation
Increased vascular permeability
Exudate
Leukocyte extravasation
Chemotaxis
Specific
locations
Nervous
CNS
Encephalitis
Myelitis
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Arachnoiditis
PNS
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eye
Dacryoadenitis
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chorioretinitis
Retinitis
Chorioretinitis
Blepharitis
Conjunctivitis
Uveitis
ear
Otitis
Labyrinthitis
Mastoiditis
Cardiovascular
Carditis
Endocarditis
Myocarditis
Pericarditis
Vasculitis
Arteritis
Phlebitis
Capillaritis
Respiratory
upper
Sinusitis
Rhinitis
Pharyngitis
Laryngitis
lower
Tracheitis
Bronchitis
Bronchiolitis
Pneumonitis
Pleuritis
Mediastinitis
Digestive
mouth
Stomatitis
Gingivitis
Gingivostomatitis
Glossitis
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Sialadenitis/Parotitis
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Gnathitis
tract
Esophagitis
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Enteritis
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accessory
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soft tissue
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Epicondylitis
Tendinitis
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Osteochondritis: Osteitis/Osteomyelitis
Spondylitis
Periostitis
Chondritis
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female
Oophoritis
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male
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Funisitis
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NDL: 00576408
Retrieved from "https://en.wikipedia.org/w/index.php?title=Sinusitis&oldid=815169297"
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values: التهاب الجيوب – Arabic

values:
https://az.wikipedia.org/wiki/Sinusit
Sinusit – Azerbaijani
az
az
interlanguage-link-target

values:
https://ca.wikipedia.org/wiki/Sinusitis
Sinusitis – Catalan
ca
ca
interlanguage-link-target

values:
https://de.wikipedia.org/wiki/Sinusitis
Sinusitis – German
de
de
interlanguage-link-target

values: ސައިނަސް – Divehi

values: Ιγμορίτιδα – Greek

values:
https://eo.wikipedia.org/wiki/Sinusito
Sinusito – Esperanto
eo
eo
interlanguage-link-target

values:
https://eu.wikipedia.org/wiki/Sinusitis
Sinusitis – Basque
eu
eu
interlanguage-link-target

values: سینوزیت – Persian

values:
https://fr.wikipedia.org/wiki/Sinusite
Sinusite – French
fr
fr
interlanguage-link-target

values: Սինուսիտ – Armenian

values: साइनोसाइटिस – Hindi

values:
https://hr.wikipedia.org/wiki/Sinusitis
Sinusitis – Croatian
hr
hr
interlanguage-link-target

values:
https://id.wikipedia.org/wiki/Sinusitis
Sinusitis – Indonesian
id
id
interlanguage-link-target

values:
https://ia.wikipedia.org/wiki/Sinusitis
Sinusitis – Interlingua
ia
ia
interlanguage-link-target

values:
https://it.wikipedia.org/wiki/Sinusite
Sinusite – Italian
it
it
interlanguage-link-target

values: סינוסיטיס – Hebrew

values: ჰაიმორიტი – Georgian

values: Синусит – Kazakh

values:
https://rw.wikipedia.org/wiki/Sinizite
Sinizite – Kinyarwanda
rw
rw
interlanguage-link-target

values: Гайморит – Kyrgyz

values:
https://ln.wikipedia.org/wiki/Sinusite
Sinusite – Lingala
ln
ln
interlanguage-link-target

values:
https://ms.wikipedia.org/wiki/Resdung
Resdung – Malay
ms
ms
interlanguage-link-target

values: पिनास – Nepali

values: ସାଇନୁସାଇଟିସ – Odia

values: سينوسايټس – Pashto

values:
https://pt.wikipedia.org/wiki/Sinusite
Sinusite – Portuguese
pt
pt
interlanguage-link-target

values: Синусит – Russian

values:
https://sq.wikipedia.org/wiki/Sinuziti
Sinuziti – Albanian
sq
sq
interlanguage-link-target

values: කෝඨරක ප්‍රදාහය – Sinhala

values: Упала синуса – Serbian

values:
https://sh.wikipedia.org/wiki/Sinusitis
Sinusitis – Serbo-Croatian
sh
sh
interlanguage-link-target

values: புரையழற்சி – Tamil

values: Гайморит – Tatar

values: సైనసైటిస్ – Telugu

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