text:
Cranial nerves
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Cranial nerves
Right View of the human brain from below, showing origins of cranial nerves.
Left Juxtaposed skull base with foramina in which many nerves exit the skull.
Cranial nerves as they pass through the skull base to the brain.
Details
Identifiers
Latin
nervus cranialis
(pl: nervi craniales)
MeSH
D003391
TA
A14.2.01.001
A14.2.00.038
FMA
5865
Anatomical terms of neuroanatomy
[edit on Wikidata]
Cranial nerves
CN 0 – Terminal
CN I – Olfactory
CN II – Optic
CN III – Oculomotor
CN IV – Trochlear
CN V – Trigeminal
CN VI – Abducens
CN VII – Facial
CN VIII – Vestibulocochlear
CN IX – Glossopharyngeal
CN X – Vagus
CN XI – Accessory
CN XII – Hypoglossal
Overview
Table
v
t
e
Cranial nerves are the nerves that emerge directly from the brain (including the brainstem), in contrast to spinal nerves (which emerge from segments of the spinal cord).[1] 10 of 12 of the cranial nerves originate in the brainstem. Cranial nerves relay information between the brain and parts of the body, primarily to and from regions of the head and neck.[2]
Spinal nerves emerge sequentially from the spinal cord with the spinal nerve closest to the head (C1) emerging in the space above the first cervical vertebra. The cranial nerves, however, emerge from the central nervous system above this level.[3] Each cranial nerve is paired and is present on both sides. Depending on definition in humans there are twelve or thirteen cranial nerves pairs, which are assigned Roman numerals I–XII, sometimes also including cranial nerve zero. The numbering of the cranial nerves is based on the order in which they emerge from the brain, front to back (brainstem).[1]
The terminal nerves, olfactory nerves (I) and optic nerves (II) emerge from the cerebrum or forebrain, and the remaining ten pairs arise from the brainstem, which is the lower part of the brain.[1]
The cranial nerves are considered components of the peripheral nervous system (PNS),[1] although on a structural level the olfactory, optic and trigeminal nerves are more accurately considered part of the central nervous system (CNS).[4]
Contents
[hide]
1 Anatomy
1.1 Terminology
1.2 Intracranial course
1.2.1 Nuclei
1.2.2 Ganglia
1.2.3 Exiting the skull and extracranial course
2 Function
2.1 Smell (I)
2.2 Vision (II)
2.3 Eye movement (III, IV, VI)
2.4 Trigeminal nerve (V)
2.5 Facial expression (VII)
2.6 Hearing and balance (VIII)
2.7 Oral sensation, taste, and salivation (IX)
2.8 Vagus nerve (X)
2.9 Shoulder elevation and head-turning (XI)
2.10 Tongue movement (XII)
3 Clinical significance
3.1 Examination
3.2 Damage
3.2.1 Compression
3.2.2 Stroke
3.2.3 Inflammation
3.2.4 Other
4 History
5 Other animals
6 See also
7 References
8 External links
Anatomy[edit]
See also: Table of cranial nerves
View of the human brain from below showing the cranial nerves on an autopsy specimen
View from below of the brain and brainstem showing the cranial nerves, numbered from olfactory to hypoglossal after the order in which they emerge
The brainstem, with deeper cranial nerve nuclei and tracts inside the brain-stem shaded red.
Most typically, humans are considered to have twelve pairs of cranial nerves (I–XII). They are: the olfactory nerve (I), the optic nerve (II), oculomotor nerve (III), trochlear nerve (IV), trigeminal nerve (V), abducens nerve (VI), facial nerve (VII), vestibulocochlear nerve (VIII), glossopharyngeal nerve (IX), vagus nerve (X), accessory nerve (XI), and hypoglossal nerve (XII). (There may be a thirteenth cranial nerve, the terminal nerve (nerve O or N), which is very small and may or may not be functional in humans[1][3])
Terminology[edit]
Cranial nerves are generally named according to their structure or function. For example, the olfactory nerve (I) supplies smell, and the facial nerve (VII) supplies motor innervation to the face. Because Latin was the lingua franca (common language) of the study of anatomy when the nerves were first documented, recorded, and discussed, many nerves maintain Latin or Greek names, including the trochlear nerve (IV), named according to its structure, as it supplies a muscle that attaches to a pulley (Greek: trochlea). The trigeminal nerve (V) is named in accordance with its three components (Latin: trigeminus meaning triplets),[5] and the vagus nerve (X) is named for its wandering course (Latin: vagus).[6]
Cranial nerves are numbered based on their rostral-caudal (front-back) position,[1] when viewing the brain. If the brain is carefully removed from the skull the nerves are typically visible in their numeric order, with the exception of the last, CN XII, which appears to emerge rostrally to (above) CN XI.[7]
Cranial nerves have paths within and outside the skull. The paths within the skull are called "intracranial" and the paths outside the skull are called "extracranial". There are many holes in the skull called "foramina" by which the nerves can exit the skull. All cranial nerves are paired, which means that they occur on both the right and left sides of the body. The muscle, skin, or additional function supplied by a nerve on the same side of the body as the side it originates from, is referred to an ipsilateral function. If the function is on the opposite side to the origin of the nerve, this is known as a contralateral function.[8]
Intracranial course[edit]
Intracranial course of cranial nerves is important regarding diagnosis of various intracranial lesions like brain tumors and intracranial arterial aneurysms. Dysfunction of one or more cranial nerves indicates compression or stimulation by some lesion. For example an acoustic schwanoma may initially cause disturbance in hearing but with further growth of tumor it may involve other cranial nerves and the patient may present with pain resembling trigeminal neuralgia when the tumor involves trigeminal nerve or diplopia due to abducent nerve involvement similarly facial palsy with facial nerve compression. These findings along with cerebellar signs will suggest the diagnosis of a CP Angle SOL. A patient presenting with ptosis may have a posterior communicating artery aneurysm compressing the oculomotor nerve during its intracranial course. Facial pain in the distribution of any one or all divisions of trigeminal nerve suggests stimulation of trigeminal nerve roots by a near by vessel.[medical citation needed]
Nuclei[edit]
Main article: Cranial nerve nucleus
The cell bodies of many of the neurons of most of the cranial nerves are contained in one or more nuclei in the brainstem. These nuclei are important relative to cranial nerve dysfunction because damage to these nuclei such as from a stroke or trauma can mimic damage to one or more branches of a cranial nerve. In terms of specific cranial nerve nuclei, the midbrain of the brainstem has the nuclei of the oculomotor nerve (III) and trochlear nerve (IV); the pons has the nuclei of the trigeminal nerve (V), abducens nerve (VI), facial nerve (VII) and vestibulocochlear nerve (VIII); and the medulla has the nuclei of the glossopharyngeal nerve (IX), vagus nerve (X), accessory nerve (XI) and hypoglossal nerve (XII). The fibers of these cranial nerves exit the brainstem from these nuclei.[1]
Ganglia[edit]
Main article: Cranial nerve ganglia
Some of the cranial nerves have sensory or parasympathetic ganglia (collections of cell bodies) of neurons, which are located outside the brain (but can be inside or outside the skull).[1]
The sensory ganglia are directly correspondent to dorsal root ganglia of spinal nerves and are known as cranial sensory ganglia.[7] Sensory ganglia exist for nerves with sensory function: V, VII, VIII, IX, X.[3] There are also parasympathetic ganglia, which are part of the autonomic nervous system for cranial nerves III, VII, IX and X.
The trigeminal ganglia of the trigeminal nerve (V) occupies a space in the dura mater called Trigeminal cave. This ganglion contains the cell bodies of the sensory fibers of the three branches of the trigeminal nerve.
The geniculate ganglion of the facial nerve (VII) is found just after the nerve enters the facial canal; it contains the cell bodies of the sensory fibers of the facial nerve.
Superior and inferior ganglia of the glossopharyngeal nerve (IX), are located just after the nerve passes through the jugular foramen and contain the cell bodies of the sensory fibers of this nerve.
inferior ganglion of vagus nerve (nodose ganglion) is located below the jugular foramen and contains the cell bodies of the sensory fibers of the vagus nerve (X).
Exiting the skull and extracranial course[edit]
Exits of cranial nerves from the skull.[1][9]
Location
Nerve
cribriform plate Olfactory nerve (I)
optic foramen Optic nerve (II)
superior orbital fissure Oculomotor (III)
Trochlear (IV)
Abducens (VI)
Trigeminal V1
(ophthalmic)
Foramen rotundum Trigeminal V2
(maxillary)
Foramen ovale Trigeminal V3
(mandibular)
stylomastoid foramen Facial nerve (VII)
internal auditory canal Vestibulocochlear (VIII)
jugular foramen Glossopharyngeal (IX)
Vagus (X)
Accessory (XI)
hypoglossal canal Hypoglossal (XII)
See also: List of foramina of the human body
After emerging from the brain, the cranial nerves travel within the skull, and some must leave this bony compartment in order to reach their destinations. Often the nerves pass through holes in the skull, called foramina, as they travel to their destinations. Other nerves pass through bony canals, longer pathways enclosed by bone. These foramina and canals may contain more than one cranial nerve, and may also contain blood vessels.[9]
The olfactory nerve (I), actually composed of many small separate nerve fibers, passes through perforations in the cribiform plate part of the ethmoid bone. These fibers terminate in the upper part of the nasal cavity and function to convey impulses containing information about odors to the brain.
The optic nerve (II) passes through the optic foramen in the sphenoid bone as it travels to the eye. It conveys visual information to the brain.
The oculomotor nerve (III), trochlear nerve (IV), abducens nerve (VI) and the ophthalmic branch of the trigeminal nerve (V1) travel through the cavernous sinus into the superior orbital fissure, passing out of the skull into the orbit. These nerves control the small muscles that move the eye and also provide sensory innervation to the eye and orbit.
The maxillary division of the trigeminal nerve (V2) passes through foramen rotundum in the sphenoid bone to supply the skin of the middle of the face.
The mandibular division of the trigeminal nerve (V3) passes through foramen ovale of the sphenoid bone to supply the lower face with sensory innervation. This nerve also sends branches to almost all of the muscles that control chewing.
The facial nerve (VII) and vestibulocochlear nerve (VIII) both enter the internal auditory canal in the temporal bone. The facial nerve then reaches the side of the face by using the stylomastoid foramen, also in the temporal bone. Its fibers then spread out to reach and control all of the muscles of facial expression. The vestibulocochlear nerve reaches the organs that control balance and hearing in the temporal bone, and therefore does not reach the external surface of the skull.
The glossopharyngeal (IX), vagus (X) and accessory nerve (XI) all leave the skull via the jugular foramen to enter the neck. The glossopharyngeal nerve provides innervation to the upper throat and the back of the tongue, the vagus provides innervation to the muscles in the voicebox, and continues downward to supply parasympathetic innervation to the chest and abdomen. The accessory nerve controls the trapezius and sternocleidomastoid muscles in the neck and shoulder.
The hypoglossal nerve (XII) exits the skull using the hypoglossal canal in the occipital bone and reaches the tongue to control almost all of the muscles involved in movements of this organ.[1]
Function[edit]
The cranial nerves provide motor and sensory innervation mainly to the structures within the head and neck. The sensory innervation includes both "general" sensation such as temperature and touch, and "special" innervation such as taste, vision, smell, balance and hearing[1][10]
The vagus nerve (X) provides sensory and autonomic (parasympathetic) motor innervation to structures in the neck and also to most of the organs in the chest and abdomen.[1][3]
Smell (I)[edit]
The olfactory nerve (I) conveys the sense of smell.
Damage to the olfactory nerve (I) can cause an inability to smell (anosmia), a distortion in the sense of smell (parosmia), or a distortion or lack of taste. If there is suspicion of a change in the sense of smell, each nostril is tested with substances of known odors such as coffee or soap. Intensely smelling substances, for example ammonia, may lead to the activation of pain receptors (nociceptors) of the trigeminal nerve that are located in the nasal cavity and this can confound olfactory testing.[1][11]
Vision (II)[edit]
The optic nerve (II) transmits visual information.[3][10]
Damage to the optic nerve (II) affects specific aspects of vision that depend on the location of the lesion. A person may not be able to see objects on their left or right sides (homonymous hemianopsia), or may have difficulty seeing objects on their outer visual fields (bitemporal hemianopsia) if the optic chiasm is involved.[12] Vision may be tested by examining the visual field, or by examining the retina with an ophthalmoscope, using a process known as funduscopy. Visual field testing may be used to pin-point structural lesions in the optic nerve, or further along the visual pathways.[11]
Eye movement (III, IV, VI)[edit]
Various deviations of the eyes due to abnormal function of the targets of the cranial nerves
The oculomotor nerve (III), trochlear nerve (IV) and abducens nerve (VI) coordinate eye movement.
Damage to nerves III, IV, or VI may affect the movement of the eyeball (globe). Both or one eye may be affected; in either case double vision (diplopia) will likely occur because the movements of the eyes are no longer synchronized. Nerves III, IV and VI are tested by observing how the eye follows an object in different directions. This object may be a finger or a pin, and may be moved at different directions to test for pursuit velocity.[11] If the eyes do not work together, the most likely cause is damage to a specific cranial nerve or its nuclei.[11]
Damage to the oculomotor nerve (III) can cause double vision (diplopia) and inability to coordinate the movements of both eyes (strabismus), also eyelid drooping (ptosis) and pupil dilation (mydriasis).[12][12] Lesions may also lead to inability to open the eye due to paralysis of the levator palpebrae muscle. Individuals suffering from a lesion to the oculomotor nerve may compensate by tilting their heads to alleviate symptoms due to paralysis of one or more of the eye muscles it controls.[11]
Damage to the trochlear nerve (IV) can also cause diplopia with the eye adducted and elevated.[12] The result will be an eye which can not move downwards properly (especially downwards when in an inward position). This is due to impairment in the superior oblique muscle, which is innervated by the trochlear nerve.[11]
Damage to the abducens nerve (VI) can also result in diplopia.[12] This is due to impairment in the lateral rectus muscle, which is innervated by the abducens nerve.[11]
Trigeminal nerve (V)[edit]
The trigeminal nerve (V) comprises three distinct parts: The Ophthalmic (V1), the Maxillary (V2), and the Mandibular (V3) nerves. Combined, these nerves provide sensation to the skin of the face and also controls the muscles of mastication (chewing).[1] Conditions affecting the trigeminal nerve (V) include trigeminal neuralgia,[1] cluster headache,[13] and trigeminal zoster.[1] Trigeminal neuralgia occurs later in life, from middle age onwards, most often after age 60, and is a condition typically associated with very strong pain distributed over the area innervated by the maxillary or mandibular nerve divisions of the trigeminal nerve (V2 and V3).[14]
The facial nerve passes through the petrous temporal bone, internal auditory meatus, facial canal, stylomastoid foramen, and then the parotid gland.
Facial expression (VII)[edit]
Lesions of the facial nerve (VII) may manifest as facial palsy. This is where a person is unable to move the muscles on one or both sides of their face. A very common and generally temporary facial palsy is known as Bell's palsy. Bell's Palsy is the result of an idiopathic (unknown cause), unilateral lower motor neuron lesion of the facial nerve and is characterized by an inability to move the ipsilateral muscles of facial expression, including elevation of the eyebrow and furrowing of the forehead. Patients with Bell's palsy often have a drooping mouth on the affected side and often have trouble chewing because the buccinator muscle is affected.[1] Bell's palsy occurs very rarely, affecting around 40,000 Americans annually. There are studies in mice and humans suggesting members of the family Herpesviridae are capable of producing Bell's palsy. Facial paralysis may be caused by other conditions including stroke, and similar conditions to Bell's Palsy are occasionally misdiagnosed as Bell's Palsy.[15] Bell's Palsy is a temporary condition usually lasting 2-6 months, but can have life-changing effects and can reoccur. Strokes typically also affect the seventh cranial nerve by cutting off blood supply to nerves in the brain that signal this nerve and so can present with similar symptoms.
Hearing and balance (VIII)[edit]
The vestibulocochlear nerve (VIII) splits into the vestibular and cochlear nerve. The vestibular part is responsible for innervating the vestibules and semicircular canal of the inner ear; this structure transmits information about balance, and is an important component of the vestibuloocular reflex, which keeps the head stable and allows the eyes to track moving objects. The cochlear nerve transmits information from the cochlea, allowing sound to be heard.[3]
When damaged, the vestibular nerve may give rise to the sensation of spinning and dizziness. Function of the vestibular nerve may be tested by putting cold and warm water in the ears and watching eye movements caloric stimulation.[1][11] Damage to the vestibulocochlear nerve can also present as repetitive and involuntary eye movements (nystagmus), particularly when looking in a horizontal plane.[11] Damage to the cochlear nerve will cause partial or complete deafness in the affected ear.[11]
Oral sensation, taste, and salivation (IX)[edit]
Deviating uvula due to cranial nerve IX lesion
The glossopharyngeal nerve (IX) innervates the stylopharyngeus muscle and provides sensory innervation to the oropharynx and back of the tongue.[1][16] The glossopharyngeal nerve also provides parasympathetic innervation to the parotid gland.[1] Unilateral absence of a gag reflex suggests a lesion of the glossopharyngeal nerve (IX), and perhaps the vagus nerve (X).[17]
Vagus nerve (X)[edit]
Loss of function of the vagus nerve (X) will lead to a loss of parasympathetic innervation to a very large number of structures. Major effects of damage to the vagus nerve may include a rise in blood pressure and heart rate. Isolated dysfunction of only the vagus nerve is rare, but can be diagnosed by a hoarse voice, due to dysfunction of one of its branches, the recurrent laryngeal nerve.[1]
Damage to this nerve may result in difficulties swallowing.[11]
Shoulder elevation and head-turning (XI)[edit]
Winged scapula may occur due to lesion of the spinal accessory.
Damage to the accessory nerve (XI) will lead to ipsilateral weakness in the trapezius muscle. This can be tested by asking the subject to raise their shoulders or shrug, upon which the shoulder blade (scapula) will protrude into a winged position.[1] Additionally, if the nerve is damaged, weakness or an inability to elevate the scapula may be present because the levator scapulae muscle is now solely able to provide this function.[14] Depending on the location of the lesion there may also be weakness present in the sternocleidomastoid muscle, which acts to turn the head so that the face points to the opposite side.[1]
Tongue movement (XII)[edit]
A damaged hypoglossal nerve will result in an inability to stick the tongue out straight.
A case with unilateral hypoglossal nerve injury in branchial cyst surgery. [18]
The hypoglossal nerve (XII) is unique in that it is innervated from the motor cortices of both hemispheres of the brain. Damage to the nerve at lower motor neuron level may lead to fasciculations or atrophy of the muscles of the tongue. The fasciculations of the tongue are sometimes said to look like a "bag of worms". Upper motor neuron damage will not lead to atrophy or fasciculations, but only weakness of the innervated muscles.[11]
When the nerve is damaged, it will lead to weakness of tongue movement on one side. When damaged and extended, the tongue will move towards the weaker or damaged side, as shown in the image.[11]
Clinical significance[edit]
Examination[edit]
Main article: Cranial nerve examination
Physicians, neurologists, and other medical professionals may conduct a cranial nerve examination as part of a neurological examination to examine the functionality of the cranial nerves. This is a highly formalized series of tests that assess the status of each nerve.[19] A cranial nerve exam begins with observation of the patient because some cranial nerve lesions may affect the symmetry of the eyes or face. The visual fields are tested for nerve lesions or nystagmus via an analysis of specific eye movements. The sensation of the face is tested, and patients are asked to perform different facial movements, such as puffing out of the cheeks. Hearing is checked by voice and tuning forks. The position of the patient's uvula is examined because asymmetry in the position could indicate a lesion of the glossopharyngeal nerve. After the ability of the patient to use their shoulder to assess the accessory nerve (XI), and the patient's tongue function is assessed by observing various tongue movements.[1][19]
Damage[edit]
Compression[edit]
Nerves may be compressed because of increased intracranial pressure, a mass effect of an intracerebral haemorrhage, or tumour that presses against the nerves and interferes with the transmission of impulses along the nerve.[20] A loss of functionality of a single cranial nerve may sometimes be the first symptom of an intracranial or skull base cancer.[21]
An increase in intracranial pressure may lead to impairment of the optic nerves (II) due to compression of the surrounding veins and capillaries, causing swelling of the eyeball (papilloedema).[22] A cancer, such as an optic glioma, may also impact the optic nerve (II). A pituitary tumour may compress the optic tracts or the optic chiasm of the optic nerve (II), leading to visual field loss. A pituitary tumour may also extend into the cavernous sinus, compressing the oculuomotor nerve (III), trochlear nerve (IV) and abducens nerve (VI), leading to double-vision and strabismus. These nerves may also be affected by herniation of the temporal lobes of the brain through the falx cerebri.[20]
The cause of trigeminal neuralgia, in which one side of the face is exquisitely painful, is thought to be compression of the nerve by an artery as the nerve emerges from the brain stem.[20] An acoustic neuroma, particularly at the junction between the pons and medulla, may compress the facial nerve (VII) and vestibulocochlear nerve (VIII), leading to hearing and sensory loss on the affected side.[20][23]
Stroke[edit]
Occlusion of blood vessels that supply the nerves or their nuclei, an ischemic stroke, may cause specific signs and symptoms that can localise where the occlusion occurred. A clot in a blood vessel draining the cavernous sinus (cavernous sinus thrombosis) affects the oculomotor (III), trochlear (IV), opthalamic branch of the trigeminal nerve (V1) and the abducens nerve (VI).[23]
Inflammation[edit]
Inflammation resulting from infection may impair the function of any of the cranial nerves. Inflammation of the facial nerve (VII) may result in Bell's palsy.[24]
Multiple sclerosis, an inflammatory process that may produce a loss of the myelin sheathes which surround the cranial nerves, may cause a variety of shifting symptoms affecting multiple cranial nerves.[24]
Other[edit]
Trauma to the skull, disease of bone such as Paget's disease, and injury to nerves during neurosurgery (such as tumor removal) are other possible causes of cranial nerve damage.[23]
History[edit]
The Graeco-Roman anatomist Galen (AD 129–210) named seven pairs of cranial nerves.[25] Much later, in 1664, English anatomist Sir Thomas Willis suggested that there were actually 9 pairs of nerves. Finally, in 1778, German anatomist Samuel Soemmering named the 12 pairs of nerves that are generally accepted today.[25] However, because many of the nerves emerge from the brain stem as rootlets, there is continual debate as to how many nerves there actually are, and how they should be grouped.[25] There is reason to consider both the olfactory (I) and Optic (II) nerves to be brain tracts, rather than cranial nerves.[25] Further, the very small terminal nerve (nerve N or O) exists in humans but may not be functional. In other animals, it appears to be important to sexual receptivity based on perceptions of phermones[1][26]
Other animals[edit]
Dog-fish brain in two projections.
top; ventral bottom; lateral
The accessory nerve (XI) and hypoglossal nerve (XII) cannot be seen, as they are not always present in all vertebrates.
Cranial nerves are also present in other vertebrates. Other amniotes (non-amphibian tetrapods) have cranial nerves similar to those of humans. In anamniotes (fishes and amphibians), the accessory nerve (XI) and hypoglossal nerve (XII) do not exist, with the accessory nerve (XI) being an integral part of the vagus nerve (X); the hypoglossal nerve (XII) is represented by a variable number of spinal nerves emerging from vertebral segments fused into the occiput. These two nerves only became discrete nerves in the ancestors of amniotes (non-amphibian tetrapods).[27]
Diagrammatic view of the cranial nerves of the horse.
Ventral view of the sheep's brain. The exits of the various cranial nerves are marked with red.
See also[edit]
Cranial nerve mnemonics
References[edit]
^ Jump up to: a b c d e f g h i j k l m n o p q r s t u v w x y Vilensky, Joel; Robertson, Wendy; Suarez-Quian, Carlos (2015). The Clinical Anatomy of the Cranial Nerves: The Nerves of "On Olympus Towering Top". Ames, Iowa: Wiley-Blackwell. ISBN 978-1-118-49201-7.
Jump up ^ Standring, Susan; Borley, Neil R. (2008). "Overview of cranial nerves and cranial nerve nuclei". Gray's anatomy: the anatomical basis of clinical practice (40th ed.). [Edinburgh]: Churchill Livingstone/Elsevier. ISBN 978-0-443-06684-9.
^ Jump up to: a b c d e f Kandel, Eric R. (2013). Principles of neural science (5 ed.). Appleton and Lange: McGraw Hill. pp. 1019–1036. ISBN 978-0-07-139011-8.
Jump up ^ Board Review Series – Neuroanatomy, Fourth Edition, Lippincott Williams & Wilkins, Maryland 2008, p. 177. ISBN 978-0-7817-7245-7.
Jump up ^ Harper, Douglas. "Trigeminal Nerve". Online Etymology Dictionary. Retrieved 2 May 2014.
Jump up ^ Davis, Matthew C.; Griessenauer, Christoph J.; Bosmia, Anand N.; Tubbs, R. Shane; Shoja, Mohammadali M. "The naming of the cranial nerves: A historical review". Clinical Anatomy. 27 (1): 14–19. doi:10.1002/ca.22345.
^ Jump up to: a b Mallatt, Elaine N. Marieb, Patricia Brady Wilhelm, Jon (2012). Human anatomy (6th ed. media update. ed.). Boston: Benjamin Cummings. pp. 431–432. ISBN 978-0-321-75327-4.
Jump up ^ Albert, Daniel (2012). Dorland's Illustrated Medical Dictionary (32nd ed.). Philadelphia, PA: Saunders/Elsevier. ISBN 978-1-4160-6257-8.
^ Jump up to: a b Drake, Richard L.; Vogl, Wayne; Tibbitts, Adam W.M. Mitchell; illustrations by Richard; Richardson, Paul (2005). Gray's anatomy for students. Philadelphia: Elsevier/Churchill Livingstone. pp. 800–807. ISBN 978-0-8089-2306-0.
^ Jump up to: a b Mtui, M.J. Turlough FitzGerald, Gregory Gruener, Estomih (2012). Clinical neuroanatomy and neuroscience (6th ed.). [Edinburgh?]: Saunders/Elsevier. p. 198. ISBN 978-0-7020-3738-2.
^ Jump up to: a b c d e f g h i j k l m Kandel, Eric R. (2013). Principles of neural science (5. ed.). Appleton and Lange: McGraw Hill. pp. 1533–1549. ISBN 978-0-07-139011-8.
^ Jump up to: a b c d e Norton, Neil (2007). Netter's head and neck anatomy for dentistry. Philadelphia, Pa.: Saunders Elsevier. ISBN 978-1-929007-88-2. :78
Jump up ^ Nesbitt AD, Goadsby PJ (Apr 11, 2012). "Cluster headache". BMJ (Clinical research ed.) (Review). 344: e2407. doi:10.1136/bmj.e2407. PMID 22496300.
^ Jump up to: a b Fitzgerald, M.J. Turlough FitzGerald, Gregory Gruener, Estomih Mtui (2012). Clinical neuroanatomy and neuroscience (6th ed.). [Edinburgh?]: Saunders/Elsevier. p. 235. ISBN 978-0-7020-3738-2.
Jump up ^ Bell's Palsy Fact Sheet http://bellspalsy.ws/causes-of-facial-palsy/
Jump up ^ Mtui, M.J. Turlough FitzGerald, Gregory Gruener, Estomih (2012). Clinical neuroanatomy and neuroscience (6th ed.). [Edinburgh?]: Saunders/Elsevier. pp. 220–222. ISBN 978-0-7020-3738-2.
Jump up ^ Bickley, Lynn S., Peter G. Szilagyi, and Barbara Bates. Bates' Guide to Physical Examination and History-taking. Philadelphia: Wolters Kluwer Health/Lippincott Williams & Wilkins, 2013. Print.
Jump up ^ Mukherjee, Sudipta; Gowshami, Chandra; Salam, Abdus; Kuddus, Ruhul; Farazi, Mohshin; Baksh, Jahid (2014-01-01). "A case with unilateral hypoglossal nerve injury in branchial cyst surgery". Journal of Brachial Plexus and Peripheral Nerve Injury. 7 (01): 2. doi:10.1186/1749-7221-7-2. PMC 3395866  . PMID 22296879.
^ Jump up to: a b O'Connor, Nicholas J. Talley, Simon (2009). Clinical examination : a systematic guide to physical diagnosis (6th ed.). Chatswood, N.S.W.: Elsevier Australia. pp. 330–352. ISBN 978-0-7295-3905-0.
^ Jump up to: a b c d Britton, the editors Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston ; illustrated by Robert (2010). Davidson's principles and practice of medicine (21st ed.). Edinburgh: Churchill Livingstone/Elsevier. pp. 787, 1215–1217. ISBN 978-0-7020-3085-7.
Jump up ^ Kumar (), Vinay; et al. (2010). Robbins and Cotran pathologic basis of disease (8th ed.). Philadelphia, PA: Saunders/Elsevier. p. 1266. ISBN 978-1-4160-3121-5.
Jump up ^ Britton, the editors Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston ; illustrated by Robert (2010). Davidson's principles and practice of medicine (21st ed.). Edinburgh: Churchill Livingstone/Elsevier. p. 1166. ISBN 978-0-7020-3085-7.
^ Jump up to: a b c Fauci, Anthony S.; Harrison, T. R., eds. (2008). Harrison's principles of internal medicine (17th ed.). New York: McGraw-Hill Medical. pp. 2583–2587. ISBN 978-0-07-147693-5.
^ Jump up to: a b Britton, the editors Nicki R. Colledge, Brian R. Walker, Stuart H. Ralston ; illustrated by Robert (2010). Davidson's principles and practice of medicine (21st ed.). Edinburgh: Churchill Livingstone/Elsevier. pp. 1164–1170, 1192–1193. ISBN 978-0-7020-3085-7.
^ Jump up to: a b c d Davis, Matthew C.; Griessenauer, Christoph J.; Bosmia, Anand N.; Tubbs, R. Shane; Shoja, Mohammadali M. (2014-01-01). "The naming of the cranial nerves: A historical review". Clinical Anatomy. 27 (1): 14–19. doi:10.1002/ca.22345. ISSN 1098-2353.
Jump up ^ Vilensky, JA (January 2014). "The neglected cranial nerve: nervus terminalis (cranial nerve N)". Clin Anat. 27: 46–53. doi:10.1002/ca.22130. PMID 22836597.
Jump up ^ Quiring, Daniel Paul (1950). Functional anatomy of the vertebrates. New York: McGraw-Hill. p. 249.
External links[edit]
Wikimedia Commons has media related to Cranial nerves.
Cranial nerve video (Brainfacts.org)
Cranial Nerves (Yale School of Medicine)
[show]
v
t
e
Nervous system
Central nervous system
Meninges
Spinal cord
Brain
Rhombencephalon
Medulla
Pons
Cerebellum
Midbrain
Forebrain
Diencephalon
Retina
Optic nerve
Cerebrum
Limbic system
Peripheral nervous system
Somatic
Sensory nerve
Motor nerve
Cranial nerve
Spinal nerve
Autonomic
Sympathetic
Parasympathetic
Enteric
[show]
v
t
e
The cranial nerves
terminal
Nuclei
Septal nuclei
Course
no significant branches
olfactory
Nuclei
Anterior olfactory nucleus
Course
olfactory bulb
olfactory tract
optic
Nuclei
Lateral geniculate nucleus
Course
optic chiasm
optic tract
oculomotor
Nuclei
Oculomotor nucleus
Edinger–Westphal nucleus
Branches
superior
parasympathetic root of ciliary ganglion/ciliary ganglion
inferior
trochlear
Nucleus
Branches
no significant branches
trigeminal
Nuclei
PSN
Spinal trigeminal nucleus
MN
TMN
Course
trigeminal ganglion
Branches
ophthalmic
maxillary
mandibular
abducens
Nucleus
Branches
no significant branches
facial
near origin
intermediate nerve
geniculate
inside
facial canal
greater petrosal
pterygopalatine ganglion
nerve to the stapedius
chorda tympani
lingual nerve
submandibular ganglion
at stylomastoid
foramen
posterior auricular
suprahyoid
digastric
stylohyoid
parotid plexus
temporal
zygomatic
buccal
mandibular
cervical
Nuclei
Facial motor nucleus
Solitary nucleus
Superior salivary nucleus
vestibulocochlear
Nuclei
Vestibular nuclei
Cochlear nuclei
cochlear nerve
striae medullares
lateral lemniscus
vestibular
Scarpa's ganglion
glossopharyngeal
before jugular fossa
ganglia
superior
inferior
after jugular fossa
tympanic
tympanic plexus
lesser petrosal
otic ganglion
stylopharyngeal branch
pharyngeal branches
tonsillar branches
lingual branches
carotid sinus
Nuclei
Nucleus ambiguus
Inferior salivatory nucleus
Solitary nucleus
vagus
before jugular fossa
ganglia
superior
inferior
after jugular fossa
meningeal branch
auricular branch
neck
pharyngeal branch
pharyngeal plexus
superior laryngeal
external
internal
recurrent laryngeal (inferior)
superior cervical cardiac
thorax
inferior cardiac
pulmonary
vagal trunks
anterior
posterior
abdomen
celiac
renal
hepatic
anterior gastric
posterior gastric
Nuclei
Nucleus ambiguus
Dorsal nucleus of vagus nerve
Solitary nucleus
accessory
Nuclei
Nucleus ambiguus
Spinal accessory nucleus
cranial
spinal
hypoglossal
Nucleus
Branches
lingual
Authority control
NDL: 00568706
Retrieved from "https://en.wikipedia.org/w/index.php?title=Cranial_nerves&oldid=842728892"
Categories:
Cranial nerves
Hidden categories:
Pages with unresolved properties
Good articles
Articles containing Greek-language text
Articles containing Latin-language text
All articles with unsourced statements
Articles with unsourced statements from May 2018
Navigation menu
Personal tools
Not logged in
Talk
Contributions
Create account
Log in
Namespaces
Article
Talk
Variants
Views
Read
Edit
View history
More
Search
Navigation
Main page
Contents
Featured content
Current events
Random article
Donate to Wikipedia
Wikipedia store
Interaction
Help
About Wikipedia
Community portal
Recent changes
Contact page
Tools
What links here
Related changes
Upload file
Special pages
Permanent link
Page information
Wikidata item
Cite this page
Print/export
Create a book
Download as PDF
Printable version
In other projects
Wikimedia Commons
Languages
العربية
Azərbaycanca
Bân-lâm-gú
Български
Bosanski
Català
Čeština
Dansk
Deutsch
Eesti
Ελληνικά
Español
Esperanto
Euskara
فارسی
Français
Gaeilge
Galego
한국어
Hrvatski
Bahasa Indonesia
Italiano
עברית
Қазақша
Latina
Lietuvių
Magyar
Македонски
Bahasa Melayu
Nederlands
日本語
Norsk
Norsk nynorsk
Polski
Português
Română
Русский
Саха тыла
සිංහල
Simple English
Slovenčina
Slovenščina
Српски / srpski
Srpskohrvatski / српскохрватски
Suomi
Svenska
தமிழ்
తెలుగు
ไทย
Türkçe
Українська
Tiếng Việt
中文
44 more
Edit links
This page was last edited on 24 May 2018, at 08:48.
Text is available under the Creative Commons Attribution-ShareAlike License; additional terms may apply. By using this site, you agree to the Terms of Use and Privacy Policy. Wikipedia® is a registered trademark of the Wikimedia Foundation, Inc., a non-profit organization.
Privacy policy
About Wikipedia
Disclaimers
Contact Wikipedia
Developers
Cookie statement
Mobile view
Enable previews

key: html

type: local

value: div

attrs: id class

values: mw-page-base noprint

values: mw-head-base noprint

value: a

value: img

attrs: alt src width height srcset data-file-width data-file-height

values: This is a good article. Follow the link for more information.

attrs: href title

attrs: class id

attrs: id class lang

values: firstHeading firstHeading en

values: siteSub noprint

values: jump-to-nav mw-jump

value: i

value: th

attrs: colspan style

value: tr

attrs: href class

attrs: href class title

values:
/wiki/Skull_base
mw-redirect
Skull base

value: td

values: padding:0 0.1em 0.4em;text-align:left; padding-left:0.5em; padding-right:0.5em;

values: float:right;clear:right;width:22.0em;margin:0 0 1.0em 1.0em;background:#f9f9f9;border:1px solid #aaa;padding:0.2em;border-spacing:0.4em 0;text-align:center;line-height:1.4em;font-size:88%;margin: 0.5em 0 0.5em 1em; width:auto; border-collapse: collapse;

values:
/wiki/Cranial_nerve_zero
mw-redirect
Cranial nerve zero

values:
/wiki/Latin_language
mw-redirect
Latin language

values: Material near this tag needs references to reliable medical sources. (May 2018)

values: Wikipedia:Identifying reliable sources (medicine)

values:
noprint Inline-Template Template-Fact
white-space:nowrap;

values:
/wiki/Dorsal_root_ganglia
mw-redirect
Dorsal root ganglia

values:
/wiki/Cranial_sensory_ganglia
mw-redirect
Cranial sensory ganglia

values:
/wiki/Trigeminal_ganglia
mw-redirect
Trigeminal ganglia

values: Superior ganglion of glossopharyngeal nerve

values: Inferior ganglion of glossopharyngeal nerve

values: Edit section: Exiting the skull and extracranial course

values:
/wiki/Optic_foramen
mw-redirect
Optic foramen

values:
/wiki/Internal_auditory_canal
mw-redirect
Internal auditory canal

values:
/wiki/Cribiform_plate
mw-redirect
Cribiform plate

values: Edit section: Eye movement (III, IV, VI)

attrs: alt src width height class srcset data-file-width data-file-height

values:
/wiki/Pursuit_velocity
mw-redirect
Pursuit velocity

values:
/wiki/Levator_palpebrae
mw-redirect
Levator palpebrae

values:
/wiki/Petrous_temporal_bone
mw-redirect
Petrous temporal bone

values:
/wiki/Facial_palsy
mw-redirect
Facial palsy

values:
/wiki/Muscles_of_facial_expression
mw-redirect
Muscles of facial expression

values: Edit section: Hearing and balance (VIII)

values:
/wiki/Vestibules_(inner_ear)
mw-redirect
Vestibules (inner ear)

values:
/wiki/Semicircular_canal
mw-redirect
Semicircular canal

values:
/wiki/Vestibuloocular_reflex
mw-redirect
Vestibuloocular reflex

values:
/wiki/Caloric_stimulation
mw-redirect
Caloric stimulation

values: Edit section: Oral sensation, taste, and salivation (IX)

values: Edit section: Shoulder elevation and head-turning (XI)

values:
/wiki/Levator_scapulae
mw-redirect
Levator scapulae

values:
/wiki/Intracerebral_haemorrhage
mw-redirect
Intracerebral haemorrhage

values:
/wiki/Optic_glioma
mw-redirect
Optic glioma

values:
/wiki/Pituitary_tumour
mw-redirect
Pituitary tumour

values:
/wiki/Acoustic_neuroma
mw-redirect
Acoustic neuroma

values:
/wiki/Dogfish_sharks
mw-redirect
Dogfish sharks

values:
nofollow
external text
//doi.org/10.1002%2Fca.22345

values:
nofollow
external text
//doi.org/10.1136%2Fbmj.e2407

values:
/wiki/PubMed_Identifier
mw-redirect
PubMed Identifier

values:
nofollow
external text
//www.ncbi.nlm.nih.gov/pubmed/22496300

values:
nofollow
external text
//doi.org/10.1186%2F1749-7221-7-2

values:
nofollow
external text
//www.ncbi.nlm.nih.gov/pubmed/22296879

values:
nofollow
external text
//www.worldcat.org/issn/1098-2353

values:
nofollow
external text
//doi.org/10.1002%2Fca.22130

values:
nofollow
external text
//www.ncbi.nlm.nih.gov/pubmed/22836597

values: -moz-column-width: 30em; -webkit-column-width: 30em; column-width: 30em; list-style-type: decimal;

values:
nofollow
http://medicine.yale.edu/cranialnerves/
external text

values:
/wiki/Cranial_nerve
mw-redirect
Cranial nerve

values: nowraplinks collapsible autocollapse navbox-inner

values: Parasympathetic root of ciliary ganglion

values: Principal sensory nucleus of trigeminal nerve

values: Mesencephalic nucleus of trigeminal nerve

values:
/wiki/Buccal_branch_of_the_facial_nerve
mw-redirect
Buccal branch of the facial nerve

values: Marginal mandibular branch of facial nerve

values:
/wiki/Superior_salivary_nucleus
mw-redirect
Superior salivary nucleus

values:
/wiki/Cochlear_nuclei
mw-redirect
Cochlear nuclei

values:
/wiki/Striae_medullares
mw-redirect
Striae medullares

values:
/wiki/Scarpa%27s_ganglion
mw-redirect
Scarpa's ganglion

values: Stylopharyngeal branch of glossopharyngeal nerve

values: Pharyngeal branches of glossopharyngeal nerve

values: Tonsillar branches of glossopharyngeal nerve

values: Lingual branches of glossopharyngeal nerve

values: Branch of glossopharyngeal nerve to carotid sinus

values:
/wiki/External_laryngeal_nerve
mw-redirect
External laryngeal nerve

values:
/wiki/Internal_laryngeal_nerve
mw-redirect
Internal laryngeal nerve

values: Superior cervical cardiac branches of vagus nerve

values: Inferior cardiac branches of the vagus nerve

values: Hepatic branches of anterior vagal trunk

values: Anterior gastric branches of anterior vagal trunk

values: Posterior gastric branches of posterior vagal trunk

values: Category:Pages with unresolved properties

values: Category:Articles containing Greek-language text

values: Category:Articles containing Latin-language text

values: Category:All articles with unsourced statements

values: Category:Articles with unsourced statements from May 2018

values: Discussion about edits from this IP address [ctrl-alt-n]

values: A list of edits made from this IP address [ctrl-alt-y]

values: You are encouraged to create an account and log in; however, it is not mandatory

values: You're encouraged to log in; however, it's not mandatory. [ctrl-alt-o]

values:
/wiki/Cranial_nerves
View the content page [ctrl-alt-c]
c

values: Discussion about the content page [ctrl-alt-t]

values: p-namespaces navigation vectorTabs p-namespaces-label

values:
p-variants
navigation
vectorMenu emptyPortlet
p-variants-label

values: Past revisions of this page [ctrl-alt-h]

values: p-views navigation vectorTabs p-views-label

values:
p-cactions
navigation
vectorMenu emptyPortlet
p-cactions-label

values:
mw-wiki-logo
/wiki/Main_Page
Visit the main page

values:
/wiki/Main_Page
Visit the main page [ctrl-alt-z]
z

values: Featured content – the best of Wikipedia

values: Find background information on current events

values:
/wiki/Special:Random
Load a random article [ctrl-alt-x]
x

values: portal navigation p-navigation p-navigation-label

values: Guidance on how to use and edit Wikipedia

values: About the project, what you can do, where to find things

values: A list of recent changes in the wiki [ctrl-alt-r]

values: portal navigation p-wikibase-otherprojects p-wikibase-otherprojects-label

values: أعصاب قحفية – Arabic

values:
interlanguage-link interwiki-az
display: none;

values:
interlanguage-link interwiki-zh-min-nan
display: none;

values: Черепномозъчни нерви – Bulgarian

values:
interlanguage-link interwiki-bg
display: none;

values:
interlanguage-link interwiki-bs
display: none;

values:
interlanguage-link interwiki-ca
display: none;

values:
interlanguage-link interwiki-cs
display: none;

values:
interlanguage-link interwiki-da
display: none;

values:
https://de.wikipedia.org/wiki/Hirnnerv
Hirnnerv – German
de
de
interlanguage-link-target

values:
interlanguage-link interwiki-de
display: none;

values:
interlanguage-link interwiki-et
display: none;

values: Κρανιακά νεύρα – Greek

values:
interlanguage-link interwiki-eo
display: none;

values:
interlanguage-link interwiki-eu
display: none;

values: اعصاب مغزی – Persian

values:
interlanguage-link interwiki-fa
display: none;

values:
interlanguage-link interwiki-fr
display: none;

values:
interlanguage-link interwiki-ga
display: none;

values:
interlanguage-link interwiki-gl
display: none;

values:
interlanguage-link interwiki-ko
display: none;

values:
interlanguage-link interwiki-hr
display: none;

values:
interlanguage-link interwiki-it
display: none;

values: עצבי הגולגולת – Hebrew

values:
interlanguage-link interwiki-he
display: none;

values: Ми жүйкелері – Kazakh

values:
interlanguage-link interwiki-kk
display: none;

values:
interlanguage-link interwiki-lt
display: none;

values:
https://hu.wikipedia.org/wiki/Agyidegek
Agyidegek – Hungarian
hu
hu
interlanguage-link-target

values:
interlanguage-link interwiki-hu
display: none;

values: Мозочни нерви – Macedonian

values:
interlanguage-link interwiki-mk
display: none;

values:
interlanguage-link interwiki-nl
display: none;

values:
interlanguage-link interwiki-ja
display: none;

values:
interlanguage-link interwiki-no
display: none;

values:
interlanguage-link interwiki-nn
display: none;

values:
interlanguage-link interwiki-pl
display: none;

values:
interlanguage-link interwiki-pt
display: none;

values:
interlanguage-link interwiki-ro
display: none;

values: Черепные нервы – Russian

values: Төбө уҥуоҕун ниэрбэлэрэ – Sakha

values:
interlanguage-link interwiki-sah
display: none;

values: කපාල ස්නායු – Sinhala

values:
interlanguage-link interwiki-si
display: none;

values:
interlanguage-link interwiki-simple
display: none;

values:
interlanguage-link interwiki-sk
display: none;

values:
interlanguage-link interwiki-sl
display: none;

values: Мождани живци – Serbian

values:
interlanguage-link interwiki-sr
display: none;

values:
interlanguage-link interwiki-sh
display: none;

values:
https://fi.wikipedia.org/wiki/Aivohermo
Aivohermo – Finnish
fi
fi
interlanguage-link-target

values:
interlanguage-link interwiki-fi
display: none;

values:
interlanguage-link interwiki-sv
display: none;

values: மண்டை நரம்புகள் – Tamil

values:
interlanguage-link interwiki-ta
display: none;

values: కపాల నాడులు – Telugu

values:
interlanguage-link interwiki-te
display: none;

values: ประสาทสมอง – Thai

values:
interlanguage-link interwiki-th
display: none;

values:
interlanguage-link interwiki-tr
display: none;

values: Черепні нерви – Ukrainian

values: interlanguage-link interwiki-uk badge-Q17437796 badge-featuredarticle

values:
interlanguage-link interwiki-vi
display: none;

values: All languages (initial selection from common choices by you and others)

values: mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject page-Cranial_nerves rootpage-Cranial_nerves skin-vector action-view