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Microscope
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This article is about microscopes in general. For light microscopes, see Optical microscope.
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Microscope
Microscope
Uses
Small sample observation
Notable experiments
Discovery of cells
Related items
Optical microscope Electron microscope
A microscope (from the Ancient Greek: μικρός, mikrós, "small" and σκοπεῖν, skopeîn, "to look" or "see") is an instrument used to see objects that are too small to be seen by the naked eye. Microscopy is the science of investigating small objects and structures using such an instrument. Microscopic means invisible to the eye unless aided by a microscope.
There are many types of microscopes, and they may be grouped in different ways. One way is to describe the way the instruments interact with a sample to create images, either by sending a beam of light or electrons to a sample in its optical path, or by scanning across, and a short distance from, the surface of a sample using a probe. The most common microscope (and the first to be invented) is the optical microscope, which uses light to pass through a sample to produce an image. Other major types of microscopes are the fluorescence microscope, the electron microscope (both, the transmission electron microscope and the scanning electron microscope) and the various types of scanning probe microscopes.[1]
Contents
[hide]
1 History
1.1 Rise of modern light microscopes
1.2 Electron microscopes
1.3 Scanning probe microscopes
1.4 Fluorescence microscopes
1.5 Super resolution microscopes
1.6 X-ray microscopes
2 Types
2.1 Optical
2.2 Electron
2.3 Scanning probe
2.4 Other types
3 See also
4 References
5 External links
History
18th-century microscopes from the Musée des Arts et Métiers, Paris.
Further information: Timeline of microscope technology and Optical microscope § History
Although objects resembling lenses date back 4000 years and there are Greek accounts of the optical properties of water-filled spheres (5th century BC) followed by many centuries of writings on optics, the earliest known use of simple microscopes (magnifying glasses) dates back to the widespread use of lenses in eyeglasses in the 13th century.[2][3][4] The earliest known examples of compound microscopes, which combine an objective lens near the specimen with an eyepiece to view a real image, appeared in Europe around 1620.[5] The inventor is unknown although many claims have been made over the years. Several revolve around the spectacle-making centers in the Netherlands including claims it was invented in 1590 by Zacharias Janssen (claim made by his son) and/or Zacharias' father, Hans Martens,[6][7] claims it was invented by their neighbor and rival spectacle maker, Hans Lippershey (who applied for the first telescope patent in 1608),[8] and claims it was invented by expatriate Cornelis Drebbel who was noted to have a version in London in 1619.[9][10] Galileo Galilei (also sometimes cited as compound microscope inventor) seems to have found after 1610 that he could close focus his telescope to view small objects and, after seeing a compound microscope built by Drebbel exhibited in Rome in 1624, built his own improved version.[11][12][13] Giovanni Faber coined the name microscope for the compound microscope Galileo submitted to the Accademia dei Lincei in 1625[14] (Galileo had called it the "occhiolino" or "little eye").
Rise of modern light microscopes
Carl Zeiss binocular compound microscope, 1914
The first detailed account of the microscopic anatomy of organic tissue based on the use of a microscope did not appear until 1644, in Giambattista Odierna's L'occhio della mosca, or The Fly's Eye.[15]
The microscope was still largely a novelty until the 1660s and 1670s when naturalists in Italy, the Netherlands and England began using them to study biology, both organisms and their ultrastructure. Italian scientist Marcello Malpighi, called the father of histology by some historians of biology, began his analysis of biological structures with the lungs. Robert Hooke's Micrographia had a huge impact, largely because of its impressive illustrations. A significant contribution came from Antonie van Leeuwenhoek who achieved up to 300 times magnification using a simple single lens microscope. He sandwiched a very small glass ball lens between the holes in two metal plates riveted together, and with an adjustable-by-screws needle attached to mount the specimen.[16] Then, Van Leeuwenhoek re-discovered red blood cells (after Jan Swammerdam) and spermatozoa, and helped popularise the use of microscopes to view biological ultrastructure. On 9 October 1676, van Leeuwenhoek reported the discovery of micro-organisms.[15]
The performance of a light microscope depends on the quality and correct use of the condensor lens system to focus light on the specimen and the objective lens to capture the light from the specimen and form an image.[5] Early instruments were limited until this principle was fully appreciated and developed from the late 19th to very early 20th century, and until electric lamps were available as light sources. In 1893 August Köhler developed a key principle of sample illumination, Köhler illumination, which is central to achieving the theoretical limits of resolution for the light microscope. This method of sample illumination produces even lighting and overcomes the limited contrast and resolution imposed by early techniques of sample illumination. Further developments in sample illumination came from the discovery of phase contrast by Frits Zernike in 1953, and differential interference contrast illumination by Georges Nomarski in 1955; both of which allow imaging of unstained, transparent samples.
Electron microscopes
See also: electron microscope
Electron microscope constructed by Ernst Ruska in 1933
In the early 20th century a significant alternative to the light microscope was developed, an instrument that uses a beam of electrons rather than light to generate an image. The German physicist, Ernst Ruska, working with electrical engineer Max Knoll, developed the first prototype electron microscope in 1931, a transmission electron microscope (TEM). The transmission electron microscope works on similar principles to an optical microscope but uses electrons in the place of light and electromagnets in the place of glass lenses. Use of electrons, instead of light, allows for much higher resolution.
Development of the transmission electron microscope was quickly followed in 1935 by the development of the scanning electron microscope by Max Knoll.[17] Although TEMs were being used for research before WWII, and became popular afterwards, the SEM was not commercially available until 1965.
Transmission electron microscopes became popular following the Second World War. Ernst Ruska, working at Siemens, developed the first commercial transmission electron microscope and, in the 1950s, major scientific conferences on electron microscopy started being held. In 1965, the first commercial scanning electron microscope was developed by Professor Sir Charles Oatley and his postgraduate student Gary Stewart, and marketed by the Cambridge Instrument Company as the "Stereoscan".
One of the latest discoveries made about using an electron microscope, is the ability to identify a virus.[18] Since this microscope reflects a visible, clear image of small organelles, then in an electron microscope there will no need for reagents to see the virus or harmful cells, resulting with more efficient way for pathogen detection.
Scanning probe microscopes
See also: scanning probe microscope
From 1981 to 1983 Gerd Binnig and Heinrich Rohrer worked at IBM in Zurich, Switzerland to study the quantum tunnelling phenomenon and eventually create a practical instrument, a scanning probe microscope from quantum tunnelling theory that read very small forces exchanged between a probe and the surface of a sample. The probe almost meets the surface so closely that the electrons for an experiment are able to have a continuous flow of electrons, making a current from surface to the probe. The microscope was not initially well received due to the complex nature of the underlying theoretical explanations. In 1984 Jerry Tersoff and D.R. Hamann while at AT&T's Bell Laboratories in Murray Hill, New Jersey began publishing articles that tied the theoretical with the experimental results obtained by the instrument. This was closely followed in 1985 with functioning commercial instruments, and in 1986 with Gerd Binnig, Quate, and Gerber's invention of the atomic force microscope, then Binnig's and Rohrer's Nobel Prize in Physics for the SPM.[19]
Scanning probe microscope types have continued to be developed as the ability to machine ultra fine probes and tips has advanced.
Fluorescence microscopes
See also: fluorescence microscope, immunofluorescence, and confocal microscope
Fluorescence microscope with the filter cube turret above the objective lenses, coupled with a camera.

The most recent developments in light microscope largely centre on the rise of fluorescence microscopy in biology.[citation needed] During the last decades of the 20th century, particularly in the post-genomic era, many techniques for fluorescent staining of cellular structures were developed.[citation needed] The main groups of techniques involve targeted chemical staining of particular cell structures, for example, the chemical compound DAPI to label DNA, use of antibodies conjugated to fluorescent reporters, see immunofluorescence, and fluorescent proteins, such as green fluorescent protein. These techniques use these different fluorophores for analysis of cell structure at a molecular level in both live and fixed samples.
The rise of fluorescence microscopy drove the development of a major modern microscope design, the confocal microscope. The principle was patented in 1957 by Marvin Minsky, although laser technology limited practical application of the technique. It was not until 1978 when Thomas and Christoph Cremer developed the first practical confocal laser scanning microscope and the technique rapidly gained popularity through the 1980s.
Super resolution microscopes
Main articles: Super-resolution microscopy and Microscopy § Sub-diffraction techniques
Much current research (in the early 21st century) on optical microscope techniques is focused on development of superresolution analysis of fluorescently labelled samples. Structured illumination can improve resolution by around two to four times and techniques like stimulated Emission Depletion microscopy are approaching the resolution of electron microscopes. This occurs because the diffraction limit is occurred from light or excitation, which makes the resolution must be doubled to become super saturated.
X-ray microscopes
Main article: X-ray microscope
X-ray microscopes are instruments that use electromagnetic radiation usually in the soft X-ray band to image objects. Technological advances in x-ray lens optics in the early 1970s made the instrument a viable imaging choice.[20] They are often used in tomography (see micro-computed tomography) to produce three dimensional images of objects, including biological materials that have not been chemically fixed. Currently research is being done to improve optics for hard x-rays which have greater penetrating power.[20]
Types
Types of microscopes illustrated by the principles of their beam paths
Evolution of spatial resolution achieved with optical, transmission (TEM) and aberration-corrected electron microscopes (ACTEM).[21]
Microscopes can be separated into several different classes. One grouping is based on what interacts with the sample to generate the image, i.e., light or photons (optical microscopes), electrons (electron microscopes) or a probe (scanning probe microscopes). Alternatively, microscopes can be classed on whether they analyze the sample via a scanning point (confocal optical microscopes, scanning electron microscopes and scanning probe microscopes) or analyze the sample all at once (wide field optical microscope and transmission electron microscopes).
Wide field optical microscopes and transmission electron microscopes both use the theory of lenses (optics for light microscopes and electromagnet lenses for electron microscopes) in order to magnify the image generated by the passage of a wave transmitted through the sample, or reflected by the sample. The waves used are electromagnetic (in optical microscopes) or electron beams (in electron microscopes). Resolution in these microscopes is limited by the wavelength of the radiation used to image the sample, where shorter wavelengths allow for a higher resolution.
Scanning optical and electron microscopes, like the confocal microscope and scanning electron microscope, use lenses to focus a spot of light or electrons onto the sample then analyze the signals generated by the beam interacting with the sample. The point is then scanned over the sample to analyze a rectangular region. Magnification of the image is achieved by displaying the data from scanning a physically small sample area on a relatively large screen. These microscopes have the same resolution limit as wide field optical, probe, and electron microscopes.
Scanning probe microscopes also analyze a single point in the sample and then scan the probe over a rectangular sample region to build up an image. As these microscopes do not use electromagnetic or electron radiation for imaging they are not subject to the same resolution limit as the optical and electron microscopes described above.
Optical
Main article: Optical microscope
The most common type of microscope (and the first invented) is the optical microscope. This is an optical instrument containing one or more lenses producing an enlarged image of a sample placed in the focal plane. Optical microscopes have refractive glass and occasionally of plastic or quartz, to focus light into the eye or another light detector. Mirror-based optical microscopes operate in the same manner. Typical magnification of a light microscope, assuming visible range light, is up to 1250x with a theoretical resolution limit of around 0.250 micrometres or 250 nanometres. This limits the practical magnification limit to ~1500x. Specialized techniques (e.g., scanning confocal microscopy, Vertico SMI) may exceed this magnification but the resolution is diffraction limited. The use of shorter wavelengths of light, such as the ultraviolet, is one way to improve the spatial resolution of the optical microscope, as are devices such as the near-field scanning optical microscope.
Sarfus, a recent optical technique increases the sensitivity of standard optical microscope to a point it becomes possible to directly visualize nanometric films (down to 0.3 nanometre) and isolated nano-objects (down to 2 nm-diameter). The technique is based on the use of non-reflecting substrates for cross-polarized reflected light microscopy.
Ultraviolet light enables the resolution of microscopic features, as well as to image samples that are transparent to the eye. Near infrared light can be used to visualize circuitry embedded in bonded silicon devices, since silicon is transparent in this region of wavelengths.
In fluorescence microscopy, many wavelengths of light, ranging from the ultraviolet to the visible can be used to cause samples to fluoresce to allow viewing by eye or with the use of specifically sensitive cameras.
Phase contrast microscopy is an optical microscopy illumination technique in which small phase shifts in the light passing through a transparent specimen are converted into amplitude or contrast changes in the image. The use of phase contrast does not require staining to view the slide. This microscope technique made it possible to study the cell cycle in live cells.
The traditional optical microscope has more recently evolved into the digital microscope. In addition to, or instead of, directly viewing the object through the eyepieces, a type of sensor similar to those used in a digital camera is used to obtain an image, which is then displayed on a computer monitor. These sensors may use CMOS or charge-coupled device (CCD) technology, depending on the application.
Digital microscopy with very low light levels to avoid damage to vulnerable biological samples is available using sensitive photon-counting digital cameras. It has been demonstrated that a light source providing pairs of entangled photons may minimize the risk of damage to the most light-sensitive samples. In this application of ghost imaging to photon-sparse microscopy, the sample is illuminated with infrared photons, each of which is spatially correlated with an entangled partner in the visible band for efficient imaging by a photon-counting camera.[22]
Electron
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Main article: Electron microscope
Modern transmission electron microscope
The two major types of electron microscopes are transmission electron microscopes (TEMs) and scanning electron microscopes (SEMs). They both have series of electromagnetic and electrostatic lenses to focus a high energy beam of electrons on a sample. In a TEM the electrons pass through the sample, analogous to basic optical microscopy. This requires careful sample preparation, since electrons are scattered strongly by most materials. The SEM has raster coils to scan the surface of bulk objects with a fine electron beam.
Scanning probe
Main article: Scanning probe microscopy
First atomic force microscope
The different types of scanning probe microscopes arise from the many different types of interactions that occur when a small probe of some type is scanned over and interacts with a specimen. These interactions or modes can be recorded or mapped as function of location on the surface to form a characterization map. The three most common types of scanning probe microscopes are atomic force microscopes (AFM), near-field scanning optical microscopes (MSOM or SNOM, scanning near-field optical microscopy), and scanning tunneling microscopes (STM).[23] An atomic force microscope has a fine probe, usually of silicon or silicon nitride, attached to a cantilever; the probe is scanned over the surface of the sample, and the forces that cause an interaction between the probe and the surface of the sample are measured and mapped. A near-field scanning optical microscope is similar to an AFM but its probe consists of a light source in an optical fiber covered with a tip that has usually an aperture for the light to pass through. The microscope can capture either transmitted or reflected light to measure very localized optical properties of the surface, commonly of a biological specimen. Scanning tunneling microscopes have a metal tip with a single apical atom; the tip is attached to a tube through which a current flows.[24] The tip is scanned over the surface of a conductive sample until a tunneling current flows; the current is kept constant by computer movement of the tip and an image is formed by the recorded movements of the tip.[23]
Other types
Scanning acoustic microscopes use sound waves to measure variations in acoustic impedance. Similar to Sonar in principle, they are used for such jobs as detecting defects in the subsurfaces of materials including those found in integrated circuits. On February 4, 2013, Australian engineers built a "quantum microscope" which provides unparalleled precision.[25]
See also
Fluorescence interference contrast microscopy
Laser capture microdissection
Microscope image processing
Microscope slide
Multifocal plane microscopy
Royal Microscopical Society
References
Jump up ^ Characterization and Analysis of Polymers. Hoboken, N.J.: Wiley-Interscience. 2008. ISBN 978-0-470-23300-9.
Jump up ^ Bardell, David (May 2004). "The Invention of the Microscope". Bios. 75 (2): 78–84. JSTOR 4608700.
Jump up ^ The history of the telescope by Henry C. King, Harold Spencer Jones Publisher Courier Dover Publications, 2003 Pgs 25-27 ISBN 0-486-43265-3, ISBN 978-0-486-43265-6
Jump up ^ Atti Della Fondazione Giorgio Ronchi E Contributi Dell'Istituto Nazionale Di Ottica, Volume 30, La Fondazione-1975, page 554
^ Jump up to: a b Murphy, Douglas B.; Davidson, Michael W. (2011). Fundamentals of light microscopy and electronic imaging (2nd ed.). Oxford: Wiley-Blackwell. ISBN 978-0471692140.
Jump up ^ Sir Norman Lockyer. Nature Volume 14.
Jump up ^ Albert Van Helden; Sven Dupré; Rob van Gent (2010). The Origins of the Telescope. Amsterdam University Press. pp. 32–36, 43. ISBN 978-90-6984-615-6.
Jump up ^ "Who Invented the Microscope?". Retrieved 31 March 2017.
Jump up ^ Eric Jorink. Reading the Book of Nature in the Dutch Golden Age, 1575-1715.
Jump up ^ William Rosenthal, Spectacles and Other Vision Aids: A History and Guide to Collecting, Norman Publishing, 1996, page 391 - 392
Jump up ^ Raymond J. Seeger, Men of Physics: Galileo Galilei, His Life and His Works, Elsevier - 2016, page 24
Jump up ^ J. William Rosenthal, Spectacles and Other Vision Aids: A History and Guide to Collecting, Norman Publishing, 1996, page 391
Jump up ^ uoregon.edu, Galileo Galilei (Excerpt from the Encyclopedia Britannica)
Jump up ^ Gould, Stephen Jay (2000). "Chapter 2: The Sharp-Eyed Lynx, Outfoxed by Nature". The Lying Stones of Marrakech: Penultimate Reflections in Natural History. New York, N.Y: Harmony. ISBN 0-224-05044-3.
^ Jump up to: a b Wootton, David (2006). Bad medicine: doctors doing harm since Hippocrates. Oxford [Oxfordshire]: Oxford University Press. p. 110. ISBN 0-19-280355-7. [page needed]
Jump up ^ Liz Logan (27 April 2016). "Early Microscopes Revealed a New World of Tiny Living Things". Smithsonian.com. Retrieved 3 June 2016.
Jump up ^ Knoll, Max (1935). "Aufladepotentiel und Sekundäremission elektronenbestrahlter Körper". Zeitschrift für technische Physik. 16: 467–475.
Jump up ^ Goldsmith, Cynthia S.; Miller, Sara E. (2009-10-01). "Modern Uses of Electron Microscopy for Detection of Viruses". Clinical Microbiology Reviews. 22 (4): 552–563. doi:10.1128/cmr.00027-09. ISSN 0893-8512. PMID 19822888.
Jump up ^ Morita, Seizo (2007). Roadmap of Scanning Probe Microscopy. Berlin, Heidelberg: Springer-Verlag Berlin Heidelberg. ISBN 978-3540343158.
^ Jump up to: a b Erko, A. (2008). Modern developments in X-ray and neutron optics. Berlin: Springer. ISBN 978-3-540-74561-7.
Jump up ^ Pennycook, S.J.; Varela, M.; Hetherington, C.J.D.; Kirkland, A.I. (2011). "Materials Advances through Aberration-Corrected Electron Microscopy" (PDF). MRS Bulletin. 31: 36. doi:10.1557/mrs2006.4.
Jump up ^ Aspden, Reuben S.; Gemmell, Nathan R.; Morris, Peter A.; Tasca, Daniel S.; Mertens, Lena; Tanner, Michael G.; Kirkwood, Robert A.; Ruggeri, Alessandro; Tosi, Alberto; Boyd, Robert W.; Buller, Gerald S.; Hadfield, Robert H.; Padgett, Miles J. (2015). "Photon-sparse microscopy: visible light imaging using infrared illumination". Optica. 2 (12): 1049. doi:10.1364/OPTICA.2.001049. ISSN 2334-2536.
^ Jump up to: a b Bhushan, Bharat, ed. (2010). Springer handbook of nanotechnology (3rd rev. & extended ed.). Berlin: Springer. p. 620. ISBN 978-3-642-02525-9.
Jump up ^ Sakurai, T.; Watanabe, Y., eds. (2000). Advances in scanning probe microscopy. Berlin: Springer. ISBN 978-3-642-56949-4.
Jump up ^ "Quantum Microscope for Living Biology". Science Daily. 4 February 2013. Retrieved 5 February 2013.
External links
Wikimedia Commons has media related to Microscopes.
Microscopy laboratory in: A Study Guide to the Science of Botany at Wikibooks
Milestones in Light Microscopy, Nature Publishing
FAQ on Optical Microscopes
Nikon MicroscopyU, tutorials from Nikon
Molecular Expressions : Exploring the World of Optics and Microscopy, Florida State University.
Microscopes made from bamboo at Nature.com
Audio microscope glossary
Billings Microscope Collection Catalogue, National Museum of Health and Medicine.
Study and Read at the Royal Microscopical Society
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text:
Muscle tissue
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Muscle tissue
The body contains three types of muscle tissue: (a) skeletal muscle, (b) smooth muscle, and (c) cardiac muscle. (Same magnification)
A schematic diagram of the different types of muscle cells (same order as above).
Identifiers
MeSH
D009132
Anatomical terminology
[edit on Wikidata]
Muscle tissue is a soft tissue that composes muscles in animal bodies, and gives rise to muscles' ability to contract. This is opposed to other components or tissues in muscle such as tendons or perimysium. It is formed during embryonic development through a process known as myogenesis.[1]
Muscle tissue varies with function and location in the body. In mammals the three types are: skeletal or striated muscle; smooth or non-striated muscle; and cardiac muscle, which is sometimes known as semi-striated. Smooth and cardiac muscle contracts involuntarily, without conscious intervention. These muscle types may be activated both through interaction of the central nervous system as well as by receiving innervation from peripheral plexus or endocrine (hormonal) activation. Striated or skeletal muscle only contracts voluntarily, upon influence of the central nervous system. Reflexes are a form of non-conscious activation of skeletal muscles, but nonetheless arise through activation of the central nervous system, albeit not engaging cortical structures until after the contraction has occurred.[1]
The different muscle types vary in their response to neurotransmitters and endocrine substances such as acetylcholine, noradrenaline, adrenaline, nitric oxide and among others depending on muscle type and the exact location of the muscle.[1]
Sub-categorization of muscle tissue is also possible, depending on among other things the content of myoglobin, mitochondria, myosin ATPase etc.
Contents
[hide]
1 Structure
1.1 Comparison of types
1.2 Skeletal muscle
1.3 Smooth muscle
1.4 Cardiac muscle
2 Function
2.1 Skeletal muscle
2.2 Smooth muscle
2.3 Cardiac muscle
3 See also
4 References
Structure[edit]
Muscle cells (myocytes) are elongated cells ranging from several millimetres to about 10 centimetres in length and from 10 to 100 micrometres in width.[2] These cells are joined together in tissues that may be either striated or smooth, depending on the presence or absence, respectively, of organized, regularly repeated arrangements of myofibrillar contractile proteins called myofilaments. Striated muscle is further classified as either skeletal or cardiac muscle.[3] Striated muscle is typically subject to conscious control, while smooth muscle is not. Thus, muscle tissue can be described as being one of three different types:
Skeletal muscle, striated in structure and under voluntary control, is anchored by tendons (or by aponeuroses at a few places) to bone and is used to effect skeletal movement such as locomotion and to maintain posture. (Though postural control is generally maintained as an unconscious reflex—see proprioception—the muscles responsible also react to conscious control like non-postural muscles.) An average adult male is made up of 42% of skeletal muscle and an average adult female is made up of 36% (as a percentage of body mass).[4] It also has striations unlike smooth muscle.
Smooth muscle, neither striated in structure nor under voluntary control, is found within the walls of organs and structures such as the esophagus, stomach, intestines, bronchi, uterus, urethra, bladder, blood vessels, and the arrector pili in the skin (in which it controls erection of body hair).
In vertebrates, there is a third muscle tissue recognized:
Cardiac muscle (myocardium), found only in the heart, is a striated muscle similar in structure to skeletal muscle but not subject to voluntary control.
Cardiac and skeletal muscles are "striated" in that they contain sarcomeres and are packed into highly regular arrangements of bundles; smooth muscle has neither. While skeletal muscles are arranged in regular, parallel bundles, cardiac muscle connects at branching, irregular angles (called intercalated discs). Striated muscle contracts and relaxes in short, intense bursts, whereas smooth muscle sustains longer or even near-permanent contractions.
Comparison of types[edit]
smooth muscle cardiac muscle skeletal muscle
Anatomy
Neuromuscular junction none none present
Fibers fusiform, short (<0.4 mm) branching cylindrical, long (<15 cm)
Mitochondria few numerous many to few (by type)
Nuclei 1 1 >1
Sarcomeres none present, max. length 2.6 µm present, max. length 3.7 µm
Syncytium none (independent cells) none (but functional as such) present
Sarcoplasmic reticulum little elaborated moderately elaborated highly elaborated
ATPase little moderate abundant
Physiology
Self-regulation spontaneous action (slow) yes (rapid) none (requires nerve stimulus)
Response to stimulus unresponsive "all-or-nothing" "all-or-nothing"
Action potential yes yes yes
Workspace Force/length curve is variable the increase in the force/length curve at the peak of the force/length curve
Response to stimulus
Skeletal muscle[edit]
Main article: Skeletal muscle
Striated skeletal muscle cells in microscopic view. The myofibers are the straight vertical bands; the horizontal striations (lighter and darker bands) that are visible result from differences in composition and density along the fibrils within the cells. The cigar-like dark patches beside the myofibers are muscle-cell nuclei.
Skeletal muscle is further divided into several subtypes:
Type I, slow oxidative, slow twitch, or "red" muscle is dense with capillaries and is rich in mitochondria and myoglobin, giving the muscle tissue its characteristic red color. It can carry more oxygen and sustain aerobic activity.
Type I muscle fiber are sometimes broken down into Type I and Type Ic categories, as a result of recent research.[5]
Type II, fast twitch muscle, has three major kinds that are, in order of increasing contractile speed:[6]
Type IIa, which, like slow muscle, is aerobic, rich in mitochondria and capillaries and appears red when deoxygenated.
Type IIx (also known as type IId), which is less dense in mitochondria and myoglobin. This is the fastest muscle type in humans. It can contract more quickly and with a greater amount of force than oxidative muscle, but can sustain only short, anaerobic bursts of activity before muscle contraction becomes painful (often incorrectly attributed to a build-up of lactic acid). N.B. in some books and articles this muscle in humans was, confusingly, called type IIB.[7]
Type IIb, which is anaerobic, glycolytic, "white" muscle that is even less dense in mitochondria and myoglobin. In small animals like rodents this is the major fast muscle type, explaining the pale color of their flesh.
Smooth muscle[edit]
Main article: Smooth muscle tissue
Smooth muscle is an involuntary non-striated muscle. It is divided into two subgroups: the single-unit (unitary) and multiunit smooth muscle. Within single-unit cells, the whole bundle or sheet contracts as a syncytium (i.e. a multinucleate mass of cytoplasm that is not separated into cells). Multiunit smooth muscle tissues innervate individual cells; as such, they allow for fine control and gradual responses, much like motor unit recruitment in skeletal muscle.
Smooth muscle is found within the walls of blood vessels (such smooth muscle specifically being termed vascular smooth muscle) such as in the tunica media layer of large (aorta) and small arteries, arterioles and veins. Smooth muscle is also found in lymphatic vessels, the urinary bladder, uterus (termed uterine smooth muscle), male and female reproductive tracts, gastrointestinal tract, respiratory tract, arrector pili of skin, the ciliary muscle, and iris of the eye. The structure and function is basically the same in smooth muscle cells in different organs, but the inducing stimuli differ substantially, in order to perform individual effects in the body at individual times. In addition, the glomeruli of the kidneys contain smooth muscle-like cells called mesangial cells.
Cardiac muscle[edit]
Main article: Cardiac muscle
Cardiac muscle is involuntary, striated muscle that is found in the walls and histological foundation of the heart, specifically the myocardium. Cardiac muscle is one of three major types of muscle, the others being skeletal and smooth muscle. These three types of muscle all form in the process of myogenesis. The cells that constitute cardiac muscle, called cardiomyocytes or myocardiocytes, predominantly contain only one nucleus, although populations with two to four nuclei do exist.[8][9][page needed] The myocardium is the muscle tissue of the heart, and forms a thick middle layer between the outer epicardium layer and the inner endocardium layer.
Coordinated contractions of cardiac muscle cells in the heart propel blood out of the atria and ventricles to the blood vessels of the left/body/systemic and right/lungs/pulmonary circulatory systems. This complex mechanism illustrates systole of the heart.
Cardiac muscle cells, unlike most other tissues in the body, rely on an available blood and electrical supply to deliver oxygen and nutrients and remove waste products such as carbon dioxide. The coronary arteries help fulfill this function.
Function[edit]
This section needs expansion. You can help by adding to it. (March 2014)
Skeletal muscle[edit]
1.They carry out movements of the body.
2.They support the body.
3.They maintain the posture of the body.
Smooth muscle[edit]
It is responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the bladder.
Cardiac muscle[edit]
Cardiac muscle is the muscle of the heart. It is self-contracting, autonomically regulated and must continue to contract in rhythmic fashion for the whole life of the organism. Hence it has special features.
See also[edit]
Myocyte
References[edit]
^ Jump up to: a b c "Muscle Tissue TheVisualMD.com". www.thevisualmd.com. Retrieved 2015-12-30.
Jump up ^ Hugh Potter, Summary of muscle tissue Archived 2014-10-21 at the Wayback Machine.
Jump up ^ Pratt, Rebecca. "Muscle Tissue". AnatomyOne. Amirsys, Inc. Archived from the original on 2 February 2017. Retrieved 26 October 2012.
Jump up ^ Marieb, Elaine; Hoehn, Katja (2007). Human Anatomy & Physiology (7th ed.). Pearson Benjamin Cummings. p. 317. ISBN 0-8053-5387-9.
Jump up ^ McCloud, Aaron (30 November 2011). "Build Fast Twitch Muscle Fibers". Complete Strength Training. Retrieved 30 November 2011.
Jump up ^ Larsson, L; Edström, L; Lindegren, B; Gorza, L; Schiaffino, S (July 1991). "MHC composition and enzyme-histochemical and physiological properties of a novel fast-twitch motor unit type". The American Journal of Physiology. 261 (1 pt 1): C93–101. PMID 1858863. Retrieved 2006-06-11.
Jump up ^ Smerdu, V; Karsch-Mizrachi, I; Campione, M; Leinwand, L; Schiaffino, S (December 1994). "Type IIx myosin heavy chain transcripts are expressed in type IIb fibers of human skeletal muscle". The American Journal of Physiology. 267 (6 pt 1): C1723–1728. PMID 7545970. Retrieved 2006-06-11. Note: Access to full text requires subscription; abstract freely available
Jump up ^ Olivetti G, Cigola E, Maestri R, et al. (July 1996). "Aging, cardiac hypertrophy and ischemic cardiomyopathy do not affect the proportion of mononucleated and multinucleated myocytes in the human heart". Journal of Molecular and Cellular Cardiology. 28 (7): 1463–77. doi:10.1006/jmcc.1996.0137. PMID 8841934.
Jump up ^ Pollard, Thomas D. and Earnshaw, William. C., "Cell Biology". Philadelphia: Saunders. 2007.
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Skeletal striated muscle

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Plexus (neuroanatomy)

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Smooth muscle

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Erectores pilorum

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Smooth endoplasmic reticulum

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Slow-twitch muscle

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Aerobic metabolism

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Fast-twitch muscle

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Fermentation (biochemistry)

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Blood vessels

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Uterine smooth muscle

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