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Johnson & Johnson
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Not to be confused with S. C. Johnson & Son.
Johnson & Johnson
J&J headquarters at One Johnson & Johnson Plaza in New Brunswick, New Jersey
Type
Public
Traded as
NYSE: JNJ
DJIA Component
S&P 100 Component
S&P 500 Component
ISIN
US4781601046
Industry
Medical equipment
Pharmaceutical
Founded
January 1886; 131 years ago (1886-01)
New Brunswick, New Jersey, U.S.
Founders
Robert Wood Johnson I
James Wood Johnson
Edward Mead Johnson
Headquarters
One Johnson & Johnson Plaza, New Brunswick, New Jersey, U.S.
Area served
Worldwide
Key people
Alex Gorsky (Chairman and CEO)
Products
See list of Johnson & Johnson products
Revenue
US$71.89 billion (2016)[1]
Operating income
US$19.80 billion (2016)[1]
Net income
US$16.54 billion (2016)[1]
Total assets
US$133.41 billion (2016)[1]
Total equity
US$71.15 billion (2016)[1]
Number of employees
127,100 (2016)[1]
Subsidiaries
McNeil Consumer Healthcare
Vistakon[2]
Neutrogena
DePuy
Website
www.jnj.com
Johnson & Johnson is an American multinational medical devices, pharmaceutical and consumer packaged goods manufacturing company founded in 1886. Its common stock is a component of the Dow Jones Industrial Average and the company is listed among the Fortune 500.
Johnson & Johnson is headquartered in New Brunswick, New Jersey, the consumer division being located in Skillman, New Jersey. The corporation includes some 250 subsidiary companies with operations in 60 countries and products sold in over 175 countries. Johnson & Johnson had worldwide sales of $70.1 billion during calendar year 2015.[3]
Johnson & Johnson's brands include numerous household names of medications and first aid supplies. Among its well-known consumer products are the Band-Aid Brand line of bandages, Tylenol medications, Johnson's baby products, Neutrogena skin and beauty products, Clean & Clear facial wash and Acuvue contact lenses.
Contents
[hide]
1 History
1.1 Foundation and early history
1.2 1959: McNeil Consumer Healthcare
1.3 1959: Cilag
1.4 1961: Janssen Pharmaceuticals
1.5 1998: DePuy
1.6 1999: Janssen Biotech, Inc.
1.7 Ethicon, Inc
1.7.1 Ethicon Endo-Surgery, Inc.
1.8 Actelion
1.9 Johnson & Johnson Vision Care, Inc
1.10 2010 onwards
1.11 Structure
2 Corporate governance
3 JNJ Headquarters and the New Brunswick gentrification
3.1 Chairmen
4 Products
4.1 Pharmaceuticals
4.2 Medical devices
4.3 Consumer health
5 Environmental record
6 Recalls and litigation
6.1 1982 Chicago Tylenol murders
6.2 2010 children's product recall
6.3 2010 hip-replacement recall
6.4 2010 Tylenol recall
6.5 Shareholders lawsuit
6.6 Illegal marketing of Risperdal
6.7 Foreign bribery
6.8 Consumer Fraud Settlements
6.9 Use of the Red Cross symbol
6.10 Boston Scientific lawsuits
6.11 Patent-infringement case against Abbott
6.12 Vaginal mesh implants
6.13 Baby powder
7 See also
8 References
9 External links
History[edit]
Johnson & Johnson operates over 250 companies in what is termed "the Johnson & Johnson family of companies".[4] The company operates in three broad divisions; Consumer Healthcare, Medical Devices and Pharmaceuticals.
Johnson & Johnson Family of Companies
Consumer Healthcare[5]
Medical Devices[6]
Pharmaceuticals[7]
Baby Care
Skin & Hair Care
Wound Care and Topicals
Oral Health Care
Women’s Health
McNeil Consumer Healthcare
Over-The-Counter Medicines
Nutritionals Advanced Sterilization Products
Animas Corporation
Biosense Webster
DePuy Synthes
Ethicon, Inc.
Janssen Diagnostics BVBA
Johnson & Johnson Vision Care, Inc.
LifeScan, Inc.
Mentor Janssen
Janssen R&D LLC
Janssen Healthcare Innovation
Janssen Pharmaceuticals Inc
Janssen Diagnostics
Janssen Therapeutics
Janssen Scientific Affairs
McNeil-PPC, Inc
Foundation and early history[edit]
Robert Wood Johnson
Inspired by a speech by antiseptic advocate Joseph Lister, Robert Wood Johnson joined his brothers James Wood Johnson and Edward Mead Johnson to create a line of ready-to-use surgical dressings in 1885. The company produced its first products in 1886 and incorporated in 1887.
Robert Wood Johnson served as the first president of the company. He worked to improve sanitation practices in the nineteenth century, and lent his name to the Robert Wood Johnson University Hospital in New Brunswick, New Jersey. Upon his death in 1910, he was succeeded in the presidency by his brother James Wood Johnson until 1932, and then by his son, Robert Wood Johnson II.
Robert Wood Johnson's granddaughter, Mary Lea Johnson Richards, was the first baby to appear on a Johnson & Johnson baby powder label.[8][9][10] His great-grandson, Jamie Johnson, made a documentary called Born Rich about the experience of growing up as the heir to one of the world's greatest fortunes.
1959: McNeil Consumer Healthcare[edit]
McNeil Consumer Healthcare was founded on March 16, 1879 by 23-year-old Robert McNeil. In 1904, one of McNeil's sons, Robert Lincoln McNeil, became part of the company and together they created McNeil Laboratories in 1933. The company focused on direct marketing of prescription drugs to hospitals, pharmacists, and doctors. Development of acetaminophen began under the leadership of Robert L. McNeil, Jr., who later served as the firm's chairman.[11] In 1959, Johnson & Johnson acquired McNeil Laboratories and a year later the company was able to sell Tylenol for the first time ever, without a prescription. In 1977, two subsidiary companies were created; McNeil medicals products and McNeil Consumer Products Company (also known as McNeil Consumer Healthcare). The focus of McNeil medicals products is to market prescription drugs. In 1993 McNeil medicals products merged with the Ortho Pharmaceutical to form Ortho-McNeil Pharmaceutical. In 2001 McNeil Consumer Healthcare changed its name to McNeil Consumer & Specialty medicals products. However, it was later changed to "McNeil Consumer Healthcare". The company markets over-the-counter and prescription medicals products including complete lines of Tylenol and Motrin IB (ibuprofen) products for adults and children.
1959: Cilag[edit]
In 1933, Swiss chemist Bernhard Joos set up a small research laboratory in Schaffhausen, Switzerland. This set the basis for the founding of Chemische Industrie-Labor AG (Chemical Industry Laboratory AG or Cilag) on 12 May 1936. In 1959, Cilag joined the Johnson & Johnson family of companies. In the early nineties, the marketing organizations of Cilag and Janssen Pharmaceutica were joined to form Janssen-Cilag. The non-marketing activities of both companies still operate under their original name. Cilag continues to have operations under the Cilag name in Switzerland, ranging from research and development through manufacturing and international services. In August 2014, Cilag acquired Covagen a biopharmaceutical company which specialises in the development of multi-specific protein based therapeutics. As part of the acquisition Cilag wll gain access to Covagen’s lead drug candidate, COVA 322, a bi-specific anti-tumor necrosis factor (TNF)-alpha/anti-interleukin (IL)-17A FynomAb, is in a Phase Ib study for psoriasis.[12]
1961: Janssen Pharmaceuticals[edit]
Janssen Pharmaceuticals can be traced back to 1933. In 1933, Constant Janssen, the father of Paul Janssen, acquired the right to distribute the pharmaceutical products of Richter, a Hungarian pharmaceutical company, for Belgium, the Netherlands and Belgian Congo. On 23 October 1934, he founded the N.V. Produkten Richter in Turnhout. After the Second World War, the name for the company products was changed to Eupharma, although the company name Richter would remain until 1956.[13]
Paul Janssen founded his own research laboratory in 1953 on the third floor of the building in the Statiestraat, still within the Richter-Eurpharma company of his father. On 5 April 1956, the name of the company was changed to NV Laboratoria Pharmaceutica C. Janssen (named after Constant Janssen). On 2 May 1958, the research department in Beerse became a separate legal entity, the N.V. Research Laboratorium C. Janssen. On 24 October 1961, the company was acquired by the American corporation Johnson & Johnson. On 10 February 1964, the name was changed to Janssen Pharmaceutica N.V. Between 1990 and 2004, Janssen Pharmaceuticals expanded worldwide, with the company growing in size to approximately 28000 employees worldwide. In 1999, clinical research and non-clinical development become a global organization within Johnson & Johnson. In 2001, part of the research activities was transferred to the United States with the reorganization of research activities in the Johnson & Johnson Pharmaceutical Research and Development organization. The research activities of the Janssen Research Foundation and the R.W. Johnson Pharmaceutical Research Institute were merged into the new global research organization. On 27 October 2004, the Paul Janssen Research Center, for discovery research, was inaugurated.
In August 2013, the company acquired Aragon Pharmaceuticals, Inc.. In November 2014, the company acquired Alios BioPharma, Inc. for $1.75 billion. As a result of the purchase, Alios was incorporated into the infectious diseases therapeutic area of the Janssen Pharmaceutical Companies of Johnson & Johnson.[14] In March 2015, Janssen licensed Tipofarnib (a farnesyl transferase inhibitor) to Kura Oncology who will assume sole responsibility for developing and commercialising the anti-cancer drug.[15] Later in the same month the company announced that Galapagos Pharma and regained the rights to the anti-inflammatory drug candidate GLPG1690 as well as two other compounds including GLPG1205 (a first-in-class inhibitor of GPR84).[16] Finally, in March, the company acquired XO1 Limited [17] In November 2015, the company acquired Novira Therapeutics, Inc., gaining the lead candidate, NVR 3-778.[18]
1998: DePuy[edit]
DePuy was acquired by J&J in 1998, rolling it into the Johnson & Johnson Medical Devices group. On June 14, 2012, Johnson and Johnson completed the acquisition of Synthes for $19.7 billion,[19] which was then integrated with the DePuy franchise to establish the DePuy Synthes Companies of Johnson & Johnson which includes; Codman & Shurteff, Inc., DePuy Mitek, Inc., DePuy Orthopaedics, Inc. and DePuy Spine, Inc. In February 2015, DePuy announced it would acquire Olive Medical Corporation.[20] In May 2016, DePuy Orthopaedics, Inc. acquired Biomedical Enterprises, Inc., an industry leader in small bone fixation.[21]Later in December of the same year, DePuy Synthes announced it would acquire Pulsar Vascular Inc., adding Pulsar to its Codman division.[22]
In April 2017, Irish subsidiary; DePuy Ireland Unlimited Company announced it would acquire Neuravi, a company with a portfolio of products for hemorrhagic and ischemic strokes for an undisclosed sum, with Codman Neuro being behind the deal.[23][24] In June, DePuy Synthes Products, Inc. announced it would acquire Innovative Surgical Solutions, LLC (trading as Sentio, LLC) for an undisclosed sum, bolstering the company's technology for innovative nerve localisation in spinal surgery. [25]
1999: Janssen Biotech, Inc.[edit]
Janssen Biotech, Inc., formerly known as Centocor Biotech, Inc., is a biotechnology company that was founded in Philadelphia in 1979. In 1982, Centocor transitioned into a publicly traded company. In 1999, Centocor became a wholly owned subsidiary of Johnson & Johnson. Since the acquisition, Janssen Biotech increased its annual sales from $500 million to more than $2 billion. During the same period, research and development investment increased from $75 million to more than $300 million. In 2008, Centocor, Inc. and Ortho Biotech Inc. merged to form Centocor Ortho Biotech Inc. In June 2010, Centocor Ortho Biotech acquired RespiVert, a privately held drug discovery company focused on developing small-molecule, inhaled therapies for the treatment of pulmonary diseases.[26] In June 2011, Centocor Ortho Biotech changed its name to Janssen Biotech, Inc. as part of a global effort to unite the Janssen Pharmaceutical Companies around the world under a common identity. In December 2014, the company announced it would co-develop MacroGenics cancer drug candidate (MGD011) which targets both CD19 and CD3 proteins in treating B-cell malignant tumours. This could net MacroGenics up to $700 million.[27] In January 2015, the company announced it will utilise Isis Pharmaceuticals' RNA-targeting technology to discover and develop antisense drugs targeting autoimmune disorders of the gastrointestinal tract, with the partnership potentially generating up to $835 million for Isis.[28]
Ethicon, Inc[edit]
In 1915, George F. Merson opened a facility in Edinburgh for the manufacturing, packaging and sterilizing of catgut, silk and nylon sutures. Johnson & Johnson acquired Mr. Merson’s company in 1947, and this was renamed Ethicon Suture Laboratories.[29] In 1953 this became Ethicon Inc.[30] In 1992, Ethicon was restructured, and Ethicon Endo-Surgery, Inc. became a separate corporation. During the 1990s, Ethicon diversified into new and advanced products and technologies and formed four different companies under the Ethicon umbrella, each of which specialize in different products. In 2008 J&J announced it would acquire Mentor Corporation for $1 billion and merge its operations into Ethicon.[31] In March 2016, J&Js Ethicon business unit announced it would acquire NeuWave Medical, Inc.[32] In January 2017, J&J subsidiary Ethicon announced it would acquire Megadyne Medical Products, Inc., a medical device company that develops, manufactures and markets electrosurgical tools.[33] In February 2017, Ethicon acquired medical device manufacturer, Torax Medical for an undisclosed sum.[34]
Ethicon Endo-Surgery, Inc.[edit]
Ethicon Endo-Surgery was part of Ethicon Inc. until 1992, when it became a separate corporate entity under the J&J umbrella.
Actelion[edit]
In January 2017, J&J fought off competition from Sanofi to acquire Swiss drugmaker Actelion. Later in the month J&J announced a $30 billion deal to purchase the Swiss company Actelion and to spin off its research and development unit, into a separate legal entity.[35][36] In March, the company declared its tender offer for Swiss biotechnology company Actelion successful on Friday, reporting that Janssen Holding GmbH controlled 77.2 percent of the voting rights after the main offer period,[37] equating to 83,195,346 Actelion shares. In keeping with earlier agreements, the company annoucned its intention to delist Actelion, whilst spinning out its drug discovery operations and early-stage clinical development assets into a newly created Swiss-based biopharmaceutical company, Idorsia Ltd.[38] J&J will control 16% of Idorsia, with the ability to raise their stake to 32% through convertible notes.[39]
Johnson & Johnson Vision Care, Inc[edit]
In July 2016, J&J announced its intention to acquire the privately held company, Vogue International LLC, boosting Johnson & Johnson Consumer Inc.[40] In September of the same year, J&J announced it would acquire Abbott Medical Optics from Abbott Laboratories for $4.325 billion, adding the new division into Johnson & Johnson Vision Care, Inc.[41]
In July 2017, Johnson & Johnson Vision Care, Inc announced that its Abbott Medical Optics subsidiary would acquire TearScience, who recently received FDA approval for an office-based approach to imaging meibomian glands and treating meibomian gland dysfunction.[42] In September, the company acquired subscription-based contact lens startup Sightbox.[43]
2010 onwards[edit]
In October 2010, J&J acquired Crucell for $2.4 billion.[44]
In November 2015, Biosense Webster, Inc. acquired Coherex Medical, Inc. expanding the companies range of treatment options for patients with atrial fibrillation.[45]

J&J headquarters in Madrid, Spain.
Johnson & Johnson office in Ontario
Structure[edit]
The following is an illustration of the company's structure, maintained though a number of mergers & acquisitions (this is not a comprehensive list):
Johnson & Johnson
Johnson & Johnson Consumer Inc.
Consumer Healthcare Division

Baby Care

Skin & Hair Care

Wound Care and Topicals

Oral Health Care

Women’s Health

Over-The-Counter Medicines

Nutritionals

Vogue International LLC

Medical Devices Division

Advanced Sterilization Products

Animas Corporation

Biosense Webster

Coherex Medical, Inc.

DePuy Synthes
Codman & Shurteff, Inc.

Pulsar Vascular Inc.

Neuravi

DePuy Mitek, Inc.

DePuy Orthopaedics, Inc.

Biomedical Enterprises, Inc.

DePuy Spine, Inc

DePuy Synthes Products, Inc

Sentio, LLC

Olive Medical Corporation

Ethicon, Inc.

Mentor

Acclarent

NeuWave Medical, Inc

Megadyne Medical Products, Inc.

Torax Medical

Janssen Diagnostics BVBA

Johnson & Johnson Vision Care, Inc.

Vistakon

Abbott Medical Optics

TearScience

Sightbox

LifeScan, Inc.

Ethicon Endo-Surgery

Pharmaceuticals Division
Janssen Pharmaceutica
Cilag

Covagen

Janssen-Cilag

Aragon Pharmaceuticals, Inc.

Alios BioPharma, Inc.

Novira Therapeutics, Inc.

Actelion

Janssen R&D LLC

Janssen Healthcare Innovation

Janssen Biotech, Inc.

Ortho Biotech Inc.

RespiVert

Janssen Therapeutics

Janssen Diagnostics

Janssen Scientific Affairs

Crucell

Janssen-Ortho

McNeil Nutritional LLC

Mead Johnson
(Sold to Reckitt Benckiser)

Corporate governance[edit]
Current members of the board of directors of Johnson & Johnson are: Mary Sue Coleman, James G. Cullen, Dominic Caruso, Michael M.E. Johns, Ann Dibble Jordan, Arnold G. Langbo, Susan L. Lindquist, Leo F. Mullin, William Perez, Steven S. Reinemund, David Satcher, and William C. Weldon.[46]
Sandi Peterson has served as Group Worldwide Chairman since 2012.[47]
On top of Alex Gorsky and Sandi Peterson, current members of Executive Committees of Johnson & Johnson are: Dominic Caruso, Peter Fasolo, Paul Stoffels, and Michael Sneed.[48]
JNJ Headquarters and the New Brunswick gentrification[edit]
The company has historically been located on the Delaware and Raritan Canal in New Brunswick. The company considered moving its headquarters out of New Brunswick in the 1960s, but decided to stay in the town after city officials promised to gentrify downtown New Brunswick by demolishing old buildings and constructing new ones.
While New Brunswick lost at least one historic edifice (the inn where Rutgers University began) to the redevelopment, the gentrification did attract people back to New Brunswick. Johnson & Johnson hired Henry N. Cobb from Pei Cobb Freed & Partners to design an addition to its headquarters. The white tower in a park across the railroad tracks from the older portion of the headquarters in one of tallest buildings in New Brunswick.
The stretch of Delaware and Raritan canal by the company's headquarters was replaced by a stretch of Route 18 in the late 1970s,[49] after a lengthy dispute.[50] In 2002, the company released its plan of setting up Asia-Pacific information technology headquarters in New South Wales within five years.[51]
Chairmen[edit]
Robert Wood Johnson I (1887–1910)
James Wood Johnson (1910–1932)
Robert Wood Johnson II (1932–1963)
Philip B. Hofmann (1963–1973)
Richard B. Sellars (1973–1976)
James E. Burke (1976–1989)
Ralph S. Larsen (1989–2002)
William C. Weldon (2002–2012)
Alex Gorsky (2012–present)
Products[edit]
The company's business is divided into three major segments, Pharmaceuticals, Medical Devices, and Consumer Products. In 2015, these segments contributed 44.9%, 35.9%, and 19.3%, respectively, of the company's total revenues.[52]
Pharmaceuticals[edit]
The company's major franchises in the Pharmaceutical segment include Immunology, Neuroscience, Infectious Disease, and Oncology.
Immunology products include the anti-tumor necrosis factor antibodies Remicade (infliximab), and Simponi (golimumab) used for the treatment[53] of autoimmune diseases, including rheumatoid arthritis, Crohn's disease (Remicade only), ulcerative colitis, ankylosing spondylitis, and other disorders. In 2013, these two products accounted for 29% of Johnson and Johnson's pharmaceutical revenues, and 11.3% of the company's total revenues. A third immunology product, Stelara (ustekinumab), targets interleukin-12 and interleukin-23 and is used for the treatment of psoriasis.[54]
Key infectious diseases products include Incivio (telaprevir), a hepatitis C protease inhibitor; Intelence (Etravirine), a non-nucleoside HIV polymerase inhibitor; and Prezista (darunavir), an HIV protease inhibitor. Telaprevir sales are expected to decline due to the recent approval of treatment regimens that are more efficacious and much better tolerated. Etravirine and darunavir are notable for their high barriers to resistance development.[55][56] Darunavir in combination with HIV polymerase inhibitors is recommended as a first line treatment option for treatment naive persons with HIV infection[57] but etravirine is approved only for use in treatment-experienced patients, owing in part to its requirement for twice-daily dosing.
The company's CNS products include the ADHD drug Concerta (methylphenidate extended release), and the long-acting injectable antipsychotics Invega Sustenna (paliperidone palmitate) and Risperdal Consta (risperidone). Invega Sustenna and Risperdal Consta were the first widely utilized long-acting depot injections for the treatment of schizophrenia. Designed to address the issue of poor patient compliance with oral therapy, they are administered by intramuscular injection at intervals of 2 weeks and one month, respectively. Only minimal improvements in outcomes relative to the oral versions of these drugs were observed in the clinical trial setting, but some evidence suggests that the advantages of long-acting injections in clinical practice may be greater than is readily demonstrated in the environment of a clinical trial.[58][59][60]
Oncology products include Velcade (bortezomib), for the treatment of multiple myeloma and mantle cell lymphoma[61] and Zytiga (abiraterone), an androgen antagonist for the treatment of prostate cancer. In clinical trials, abiraterone treatment was associated with a 4.6 to 5.2 survival advantage when used either before or after chemotherapy with platinum based drugs.[62] On December 31, 2012, the Food and Drug Administration approved Sirturo (bedaquiline), a Johnson & Johnson tuberculosis drug that is the first new medicine to fight the infection in more than forty years.[63]
Medical devices[edit]
Sectors in which the company is active[64] include:
Aesthetics (Ethicon, Mentor)
Arrhythmias (Biosense Webster)
Bariatric Surgery for Obesity (Ethicon)
Cardiovascular Disease (Biosense Webster, Inc.)
Diabetes Care (LifeScan, Animas Corporation)
Ear, Nose, and Throat Conditions (Acclarent)
General Surgery (Ethicon, Codman Neuro)
Hernia Surgery (Ethicon)
Insulin Delivery Devices (Animas)
Neurovascular Disease (Codman Neuro, DePuy Synthes)
Orthopaedics (DePuy Synthes): Joint Reconstruction, Trauma, Spine, Sports Medicine and Power Tools
Self-Measured Blood Glucose Monitors (LifeScan)
Surgical Instruments and Infection Prevention(Advanced Sterilization Products)
Urologic Surgery (Ethicon)
Vision Care (VISTAKON®)
Consumer health[edit]
Sectors in which the company is active[65] include:
Baby Care
Nutritionals
Oral Health Care
Over-the-Counter Medicines
Skin & Hair Care
Vision Care
Wound Care & Topicals
Environmental record[edit]
Johnson & Johnson has set several positive goals to keep the company environmentally friendly and was ranked third among the United States's largest companies in Newsweek's "Green Rankings".[66] Some examples are the reduction in water use, waste, and energy use and an increased level of transparency.[67] Johnson & Johnson agreed to change its packaging of plastic bottles used in the manufacturing process, switching their packaging of liquids to non-polycarbonate containers.[68] The corporation is working with the Climate Northwest Initiative and the EPA National Environmental Performance Track program.[69] As a member of the national Green Power Partnership, Johnson & Johnson operates the largest solar power generator in Pennsylvania at its site in Spring House, PA.[70]
Recalls and litigation[edit]
1982 Chicago Tylenol murders[edit]
Main article: Chicago Tylenol murders
On September 29, 1982, a "Tylenol scare" began when the first of seven individuals died in Chicago metropolitan area, after ingesting Extra Strength Tylenol that had been deliberately laced with cyanide.[71] Within a week, the company pulled 31 million bottles of capsules back from retailers, making it one of the first major recalls in American history.[71] The incident led to reforms in the packaging of over-the-counter substances and to federal anti-tampering laws. The case remains unsolved and no suspects have been charged. Johnson & Johnson's quick response, including a nationwide recall, was widely praised by public relations experts and the media and was the gold standard for corporate crisis management.[72][73][74]
2010 children's product recall[edit]
Main article: 2010 Johnson & Johnson children's product recall
On April 30, 2010, McNeil Consumer Healthcare, a subsidiary of Johnson and Johnson, voluntarily recalled 43 over-the-counter children's medicines, including Tylenol, Tylenol Plus, Motrin, Zyrtec and Benadryl. The recall was conducted after a routine inspection at a manufacturing facility in Fort Washington, Pennsylvania, United States revealed that some "products may not fully meet the required manufacturing specifications".[75][76] Affected products may contain a "higher concentration of active ingredients" or exhibit other manufacturing defects.[76] Products shipped to Canada, Dominican Republic, Guam, Guatemala, Jamaica, Puerto Rico, Panama, Trinidad and Tobago, the United Arab Emirates, Kuwait and Fiji were included in the recall.[75] In a statement, Johnson & Johnson said "a comprehensive quality assessment across its manufacturing operations" was underway.[75][76] A dedicated website was established by the company listing affected products and other consumer information.[76]
2010 hip-replacement recall[edit]
Main article: 2010 DePuy Hip Recall
On August 2009, 2010, DePuy, a subsidiary of American giant Johnson & Johnson, recalled its ASR (articular surface replacement) hip prostheses from the market. DePuy said the recall was due to unpublished National Joint Registry data showing a 12% revision rate for resurfacing at five years and an ASR XL revision rate of 13%. All hip prostheses fail in some patients, but it is expected that the rate will be about 1% a year.[77] Pathologically, the failing prosthesis had several effects. Metal debris from wear of the implant led to a reaction that destroyed the soft tissues surrounding the joint, leaving some patients with long term disability. Ions of cobalt and chromium—the metals from which the implant was made—were also released into the blood and cerebral spinal fluid in some patients.[78]
In March 2013, a jury in Los Angeles ordered Johnson & Johnson to pay more than $8.3 million in damages to a Montana man in the first of more than 10,000 lawsuits pending against the company in connection with the now-recalled DePuy hip.[79]
Some lawyers and industry analysts have estimated that the suits ultimately will cost Johnson & Johnson billions of dollars to resolve.[79]
2010 Tylenol recall[edit]
In 2010 and 2011, Johnson & Johnson voluntarily recalled some over-the-counter products including Tylenol due to an odor caused by tribromoanisole.[80][81] In this case, 2,4,6-tribromophenol was used to treat wooden pallets on which product packaging materials were transported and stored.[80]
Shareholders lawsuit[edit]
In 2010 a group of shareholders sued the board for allegedly failing to take action to prevent serious failings and illegalities since the 1990s, including manufacturing problems, bribing officials, covering up adverse effects and misleading marketing for unapproved uses. The judge initially dismissed the case in September 2011, but allowed the plaintiffs opportunity to refile at a later time.[82] In 2012 Johnson and Johnson proposed a settlement with the shareholders, whereby the company would institute new oversight, quality and compliance procedures binding for five years.[83]
Illegal marketing of Risperdal[edit]
Juries in several US states have found J&J guilty of concealing the adverse effects of Janssen Pharmaceuticals' antipsychotic medication Risperdal, produced by its unit, in order to promote it to doctors and patients as better than cheaper generics, and of falsely marketing it for treating patients with dementia.[84] States that have awarded damages include Texas ($158 million), South Carolina ($327 million), Louisiana ($258 million), and most notably Arkansas ($1.2 billion).[85]
In 2010, the United States Department of Justice joined a whistleblowers suit accusing the company of illegally marketing Risperdal through Omnicare, the largest company supplying pharmaceuticals to nursing homes.[86][87] The allegations include that J&J were warned by the U.S. Food and Drug Administration (FDA) not to promote Risperdal as effective and safe for elderly patients, but they did so, and that they paid Omnicare to promote the drug to care home physicians.[88] The settlement was finalized on November 4, 2013, with J&J agreeing to pay a penalty of around $2.2 billion, "including criminal fines and forfeiture totaling $485 million and civil settlements with the federal government and states totaling $1.72 billion."[89]
Johnson & Johnson has also been subject to congressional investigations related to payments given to psychiatrists to promote its products and ghost write articles, notably Joseph Biederman and his pediatric bipolar disorder research unit.[90]
Foreign bribery[edit]
In 2011, J&J settled litigation brought by the US Securities and Exchange Commission under the Foreign Corrupt Practices Act and paid around $70M in disgorgement and fines.[91] J&J's employees had given kickbacks and bribes to doctors in Greece, Poland, and Romania to obtain business selling drugs and medical devices and had bribed officials in Iraq to win contracts under the Oil for Food program.[92] J&J fully cooperated with the investigation once the problems came to light.[93]
Consumer Fraud Settlements[edit]
In May 2017, J&J reached an agreement to pay $33 million to several states to settle consumer fraud allegations in some of the company’s over-the-counter drugs.[94][95][96]
Use of the Red Cross symbol[edit]
Flag of the Red Cross
Further information: Emblems of the International Red Cross and Red Crescent Movement § Use of the emblems
Johnson & Johnson registered the Red Cross as a U.S. trademark for "medicinal and surgical plasters" in 1905 and has used the design since 1887.[97] The Geneva Conventions, which reserved the Red Cross emblem for specific uses, were first approved in 1864 and ratified by the United States in 1882. However, the emblem was not protected by U.S. law for the use of the American Red Cross and the U.S. military until after Johnson & Johnson had obtained its trademark. A clause in this law (now 18 U.S.C. 706) permits this pre-existing uses of the Red Cross to continue.
A declaration made by the U.S. upon its ratification of the 1949 Geneva Conventions includes a reservation that pre-1905 U.S. domestic uses of the Red Cross, such as Johnson & Johnson's, would remain lawful as long as the cross is not used on "aircraft, vessels, vehicles, buildings or other structures, or upon the ground," i.e., uses which could be confused with its military uses.[98] This means that the U.S. did not agree to any interpretation of the 1949 Geneva Conventions that would overrule Johnson & Johnson's trademark. The American Red Cross continues to recognize the validity of Johnson & Johnson's trademark.[99]
In August 2007, Johnson & Johnson filed a lawsuit against the American Red Cross (ARC), demanding that the charity halt the use of the red cross symbol on products it sells to the public, though the company takes no issue with the charity's use of the mark for non-profit purposes.[100] In May 2008, the judge in the case dismissed most of Johnson & Johnson's claims, and a month later the two organizations announced a settlement had been reached in which both parties would continue to use the symbol.[101]
Boston Scientific lawsuits[edit]
Since 2003, Johnson & Johnson and Boston Scientific have both claimed that the other had infringed on their patents covering heart stent medical devices. The litigation was settled when Boston Scientific agreed to pay $716 million to Johnson & Johnson in September 2009 and an additional $1.73 billion in February 2010.[102] Their dispute was renewed in 2014, now on the grounds of a contract dispute.[103]
Patent-infringement case against Abbott[edit]
In 2007, Johnson & Johnson sued Abbott Laboratories over the development and sale of the arthritis drug Humira. Johnson & Johnson claimed that Abbott used technology patented by New York University and licensed exclusively to Johnson & Johnson's Centocor division to develop Humira. Johnson & Johnson won the court case, and in 2009 Abbott was ordered to pay Johnson & Johnson $1.17 billion in lost revenues and $504 million in royalties.[104] The judge also added $175.6 million in interest to bring the total to $1.84 billion.[105] This was the largest patent-infringement award in U.S. history[104] until the 2013 decision against Teva in favor of Takeda and Pfizer for over 2.1 billion dollars.[106] Abbott has since successfully reversed the verdict at appeal.[107]
Vaginal mesh implants[edit]
Tens of thousands of women worldwide have taken legal action against Johnson & Johnson after suffering serious complications following a vaginal mesh implant procedure.[108] In 2016 the U.S. states of California and Washington filed a lawsuit against the company, accusing it of deception.[109] More than 700 women began a class action against the company in the Federal Court of Australia in 2017, telling the court they "suffered irreparable, debilitating pain after the devices began to erode into surrounding tissue and organs, causing infections and complications." The class action alleged that Johnson & Johnson, which "aggressively marketed" the implants "failed to properly warn patients and surgeons of the risk, or test the devices adequately."[110]
Baby powder[edit]
In February 2016, J&J was ordered to pay $72 million in damages to the family of Jacqueline Fox, a 62-year-old woman who died of ovarian cancer in 2015.[111] She had been sprinkling Johnson's Baby Powder on her underwear nearly every day since she was a teenager. J&J claimed that the safety of cosmetic talc is supported by decades of scientific evidence and it plans to appeal the verdict. The British charity, Ovacome was quoted as saying that while there were 16 studies which showed that using talc increased the risk of ovarian cancer by around a third and that a 2013 review of US studies came up with similar results for genital, but not general talcum powder use, J&J were not convinced that the results were reliable. Furthermore, Ovacome said, "Ovarian cancer is a rare disease, and increasing a small risk by a third still [still] gives a small risk."[111]
By March 2017, over 1,000 U.S. women had sued J&J for covering up the possible cancer risk from its Baby Powder product; the company says that 70 percent of its Baby Powder is used by adults.[112]
On August 21, 2017, a California jury ordered Johnson & Johnson to pay $417 million to a woman who claimed she developed ovarian cancer after using the company's talc-based products like Johnson's Baby Powder for feminine hygiene. The verdict included $70 million in compensatory damages and $347 million in punitive damages. J&J says they will appeal the verdict, believing that science supports the safety of their baby powder. [113]
On October 18, 2017, the Missouri Eastern District appeals court on Tuesday threw out a $ 72 million jury verdict. The appeals court ruled 3-0 that Jacqueline Fox's lawsuit lacked jurisdiction in Missouri because of a U.S Supreme Court decision that imposed limits on where injury lawsuit can be filed which lawsuit's jurisdiction requires a stronger connection between the forum state and a plaintiff's claims. Fox, 62, of Birmingham, Ala., died in 2015, about four months before her trial was held in St. Louis Circuit Court. She was among 65 plaintiffs; of whom only two were from Missouri. Subsequently it also would kill three other recent St. Louis jury verdicts of more than $ 200 million combined. [114]
See also[edit]
New Jersey portal
Companies portal
Medicine portal
Frederick Barnett Kilmer – Director of Scientific Laboratories from 1889 to 1934.
Zodiac – Historic schooner built for the Johnson family heirs.
References[edit]
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